| Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts X Zhang, P Yue, BDG Page, T Li, W Zhao, AT Namanja, D Paladino, ... Proceedings of the National Academy of Sciences 109 (24), 9623-9628, 2012 | 367 | 2012 |
| Substrate recognition reduces side-chain flexibility for conserved hydrophobic residues in human Pin1 AT Namanja, T Peng, JS Zintsmaster, AC Elson, MG Shakour, JW Peng Structure 15 (3), 313-327, 2007 | 100 | 2007 |
| Stereospecific gating of functional motions in Pin1 AT Namanja, XJ Wang, B Xu, AY Mercedes-Camacho, KA Wilson, ... Proceedings of the National Academy of Sciences 108 (30), 12289-12294, 2011 | 89 | 2011 |
| Insights into high affinity small ubiquitin-like modifier (SUMO) recognition by SUMO-interacting motifs (SIMs) revealed by a combination of NMR and peptide array analysis AT Namanja, YJ Li, Y Su, S Wong, J Lu, LT Colson, C Wu, SSC Li, Y Chen Journal of Biological Chemistry 287 (5), 3231-3240, 2012 | 87 | 2012 |
| Hydroxamic Acid and Benzoic Acid–Based STAT3 Inhibitors Suppress Human Glioma and Breast Cancer Phenotypes In Vitro and In Vivo P Yue, F Lopez-Tapia, D Paladino, Y Li, CH Chen, AT Namanja, T Hilliard, ... Cancer research 76 (3), 652-663, 2016 | 75 | 2016 |
| Sequence-specific dynamics modulate recognition specificity in WW domains T Peng, JS Zintsmaster, AT Namanja, JW Peng Nature structural & molecular biology 14 (4), 325-331, 2007 | 75 | 2007 |
| Toward flexibility− activity relationships by NMR spectroscopy: dynamics of Pin1 ligands AT Namanja, XJ Wang, B Xu, AY Mercedes-Camacho, BD Wilson, ... Journal of the American Chemical Society 132 (16), 5607-5609, 2010 | 62 | 2010 |
| Identification and characterization of a new chemotype of noncovalent SENP inhibitors IG Madu, AT Namanja, Y Su, S Wong, YJ Li, Y Chen ACS chemical biology 8 (7), 1435-1441, 2013 | 43 | 2013 |
| Mapping the dynamics of ligand reorganization via 13CH3 and 13CH2 relaxation dispersion at natural abundance JW Peng, BD Wilson, AT Namanja Journal of biomolecular NMR 45, 171-183, 2009 | 34 | 2009 |
| Allosteric communication across STAT3 domains associated with STAT3 function and disease-causing mutation AT Namanja, J Wang, R Buettner, L Colson, Y Chen Journal of molecular biology 428 (3), 579-589, 2016 | 26 | 2016 |
| Selective editing of Val and Leu methyl groups in high molecular weight protein NMR W Hu, AT Namanja, S Wong, Y Chen Journal of biomolecular NMR 53, 113-124, 2012 | 19 | 2012 |
| NMR-based fragment screening and lead discovery accelerated by principal component analysis AT Namanja, J Xu, H Wu, Q Sun, AK Upadhyay, C Sun, SR Van Doren, ... Journal of Biomolecular NMR 73, 675-685, 2019 | 18 | 2019 |
| Conformational flexibility and changes underlying activation of the SUMO-specific protease SENP1 by remote substrate binding CH Chen, AT Namanja, Y Chen Nature communications 5 (1), 4968, 2014 | 14 | 2014 |
| Molecular basis for signal transduction in the bimodular cell-cycle enzyme Pin1 AT Namanja University of Notre Dame, 2009 | 3 | 2009 |
| Efficiently driving protein-based fragment screening and lead discovery using two-dimensional NMR C Peng, AT Namanja, E Munoz, H Wu, TE Frederick, M Maestre-Martinez, ... Journal of Biomolecular NMR 77 (1), 39-53, 2023 | 1 | 2023 |
| Insights into the conformation and self-association of a concentrated monoclonal antibody using isothermal chemical denaturation and nuclear magnetic resonance J Xu, A Namanja, SL Chan, C Son, AM Petros, C Sun, C Radziejewski, ... Journal of Pharmaceutical Sciences 110 (12), 3819-3828, 2021 | 1 | 2021 |
| Methods of identifying SENP1 inhibitors Y Chen, CH Chen, A Namanja US Patent 11,041,859, 2021 | | 2021 |
| NMR based fragment screening and lead discovery accelerated by principal component analysis J Xu, A Petros, C Sun, S Van Doren, Q Sun, H Wu, A Upadhyay, ... American Chemical Society SciMeetings 1 (2), 2020 | | 2020 |
| NMR discovery and molecular-basis of small molecule inhibitors of STAT3 AT Namanja, R Buettner, R Jove, Y Chen Cancer Research 74 (19_Supplement), 1636-1636, 2014 | | 2014 |
| Toward Flexibility− Activity AT Namanja Journal of the American, 2010 | | 2010 |
