Tumor-targeted chlorotoxin-coupled nanoparticles for nucleic acid delivery to glioblastoma cells: a promising system for glioblastoma treatment PM Costa, AL Cardoso, LS Mendonça, A Serani, C Custódia, ... Molecular Therapy-Nucleic Acids 2, 2013 | 117 | 2013 |
Transferrin Receptor-Targeted Liposomes Encapsulating anti-BCR-ABL siRNA or asODN for Chronic Myeloid Leukemia Treatment LS Mendonça, F Firmino, JN Moreira, MC Pedroso de Lima, S Simões Bioconjugate chemistry 21 (1), 157-168, 2010 | 113 | 2010 |
Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype M Conceição, L Mendonça, C Nóbrega, C Gomes, P Costa, H Hirai, ... Biomaterials 82, 124-137, 2016 | 100 | 2016 |
Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice LS Mendonça, C Nobrega, H Hirai, BK Kaspar, L Pereira de Almeida Brain 138 (2), 320-335, 2015 | 92 | 2015 |
Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia C Nóbrega, L Mendonça, A Marcelo, A Lamazière, S Tomé, G Despres, ... Acta Neuropathologica 138, 837-858, 2019 | 62 | 2019 |
Co‐encapsulation of anti‐BCR‐ABL siRNA and imatinib mesylate in transferrin receptor‐targeted sterically stabilized liposomes for chronic myeloid leukemia … LS Mendonça, JN Moreira, MCP de Lima, S Simões Biotechnology and bioengineering 107 (5), 884-893, 2010 | 61 | 2010 |
Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado–Joseph disease C Nobrega, S Carmo-Silva, D Albuquerque, A Vasconcelos-Ferreira, ... Brain 138 (12), 3537-3554, 2015 | 48 | 2015 |
Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado–Joseph disease models A Marcelo, F Brito, S Carmo-Silva, CA Matos, J Alves-Cruzeiro, ... Human Molecular Genetics 28 (1), 51-63, 2019 | 44 | 2019 |
Successes and hurdles in stem cells application and production for brain transplantation D Henriques, R Moreira, J Schwamborn, L Pereira de Almeida, ... Frontiers in Neuroscience 13, 481655, 2019 | 38 | 2019 |
Motor dysfunctions and neuropathology in mouse models of spinocerebellar ataxia type 2: a comprehensive review JMDC Alves-Cruzeiro, L Mendonça, L Pereira de Almeida, C Nóbrega Frontiers in Neuroscience 10, 572, 2016 | 29 | 2016 |
Understanding how birds rebuild fat stores during migration: insights from an experimental study PM Araújo, I Viegas, AD Rocha, A Villegas, JG Jones, L Mendonça, ... Scientific reports 9 (1), 10065, 2019 | 28 | 2019 |
A handbook of gene and cell therapy C Nóbrega, L Mendonça, CA Matos Springer, 2020 | 26 | 2020 |
Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado–Joseph disease models LS Mendonça, C Nóbrega, S Tavino, M Brinkhaus, C Matos, S Tomé, ... Human Molecular Genetics 28 (22), 3691-3703, 2019 | 22 | 2019 |
RNA interference therapy for Machado–Joseph disease: long-term safety profile of lentiviral vectors encoding short hairpin RNAs targeting mutant ataxin-3 C Nobrega, JM Codesso, L Mendonca, L Pereira de Almeida Human Gene Therapy 30 (7), 841-854, 2019 | 21 | 2019 |
Stem cell-based therapies for polyglutamine diseases LS Mendonça, I Onofre, CO Miranda, R Perfeito, C Nóbrega, ... Polyglutamine Disorders, 439-466, 2018 | 15 | 2018 |
Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles M Conceição, L Mendonça, C Nóbrega, C Gomes, P Costa, H Hirai, ... Data in brief 6, 700-705, 2016 | 12 | 2016 |
Extracellular vesicle-based delivery of silencing sequences for the treatment of Machado-Joseph disease/spinocerebellar ataxia type 3 D Rufino-Ramos, PR Albuquerque, K Leandro, V Carmona, IM Martins, ... Molecular Therapy 31 (5), 1275-1292, 2023 | 9 | 2023 |
The stress granule protein G3BP1 alleviates spinocerebellar ataxia-associated deficits R Koppenol, A Conceição, IT Afonso, R Afonso-Reis, RG Costa, S Tomé, ... Brain 146 (6), 2346-2363, 2023 | 8 | 2023 |
Gene therapy strategies: gene augmentation C Nóbrega, L Mendonça, CA Matos, C Nóbrega, L Mendonça, CA Matos A handbook of gene and cell therapy, 117-126, 2020 | 8 | 2020 |
Lysosomal storage disease-associated neuropathy: targeting stable nucleic acid lipid particle (SNALP)-formulated siRnas to the brain as a therapeutic approach MF Coutinho, JI Santos, L S. Mendonça, L Matos, MJ Prata, A S. Jurado, ... International Journal of Molecular Sciences 21 (16), 5732, 2020 | 7 | 2020 |