Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate CD Knights, J Catania, SD Giovanni, S Muratoglu, R Perez, A Swartzbeck, ... The Journal of cell biology 173 (4), 533-544, 2006 | 341 | 2006 |
Effects of minor groove binding drugs on the interaction of TATA box binding protein and TFIIA with DNA SY Chiang, J Welch, FJ Rauscher III, TA Beerman Biochemistry 33 (23), 7033-7040, 1994 | 211 | 1994 |
Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates JM Belitsky, SJ Leslie, PS Arora, TA Beerman, PB Dervan Bioorganic & medicinal chemistry 10 (10), 3313-3318, 2002 | 161 | 2002 |
Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoechst 33258, and 4', 6-diamidine-2-phenylindole. JM Woynarowski, M McHugh, RD Sigmund, TA Beerman Molecular pharmacology 35 (2), 177-182, 1989 | 155 | 1989 |
DNA strand scission by the antitumor protein neocarzinostatin TA Beerman, IH Goldberg Biochemical and biophysical research communications 59 (4), 1254-1261, 1974 | 141 | 1974 |
Effects of analogs of the DNA minor groove binder Hoechst 33258 on topoisomerase II and I mediated activities TA Beerman, MM McHugh, R Sigmund, JW Lown, KE Rao, Y Bathini Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1131 (1 …, 1992 | 134 | 1992 |
Targeting DNA-binding drugs to sequence-specific transcription factor. DNA complexes. Differential effects of intercalating and minor groove binding drugs. JJ Welch, FJ Rauscher 3rd, TA Beerman Journal of Biological Chemistry 269 (49), 31051-31058, 1994 | 120 | 1994 |
Molecular mechanism of inhibition of survivin transcription by the GC-rich sequence-selective DNA binding antitumor agent, hedamycin: evidence of survivin down-regulation … J Wu, X Ling, D Pan, P Apontes, L Song, P Liang, DC Altieri, T Beerman, ... Journal of Biological Chemistry 280 (10), 9745-9751, 2005 | 114 | 2005 |
Characterization of DNA strand breakage in vitro by the antitumor protein neocarzinostatin R Poon, TA Beermann, IH Goldberg Biochemistry 16 (3), 486-493, 1977 | 105 | 1977 |
Further analysis of the altered secondary structure of superhelical DNA. Sensitivity to methylmercuric hydroxide a chemical probe for unpaired bases TA Beerman, J Lebowitz Journal of molecular biology 79 (3), 451-470, 1973 | 105 | 1973 |
Targeting the Ets Binding Site of the HER2/neuPromoter with Pyrrole-Imidazole Polyamides SY Chiang, RW Burli, CC Benz, L Gawron, GK Scott, PB Dervan, ... Journal of Biological Chemistry 275 (32), 24246-24254, 2000 | 103 | 2000 |
DNA strand scission activity of metalloporphyrins RJ Fiel, TA Beerman, EH Mark, N Datta-Gupta Biochemical and Biophysical Research Communications 107 (3), 1067-1074, 1982 | 88 | 1982 |
The relationship between DNA strand-scission and DNA synthesis inhibition in HeLa cells treated with neocarzinostatin TA Beerman, IH Goldberg Biochimica et Biophysica Acta (BBA)-Nucleic Acids and Protein Synthesis 475 …, 1977 | 82 | 1977 |
Single-strand nicking of DNA in vitro by neocarzinostatin and its possible relationship to the mechanism of drug action TA Beerman, R Poon, IH Goldberg Biochimica et Biophysica Acta (BBA)-Nucleic Acids and Protein Synthesis 475 …, 1977 | 82 | 1977 |
DNA minor groove binding agents interfere with topoisomerase II mediated lesions induced by epipodophyllotoxin derivative VM-26 and acridine derivative m-AMSA in nuclei from … JM Woynarowski, RD Sigmund, TA Beerman Biochemistry 28 (9), 3850-3855, 1989 | 81 | 1989 |
Effect of minor groove binding drugs on mammalian topoisomerase I activity MM McHugh, JM Woynarowski, RD Sigmund, TA Beerman Biochemical pharmacology 38 (14), 2323-2328, 1989 | 79 | 1989 |
Adozelesin triggers DNA damage response pathways and arrests SV40 DNA replication through replication protein A inactivation JS Liu, SR Kuo, MM McHugh, TA Beerman, T Melendy Journal of Biological Chemistry 275 (2), 1391-1397, 2000 | 74 | 2000 |
Netropsin and bis-netropsin analogs as inhibitors of the catalytic activity of mammalian DNA topoisomerase II and topoisomerase cleavable complexes TA Beerman, JM Woynarowski, RD Sigmund, LS Gawron, KE Rao, ... Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1090 (1 …, 1991 | 71 | 1991 |
A Comparison of DNA-Binding Drugs as Inhibitors of E2F1− and Sp1− DNA Complexes and Associated Gene Expression SY Chiang, JC Azizkhan, TA Beerman Biochemistry 37 (9), 3109-3115, 1998 | 70 | 1998 |
DNA crosslinking and biological activity of a hairpin polyamide–chlorambucil conjugate YD Wang, J Dziegielewski, NR Wurtz, B Dziegielewska, PB Dervan, ... Nucleic acids research 31 (4), 1208-1215, 2003 | 69 | 2003 |