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Natura Myeku
Natura Myeku
Associate Professor, Columbia University Medical Center
Verified email at cumc.columbia.edu
Title
Cited by
Cited by
Year
Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling
N Myeku, CL Clelland, S Emrani, NV Kukushkin, WH Yu, AL Goldberg, ...
Nature medicine 22 (1), 46-53, 2016
4072016
Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo
EE Congdon, JW Wu, N Myeku, YH Figueroa, M Herman, PS Marinec, ...
Autophagy 8 (4), 609-622, 2012
3202012
Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62
N Myeku, ME Figueiredo-Pereira
Journal of Biological Chemistry 286 (25), 22426-22440, 2011
2512011
Proteasome–caspase–cathepsin sequence leading to tau pathology induced by prostaglandin J2 in neuronal cells
LT Arnaud, N Myeku, ME Figueiredo‐Pereira
Journal of neurochemistry 110 (1), 328-342, 2009
722009
Targeting the 26S proteasome to protect against proteotoxic diseases
N Myeku, KE Duff
Trends in molecular medicine 24 (1), 18-29, 2018
502018
Assessment of proteasome impairment and accumulation/aggregation of ubiquitinated proteins in neuronal cultures
N Myeku, MJ Metcalfe, Q Huang, M Figueiredo-Pereira
Neurodegeneration: Methods and Protocols, 273-296, 2011
402011
cAMP stimulates the ubiquitin/proteasome pathway in rat spinal cord neurons
N Myeku, H Wang, ME Figueiredo-Pereira
Neuroscience letters 527 (2), 126-131, 2012
392012
Cilostazol, a phosphodiesterase 3 inhibitor, activates proteasome-mediated proteolysis and attenuates tauopathy and cognitive decline
AW Schaler, N Myeku
Translational Research 193, 31-41, 2018
312018
DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1
EK Boamah, A Brekman, M Tomasz, N Myeku, M Figueiredo-Pereira, ...
Chemical research in toxicology 23 (7), 1151-1162, 2010
262010
Noncoding translation mitigation
JS Kesner, Z Chen, P Shi, AO Aparicio, MR Murphy, Y Guo, A Trehan, ...
Nature 617 (7960), 395-402, 2023
252023
PAC1 receptor–mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain
AW Schaler, AM Runyan, CL Clelland, EJ Sydney, SL Fowler, ...
Science translational medicine 13 (595), eaba7394, 2021
192021
21 Ubiquitin/Proteasome and Autophagy/Lysosome Pathways: Comparison and Role in Neurodegeneration
NMME Figueiredo-Pereira
Handbook of Neurochemistry and Molecular Neurobiology, 2009
62009
1′-Acetoxychavicol Acetate Increases Proteasome Activity by Activating cAMP-PKA Signaling
K Yaku, I Matsui-Yuasa, A Kojima-Yuasa
Planta Medica 84 (03), 153-159, 2018
42018
5-HT4 receptor agonists treatment reduces tau pathology and behavioral deficit in the PS19 mouse model of tauopathy
S Jiang, EJ Sydney, AM Runyan, R Serpe, M Srikanth, HY Figueroa, ...
Frontiers in Cellular Neuroscience 18, 1338502, 2024
12024
Investigating changes in the proteostasis capabilities of iPSC‐neurons during development and in FTD using iPSC‐neurons with MAPT mutations
G Lines, C Arber, E Preza, CA Leckey, N Myeku, JM Casey, M Perkinton, ...
Alzheimer's & Dementia 17, e058308, 2021
12021
GPCR-mediated clearance of tau in post-synaptic compartments attenuates tau pathology in vivo
AW Schaler, AM Runyan, SL Fowler, HY Figueroa, S Shioda, ...
bioRxiv, 2020.01. 21.914135, 2020
12020
O4‐11‐03: Interaction between the ubiquitin proteasome system, autophagy and progressive tauopathy in vivo
N Myeku, WH Yu, K Duff
Alzheimer's & Dementia 8 (4S_Part_17), P636-P637, 2012
12012
Modulation of the Immunoproteasome Affects Pathological Tau Aggregation in Alzheimer’s Disease
Z Nashman, A Runyan, E Sydney, N Myeku
Alzheimer's & Dementia 19, e071413, 2023
2023
P3‐154: STOPPING TRANS‐SYNAPTIC PROPAGATION OF TAU BY RECEPTOR‐MEDIATED CLEARANCE OF POST‐SYNAPTIC TAU
N Myeku
Alzheimer's & Dementia 14 (7S_Part_21), P1127-P1127, 2018
2018
CAMP Enhances 26S Proteasome Activity, P62/sequestosome1 Levels and Survival of Rat Spinal Cord Neuronal Cultures
N Myeku
Cornell University, 2011
2011
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