| O–H Hydrogen bonding promotes H-atom transfer from α C–H bonds for C-alkylation of alcohols JL Jeffrey, JA Terrett, DWC MacMillan Science, 2015 | 443 | 2015 |
| Intramolecular C (sp 3)–H amination JL Jeffrey, R Sarpong Chemical Science 4 (11), 4092-4106, 2013 | 326 | 2013 |
| Selective Radical–Radical Cross-Couplings: Design of a Formal β-Mannich Reaction JL Jeffrey, FR Petronijevic, DWC MacMillan Journal of the American Chemical Society 137 (26), 8404-8407, 2015 | 234 | 2015 |
| Concise synthesis of pauciflorol F using a larock annulation JL Jeffrey, R Sarpong Organic Letters 11 (23), 5450-5453, 2009 | 150 | 2009 |
| An approach to the synthesis of dimeric resveratrol natural products via a palladium-catalyzed domino reaction JL Jeffrey, R Sarpong Tetrahedron letters 50 (17), 1969-1972, 2009 | 79 | 2009 |
| Discovery of AB680: a potent and selective inhibitor of CD73 KV Lawson, J Kalisiak, EA Lindsey, ET Newcomb, MR Leleti, L Debien, ... Journal of Medicinal Chemistry 63 (20), 11448-11468, 2020 | 59 | 2020 |
| Targeting metabolism of extracellular nucleotides via inhibition of ectonucleotidases CD73 and CD39 JL Jeffrey, KV Lawson, JP Powers Journal of Medicinal Chemistry 63 (22), 13444-13465, 2020 | 58 | 2020 |
| Photoredox-catalyzed deoxyfluorination of activated alcohols with Selectfluor® M González-Esguevillas, J Miró, JL Jeffrey, DWC MacMillan Tetrahedron, 2019 | 58 | 2019 |
| Safety, tolerability, and pharmacology of AB928, a novel dual adenosine receptor antagonist, in a randomized, phase 1 study in healthy volunteers L Seitz, L Jin, M Leleti, D Ashok, J Jeffrey, A Rieger, RG Tiessen, G Arold, ... Investigational New Drugs 37 (4), 711-721, 2019 | 46 | 2019 |
| Intramolecular C(sp3)-N Coupling by Oxidation of Benzylic C,N-Dianions JL Jeffrey, ES Bartlett, R Sarpong Angewandte Chemie International Edition 52 (8), 2194-2197, 2013 | 45 | 2013 |
| Discovery of potent and selective non-nucleotide small molecule inhibitors of CD73 JW Beatty, EA Lindsey, R Thomas-Tran, L Debien, D Mandal, JL Jeffrey, ... Journal of medicinal chemistry 63 (8), 3935-3955, 2020 | 40 | 2020 |
| Discovery of potent and selective PI3Kγ inhibitors SL Drew, R Thomas-Tran, JW Beatty, J Fournier, KV Lawson, DH Miles, ... Journal of Medicinal Chemistry 63 (19), 11235-11257, 2020 | 32 | 2020 |
| Chichibabin-type direct alkylation of pyridyl alcohols with alkyl lithium reagents JL Jeffrey, R Sarpong Organic letters 14 (21), 5400-5403, 2012 | 32 | 2012 |
| Molecular iodine catalysed benzylic sp3 C–H bond amination for the synthesis of 2-arylquinazolines from 2-aminobenzaldehydes, 2-aminobenzophenones and 2-aminobenzyl alcohols DS Deshmukh, BM Bhanage Synlett 29 (07), 979-985, 2018 | 27 | 2018 |
| A bond-weakening borinate catalyst that improves the scope of the photoredox α-C–H alkylation of alcohols K Sakai, K Oisaki, M Kanai Synthesis 52 (15), 2171-2189, 2020 | 22 | 2020 |
| Electrophilic activation of amides for the preparation of polysubstituted pyrimidines T Stopka, P Adler, G Hagn, H Zhang, V Tona, N Maulide Synthesis 51 (01), 194-202, 2019 | 17 | 2019 |
| Synthesis of 1-Substituted Benzo[c]isoxazol-3(1H)-imines via Tandem Nitroso-Ene/Intramolecular Cyclizations of 2-Nitrosobenzonitrile JL Jeffrey, SP McClintock, MM Haley The Journal of Organic Chemistry 73 (8), 3288-3291, 2008 | 16 | 2008 |
| Discovery of potent and selective 7-azaindole isoindolinone-based PI3Kγ inhibitors DH Miles, X Yan, R Thomas-Tran, J Fournier, EU Sharif, SL Drew, G Mata, ... ACS Medicinal Chemistry Letters 11 (11), 2244-2252, 2020 | 15 | 2020 |
| Synthesis of Indoline-2, 3-diones by Radical Coupling of Indolin-2-ones with tert-Butyl Hydroperoxide WW Ying, WM Zhu, H Liang, WT Wei Synlett 29 (02), 215-218, 2018 | 14 | 2018 |
| Azolopyrimidine for the treatment of cancer-related disorders J Beatty, L Debien, J Jeffrey, MR Leleti, D Mandal, D Miles, J Powers, ... US Patent 10,399,962, 2019 | 10 | 2019 |
Michael M. HaleyRichard M. & Patricia H. Noyes Professor of Chemistry, University of OregonVerified email at uoregon.edu
