Follow
Harikanth Venkannagari
Harikanth Venkannagari
Verified email at uth.tmc.edu
Title
Cited by
Cited by
Year
Structural basis of selective inhibition of human tankyrases
M Narwal, H Venkannagari, L Lehtio
Journal of medicinal chemistry 55 (3), 1360-1367, 2012
1552012
Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity
M Narwal, J Koivunen, T Haikarainen, E Obaji, OE Legala, ...
Journal of medicinal chemistry 56 (20), 7880-7889, 2013
642013
Small-molecule chemical probe rescues cells from mono-ADP-ribosyltransferase ARTD10/PARP10-induced apoptosis and sensitizes cancer cells to DNA damage
H Venkannagari, P Verheugd, J Koivunen, T Haikarainen, E Obaji, ...
Cell chemical biology 23 (10), 1251-1260, 2016
562016
Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors
H Venkannagari, A Fallarero, KLH Feijs, B Lüscher, L Lehtiö
European Journal of Pharmaceutical Sciences 49 (2), 148-156, 2013
522013
para‐Substituted 2‐Phenyl‐3,4‐dihydroquinazolin‐4‐ones As Potent and Selective Tankyrase Inhibitors
T Haikarainen, J Koivunen, M Narwal, H Venkannagari, E Obaji, ...
ChemMedChem 8 (12), 1978-1985, 2013
442013
Structural basis and selectivity of tankyrase inhibition by a Wnt signaling inhibitor WIKI4
T Haikarainen, H Venkannagari, M Narwal, E Obaji, HW Lee, Y Nkizinkiko, ...
PloS one 8 (6), e65404, 2013
382013
Development and structural analysis of adenosine site binding tankyrase inhibitors
T Haikarainen, J Waaler, A Ignatev, Y Nkizinkiko, H Venkannagari, ...
Bioorganic & Medicinal Chemistry Letters 26 (2), 328-333, 2016
292016
Discovery of potent and selective nonplanar tankyrase inhibiting nicotinamide mimics
Y Nkizinkiko, BVSS Kumar, VU Jeankumar, T Haikarainen, J Koivunen, ...
Bioorganic & Medicinal Chemistry 23 (15), 4139-4149, 2015
252015
Inhibition of poly(ADP-ribose) Polymerase Interferes with Trypanosoma cruzi Infection and Proliferation of the Parasite
SC Vilchez Larrea, T Haikarainen, M Narwal, M Schlesinger, ...
Public Library of Science 7 (9), e46063, 2012
252012
4-(Phenoxy) and 4-(benzyloxy) benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10
S Murthy, J Desantis, P Verheugd, MM Maksimainen, H Venkannagari, ...
European journal of medicinal chemistry 156, 93-102, 2018
242018
Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei
M Schlesinger, SC Vilchez Larrea, T Haikarainen, M Narwal, ...
Parasites & vectors 9, 1-15, 2016
162016
Highly conserved molecular features in IgLONs contrast their distinct structural and biological outcomes
H Venkannagari, JM Kasper, A Misra, SA Rush, S Fan, H Lee, H Sun, ...
Journal of molecular biology 432 (19), 5287-5303, 2020
152020
Adenosine analogs bearing phosphate isosteres as human MDO1 ligands
Y Zhang, M Jumppanen, MM Maksimainen, S Auno, Z Awol, L Ghemtio, ...
Bioorganic & Medicinal Chemistry 26 (8), 1588-1597, 2018
102018
[1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes
S Murthy, MG Nizi, MM Maksimainen, S Massari, J Alaviuhkola, BE Lippok, ...
Journal of Medicinal Chemistry 66 (2), 1301-1320, 2023
52023
Self-assembly of the bZIP transcription factor ΔFosB
Z Yin, H Venkannagari, H Lynch, G Aglyamova, M Bhandari, M Machius, ...
Current research in structural biology 2, 1-13, 2020
52020
Architecture of the baculovirus nucleocapsid revealed by cryo-EM
X Jia, Y Gao, Y Huang, L Sun, S Li, H Li, X Zhang, Y Li, J He, W Wu, ...
Nature Communications 14 (1), 7481, 2023
22023
Compounds for use in the treatment of cancer
L Lehtiö, H Venkannagari, B Lüscher, P Verheugd
US Patent 11,096,909, 2021
12021
Predictive modeling and cryo-EM: A synergistic approach to modeling macromolecular structure
MR Corum, H Venkannagari, CF Hryc, ML Baker
Biophysical Journal 123 (4), 435-450, 2024
2024
Compounds for use in the treatment of cancer
L Lehtiö, H Venkannagari, B Lüscher, P Verheugd
US Patent App. 17/380,195, 2021
2021
NEGR1, an IgLON Implicated in Human Obesity, Shares a Conserved 3D Structure and Interaction Mode With Other IgLONs, but Uniquely Impacts Feeding
H Venkannagari, JJ Kasper, A Misra, M Machius, J Hommel, G Rudenko
NEUROPSYCHOPHARMACOLOGY 44 (SUPPL 1), 157-158, 2019
2019
The system can't perform the operation now. Try again later.
Articles 1–20