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Julien Roche
Julien Roche
Verified email at iastate.edu
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Cavities determine the pressure unfolding of proteins
J Roche, JA Caro, DR Norberto, P Barthe, C Roumestand, JL Schlessman, ...
Proceedings of the National Academy of Sciences 109 (18), 6945-6950, 2012
4112012
Monomeric Aβ1–40 and Aβ1–42 Peptides in Solution Adopt Very Similar Ramachandran Map Distributions That Closely Resemble Random Coil
J Roche, Y Shen, JH Lee, J Ying, A Bax
Biochemistry 55 (5), 762-775, 2016
1862016
Homonuclear decoupling for enhancing resolution and sensitivity in NOE and RDC measurements of peptides and proteins
J Ying, J Roche, A Bax
Journal of Magnetic Resonance 241, 97-102, 2014
1302014
Size and sequence and the volume change of protein folding
JB Rouget, T Aksel, J Roche, JL Saldana, AE Garcia, D Barrick, CA Royer
Journal of the American Chemical Society 133 (15), 6020-6027, 2011
1262011
Local unfolding of the HSP27 monomer regulates chaperone activity
TR Alderson, J Roche, HY Gastall, DM Dias, I Pritišanac, J Ying, A Bax, ...
Nature communications 10 (1), 1068, 2019
992019
Lessons from pressure denaturation of proteins
J Roche, CA Royer
Journal of The Royal Society Interface 15 (147), 20180244, 2018
882018
Improved cross validation of a static ubiquitin structure derived from high precision residual dipolar couplings measured in a drug-based liquid crystalline phase
AS Maltsev, A Grishaev, J Roche, M Zasloff, A Bax
Journal of the American Chemical Society 136 (10), 3752-3755, 2014
762014
Effect of internal cavities on folding rates and routes revealed by real-time pressure-jump NMR spectroscopy
J Roche, M Dellarole, JA Caro, DR Norberto, AE Garcia, B Garcia-Moreno, ...
Journal of the American Chemical Society 135 (39), 14610-14618, 2013
732013
ScanFold: an approach for genome-wide discovery of local RNA structural elements—applications to Zika virus and HIV
RJ Andrews, J Roche, WN Moss
PeerJ 6, e6136, 2018
702018
Remodeling of the folding free energy landscape of staphylococcal nuclease by cavity-creating mutations
J Roche, M Dellarole, JA Caro, E Guca, DR Norberto, Y Yang, AE Garcia, ...
Biochemistry 51 (47), 9535-9546, 2012
592012
Impact of hydrostatic pressure on an intrinsically disordered protein: a high‐pressure NMR study of α‐Synuclein
J Roche, J Ying, AS Maltsev, A Bax
ChemBioChem 14 (14), 1754-1761, 2013
542013
Monitoring protein folding through high pressure NMR spectroscopy
J Roche, CA Royer, C Roumestand
Progress in nuclear magnetic resonance spectroscopy 102, 15-31, 2017
502017
Dissociation of the trimeric gp41 ectodomain at the lipid–water interface suggests an active role in HIV-1 Env-mediated membrane fusion
J Roche, JM Louis, A Grishaev, J Ying, A Bax
Proceedings of the National Academy of Sciences 111 (9), 3425-3430, 2014
482014
Structural studies of a rationally selected multi-drug resistant HIV-1 protease reveal synergistic effect of distal mutations on flap dynamics
J Agniswamy, JM Louis, J Roche, RW Harrison, IT Weber
PloS one 11 (12), e0168616, 2016
442016
Structural plasticity of staphylococcal nuclease probed by perturbation with pressure and pH
R Kitahara, K Hata, A Maeno, K Akasaka, MS Chimenti, ...
Proteins: Structure, Function, and Bioinformatics 79 (4), 1293-1305, 2011
342011
Conformation of inhibitor‐free HIV‐1 protease derived from nmr spectroscopy in a weakly oriented solution
J Roche, JM Louis, A Bax
ChemBioChem 16 (2), 214-218, 2015
332015
Probing the Physical Determinants of Thermal Expansion of Folded Proteins
M Dellarole, K Kobayashi, JB Rouget, JA Caro, J Roche, MM Islam, ...
The Journal of Physical Chemistry B 117 (42), 12742-12749, 2013
322013
The Energetics of a Three‐State Protein Folding System Probed by High‐Pressure Relaxation Dispersion NMR Spectroscopy
V Tugarinov, DS Libich, V Meyer, J Roche, GM Clore
Angewandte Chemie International Edition 54 (38), 11157-11161, 2015
292015
Structural, energetic, and dynamic responses of the native state ensemble of staphylococcal nuclease to cavity‐creating mutations
J Roche, JA Caro, M Dellarole, E Guca, CA Royer, E García‐Moreno, ...
Proteins: Structure, Function, and Bioinformatics 81 (6), 1069-1080, 2013
292013
Exploring protein conformational landscapes using high-pressure NMR
J Roche, CA Royer, C Roumestand
Methods in Enzymology 614, 293-320, 2019
272019
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Articles 1–20