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Xandra O. Breakefield
Xandra O. Breakefield
Harvard Medical School; Massachusetts General Hospital
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Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …
C Théry, KW Witwer, E Aikawa, MJ Alcaraz, JD Anderson, ...
Journal of extracellular vesicles 7 (1), 1535750, 2018
80992018
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
J Skog, T Würdinger, S Van Rijn, DH Meijer, L Gainche, WT Curry Jr, ...
Nature cell biology 10 (12), 1470-1476, 2008
54932008
Extracellular vesicles: biology and emerging therapeutic opportunities
S El Andaloussi, I Mäger, XO Breakefield, MJA Wood
Nature reviews Drug discovery 12 (5), 347-357, 2013
29922013
Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A
HG Brunner, M Nelen, XO Breakefield, HH Ropers, BA Van Oost
Science 262 (5133), 578-580, 1993
21751993
Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas
KS Aboody, A Brown, NG Rainov, KA Bower, S Liu, W Yang, JE Small, ...
Proceedings of the National Academy of Sciences 97 (23), 12846-12851, 2000
16742000
Introduction to extracellular vesicles: biogenesis, RNA cargo selection, content, release, and uptake
ER Abels, XO Breakefield
Cellular and molecular neurobiology 36, 301-312, 2016
14942016
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
H Kalra, RJ Simpson, H Ji, E Aikawa, P Altevogt, P Askenase, VC Bond, ...
PLoS biology 10 (12), e1001450, 2012
13242012
Extracellular vesicles: unique intercellular delivery vehicles
SLN Maas, XO Breakefield, AM Weaver
Trends in cell biology 27 (3), 172-188, 2017
12802017
Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences
L Balaj, R Lessard, L Dai, YJ Cho, SL Pomeroy, XO Breakefield, J Skog
Nature communications 2 (1), 180, 2011
12782011
New technologies for analysis of extracellular vesicles
H Shao, H Im, CM Castro, X Breakefield, R Weissleder, H Lee
Chemical reviews 118 (4), 1917-1950, 2018
12282018
The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein
LJ Ozelius, JW Hewett, CE Page, SB Bressman, PL Kramer, C Shalish, ...
Nature genetics 17 (1), 40-48, 1997
12111997
RNA delivery by extracellular vesicles in mammalian cells and its applications
K O’Brien, K Breyne, S Ughetto, LC Laurent, XO Breakefield
Nature reviews Molecular cell biology 21 (10), 585-606, 2020
11432020
Extracellular vesicles: composition, biological relevance, and methods of study
MŁP Zaborowski, L Balaj, XO Breakefield, CP Lai
Bioscience 65 (8), 783-797, 2015
10572015
Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer
J Nilsson, J Skog, A Nordstrand, V Baranov, L Mincheva-Nilsson, ...
British journal of cancer 100 (10), 1603-1607, 2009
9202009
Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo
BA Tannous, DE Kim, JL Fernandez, R Weissleder, XO Breakefield
Molecular Therapy 11 (3), 435-443, 2005
8142005
Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy
H Shao, J Chung, L Balaj, A Charest, DD Bigner, BS Carter, FH Hochberg, ...
Nature medicine 18 (12), 1835-1840, 2012
7972012
Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter
CP Lai, O Mardini, M Ericsson, S Prabhakar, CA Maguire, JW Chen, ...
ACS nano 8 (1), 483-494, 2014
7752014
Advances in therapeutic applications of extracellular vesicles
OPB Wiklander, MÁ Brennan, J Lötvall, XO Breakefield, S El Andaloussi
Science translational medicine 11 (492), eaav8521, 2019
7292019
Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons.
P Levitt, JE Pintar, XO Breakefield
Proceedings of the National Academy of Sciences 79 (20), 6385-6389, 1982
6801982
Microfluidic isolation and transcriptome analysis of serum microvesicles
C Chen, J Skog, CH Hsu, RT Lessard, L Balaj, T Wurdinger, BS Carter, ...
Lab on a Chip 10 (4), 505-511, 2010
6332010
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