| Fold change of nuclear NF-κB determines TNF-induced transcription in single cells REC Lee, SR Walker, K Savery, DA Frank, S Gaudet Molecular cell 53 (6), 867-879, 2014 | 257 | 2014 |
| Metacaspase Yca1 is required for clearance of insoluble protein aggregates REC Lee, S Brunette, LG Puente, LA Megeney Proceedings of the National Academy of Sciences 107 (30), 13348-13353, 2010 | 182 | 2010 |
| A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics REC Lee, LG Puente, M Kærn, LA Megeney PloS one 3 (8), e2956, 2008 | 110 | 2008 |
| NF-κB dynamics discriminate between TNF doses in single cells Q Zhang, S Gupta, DL Schipper, GJ Kowalczyk, AE Mancini, JR Faeder, ... Cell systems 5 (6), 638-645. e5, 2017 | 73 | 2017 |
| NF-κB signalling and cell fate decisions in response to a short pulse of tumour necrosis factor REC Lee, MA Qasaimeh, X Xia, D Juncker, S Gaudet Scientific Reports 6 (1), 39519, 2016 | 56 | 2016 |
| A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts JDR Knight, R Tian, REC Lee, F Wang, A Beauvais, H Zou, LA Megeney, ... Skeletal muscle 2, 1-12, 2012 | 56 | 2012 |
| NF-κB-chromatin interactions drive diverse phenotypes by modulating transcriptional noise VC Wong, VL Bass, ME Bullock, AK Chavali, REC Lee, W Mothes, ... Cell reports 22 (3), 585-599, 2018 | 49 | 2018 |
| Cell-to-cell variability in cell death: can systems biology help us make sense of it all? X Xia, MS Owen, RE Lee, S Gaudet Cell death & disease 5, e1261, 2014 | 44 | 2014 |
| Demystifying the cytokine network: Mathematical models point the way PA Morel, REC Lee, JR Faeder Cytokine 98, 115-123, 2017 | 35 | 2017 |
| Reconstructing the Regulatory Kinase Pathways of Myogenesis from Phosphopeptide Data* S LG Puente, S Voisin, REC Lee, LA Megeney Molecular & Cellular Proteomics 5 (12), 2244-2251, 2006 | 34 | 2006 |
| A network-centric approach to drugging TNF-induced NF-κB signaling NA Pabon, Q Zhang, JA Cruz, DL Schipper, CJ Camacho, REC Lee Nature communications 10 (1), 860, 2019 | 28 | 2019 |
| Evaluation of parallel tempering to accelerate Bayesian parameter estimation in systems biology S Gupta, L Hainsworth, J Hogg, R Lee, J Faeder 2018 26th Euromicro International Conference on Parallel, Distributed and …, 2018 | 27 | 2018 |
| Parallel Tempering with Lasso for model reduction in systems biology S Gupta, REC Lee, JR Faeder PLoS computational biology 16 (3), e1007669, 2020 | 22 | 2020 |
| Dopamine D2 receptor modulates Wnt expression and control of cell proliferation F Han, P Konkalmatt, C Mokashi, M Kumar, Y Zhang, A Ko, ZJ Farino, ... Scientific reports 9 (1), 16861, 2019 | 22 | 2019 |
| A system for analog control of cell culture dynamics to reveal capabilities of signaling networks CS Mokashi, DL Schipper, MA Qasaimeh, REC Lee Iscience 19, 586-596, 2019 | 16 | 2019 |
| The yeast kinome displays scale free topology with functional hub clusters REC Lee, LA Megeney BMC bioinformatics 6, 1-9, 2005 | 15 | 2005 |
| A variable-gain stochastic pooling motif mediates information transfer from receptor assemblies into NF-κB JA Cruz, CS Mokashi, GJ Kowalczyk, Y Guo, Q Zhang, S Gupta, ... Science Advances 7 (30), eabi9410, 2021 | 13 | 2021 |
| Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors M Singh, K Warita, T Warita, JR Faeder, REC Lee, S Sant, ZN Oltvai Scientific reports 8 (1), 9388, 2018 | 13 | 2018 |
| Spatial Stochastic Modeling with MCell and CellBlender S Gupta, J Czech, R Kuczewski, TM Bartol, TJ Sejnowski, REC Lee, ... Quantitative Biology: Theory, Computational Methods, and Models, 485-511, 2018 | 9 | 2018 |
| dNEMO: a tool for quantification of mRNA and punctate structures in time-lapse images of single cells GJ Kowalczyk, JA Cruz, Y Guo, Q Zhang, N Sauerwald, REC Lee Bioinformatics 37 (5), 677-683, 2021 | 6 | 2021 |
Suzanne GaudetAssociate Director, Novartis Institutes for Biomedical ResearchVerified email at novartis.com
