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Ruchi Lohia
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A streamlined, general approach for computing ligand binding free energies and its application to GPCR-bound cholesterol
R Salari, T Joseph, R Lohia, J Hénin, G Brannigan
Journal of chemical theory and computation 14 (12), 6560-6573, 2018
492018
Comparative metagenome analysis of an Alaskan glacier
S Choudhari, R Lohia, A Grigoriev
Journal of bioinformatics and computational biology 12 (02), 1441003, 2014
232014
Characterization of intrinsically disordered regions in proteins informed by human genetic diversity
SS Ahmed, ZT Rifat, R Lohia, AJ Campbell, AK Dunker, MS Rahman, ...
PLoS Computational Biology 18 (3), e1009911, 2022
132022
Sequence specificity despite intrinsic disorder: How a disease-associated Val/Met polymorphism rearranges tertiary interactions in a long disordered protein
R Lohia, R Salari, G Brannigan
PLoS computational biology 15 (10), e1007390, 2019
112019
A global high-density chromatin interaction network reveals functional long-range and trans-chromosomal relationships
R Lohia, N Fox, J Gillis
Genome Biology 23 (238), 2022
72022
Contiguously hydrophobic sequences are functionally significant throughout the human exome
R Lohia, MEB Hansen, G Brannigan
Proceedings of the National Academy of Sciences 119 (12), e2116267119, 2022
22022
The blobulator: a webtool for identification and visual exploration of hydrophobic modularity in protein sequences
C Pitman, E Santiago-McRae, R Lohia, K Bassi, TT Joseph, MEB Hansen, ...
bioRxiv, 2024.01. 15.575761, 2024
2024
Hydrophobicity Based Sequence Blobulation Approach Captures Functional Modularity: Disease-Associated Mutations are Enriched in Hydrophobic Blobs
R Lohia, M Hansen, GH Brannigan
Biophysical Journal 120 (3), 106a, 2021
2021
Disease Associated Mutations in Intrinsically Disordered Proteins Show Evidence of Enrichment in Hydrophobic Blobs
R Lohia, K Bassi, M Hansen, G Brannigan
Biophysical Journal 118 (3), 215a, 2020
2020
Sequence specificity despite intrinsic disorder: how a disease-associated Val/Met polymorphism shifts tertiary interactions in a long disordered protein
R Lohia, R Salari, G Brannigan
2019
Conformational Effects of a Disease-Associated Hydrophobic-to-Hydrophobic Substitution and Histidine Protonation State Located at the Midpoint of the Intrinsically Disordered …
R Lohia, G Brannigan
Biophysical Journal 116 (3), 179a, 2019
2019
Predicting the effect of genetic variance on the sequence-ensemble relationship of intrinsically disordered proteins
R Lohia
Rutgers University-Camden Graduate School, 2019
2019
Conformational Effects of Various Hydrophobic-to-Hydrophobic Substitution Located at the Midpoint of the Intrinsically Disordered Region of ProBDNF
R Lohia, G Brannigan
Biophysical Journal 114 (3), 591a, 2018
2018
Mechanism Underlying Conformational Effects of a Disease-Associated Hydrophobic-to-Hydrophobic Substitution on an Intrinsically Disordered Region
R Lohia, R Salari, G Brannigan
Biophysical Journal 112 (3), 207a, 2017
2017
Effects of a Structured Domain on the Conformational Ensemble of Disordered Regions in Brain-Derived Neurotrophic Factor
R Lohia, R Salari, G Brannigan
Biophysical Journal 110 (3), 559a, 2016
2016
Prediction of the Effects of the Val66Met Polymorphism and Adjacent Structured Domains on the Conformational Ensemble of an Intrinsically Disordered Protein, Brain-Derived …
R Lohia, R Salari, G Brannigan
Biophysical Journal 108 (2), 386a-387a, 2015
2015
Prediction of the Effects of the Val66Met Polymorphism on the Conformational Ensemble of an Intrinsically Disordered Protein, Brain-Derived Neurotrophic Factor
R Lohia, R Salari, G Brannigan
Biophysical Journal 106 (2), 425a, 2014
2014
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Articles 1–17