| MDM2 antagonists activate p53 and synergize with genotoxic drugs in B-cell chronic lymphocytic leukemia cells L Coll-Mulet, D Iglesias-Serret, AF Santidrián, AM Cosialls, M de Frias, ... Blood 107 (10), 4109-4114, 2006 | 257 | 2006 |
| Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-β–induced cell death through impairing up-regulation of the NADPH oxidase NOX4 L Caja, P Sancho, E Bertran, D Iglesias-Serret, J Gil, I Fabregat Cancer research 69 (19), 7595-7602, 2009 | 140 | 2009 |
| Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-β–induced cell death through impairing up-regulation of the NADPH oxidase NOX4 L Caja, P Sancho, E Bertran, D Iglesias-Serret, J Gil, I Fabregat Cancer research 69 (19), 7595-7602, 2009 | 140 | 2009 |
| AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells AF Santidrián, DM González-Gironès, D Iglesias-Serret, L Coll-Mulet, ... Blood, The Journal of the American Society of Hematology 116 (16), 3023-3032, 2010 | 125 | 2010 |
| Bcl-2 inhibitors induce apoptosis in chronic lymphocytic leukemia cells C Campàs, AM Cosialls, M Barragán, D Iglesias-Serret, AF Santidrián, ... Experimental hematology 34 (12), 1663-1669, 2006 | 118 | 2006 |
| Transcriptional and translational control of Mcl-1 during apoptosis D Iglesias-Serret, M Piqué, J Gil, G Pons, JM López Archives of biochemistry and biophysics 417 (2), 141-152, 2003 | 100 | 2003 |
| Regulation of Akt/PKB by phosphatidylinositol 3-kinase-dependent and-independent pathways in B-cell chronic lymphocytic leukemia cells: role of protein kinase Cβ M Barragán, M de Frias, D Iglesias-Serret, C Campàs, E Castaño, ... Journal of leukocyte biology 80 (6), 1473-1479, 2006 | 83 | 2006 |
| Activated ERBB2/HER2 licenses sensitivity to apoptosis upon endoplasmic reticulum stress through a PERK-dependent pathway R Martín-Pérez, C Palacios, R Yerbes, A Cano-González, ... Cancer research 74 (6), 1766-1777, 2014 | 70 | 2014 |
| Regulation of the proapoptotic BH3-only protein BIM by glucocorticoids, survival signals and proteasome in chronic lymphocytic leukemia cells D Iglesias-Serret, M De Frias, AF Santidrian, L Coll-Mulet, AM Cosialls, ... Leukemia 21 (2), 281-287, 2007 | 62 | 2007 |
| Multiplex ligation‐dependent probe amplification for detection of genomic alterations in chronic lymphocytic leukaemia L Coll‐Mulet, AF Santidrián, AM Cosialls, D Iglesias‐Serret, M De Frias, ... British journal of haematology 142 (5), 793-801, 2008 | 53 | 2008 |
| Akt inhibitors induce apoptosis in chronic lymphocytic leukemia cells M de Frias, D Iglesias-Serret, AM Cosialls, L Coll-Mulet, AF Santidrián, ... haematologica 94 (12), 1698, 2009 | 50 | 2009 |
| A trifluorinated thiazoline scaffold leading to pro‐apoptotic agents targeting prohibitins A Pérez‐Perarnau, S Preciado, CM Palmeri, C Moncunill‐Massaguer, ... Angewandte Chemie International Edition 53 (38), 10150-10154, 2014 | 48 | 2014 |
| Apoptosis inhibition can be threatening in Aβ-induced neuroinflammation, through promoting cell proliferation A Abdi, H Sadraie, L Dargahi, L Khalaj, A Ahmadiani Neurochemical Research 36, 39-48, 2011 | 41 | 2011 |
| Aspirin induces apoptosis in human leukemia cells independently of NF-κB and MAPKs through alteration of the Mcl-1/Noxa balance D Iglesias-Serret, M Piqué, M Barragán, AM Cosialls, AF Santidrián, ... Apoptosis 15 (2), 219-229, 2010 | 38 | 2010 |
| A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation C Moncunill-Massaguer, J Saura-Esteller, A Pérez-Perarnau, CM Palmeri, ... Oncotarget 6 (39), 41750, 2015 | 36 | 2015 |
| Analysis of apoptosis regulatory genes altered by histone deacetylase inhibitors in chronic lymphocytic leukemia cells A Pérez-Perarnau, L Coll-Mulet, C Rubio-Patiño, D Iglesias-Serret, ... Epigenetics 6 (10), 1228-1235, 2011 | 34 | 2011 |
| The potential anticancer agent PK11195 induces apoptosis irrespective of p53 and ATM status in chronic lymphocytic leukemia cells AF Santidrián, AM Cosialls Castel, L Coll Mulet, D Iglesias i Serret, ... Hematology Journal, 2007, vol. 92, num. 12, p. 1631-1638, 2007 | 33 | 2007 |
| Involvement of both caspase-8 and Noxa-activated pathways in endoplasmic reticulum stress-induced apoptosis in triple-negative breast tumor cells A Cano-González, M Mauro-Lizcano, D Iglesias-Serret, J Gil, ... Cell death & disease 9 (2), 134, 2018 | 32 | 2018 |
| Glycogen synthase kinase-3β is involved in ligand-dependent activation of transcription and cellular localization of the glucocorticoid receptor C Rubio-Patiño, CM Palmeri, A Pérez-Perarnau, AM Cosialls, ... Molecular Endocrinology 26 (9), 1508-1520, 2012 | 27 | 2012 |
| AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts DM González-Gironès, C Moncunill-Massaguer, D Iglesias-Serret, ... Apoptosis 18, 1008-1016, 2013 | 26 | 2013 |
