Identifying drivers in the converging syntenic aneuploidies of spontaneous canine and pediatric high-grade glioma using imaging-based an arrayed CRISPR-Cas9 phenotypic screen SB Amin, A Gujar, E Yi, W Kang, M Costa, G Sjogren, P Gabriel, L Maher, ... Cancer Research 82 (12_Supplement), 3106-3106, 2022 | | 2022 |
Glioma progression is shaped by genetic evolution and microenvironment interactions FS Varn, KC Johnson, J Martinek, JT Huse, MLP Nasrallah, P Wesseling, ... Cell, 2022 | 184 | 2022 |
Live-Cell Imaging Shows Uneven Segregation of Extrachromosomal DNA Elements and Transcriptionally Active Extrachromosomal DNA Hubs in CancerInheritance and Transcriptional … E Yi, AD Gujar, M Guthrie, H Kim, D Zhao, KC Johnson, SB Amin, ... Cancer Discovery 12 (2), 468-483, 2022 | 73 | 2022 |
Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy CJ Terranova, M Tang, M Maitituoheti, AT Raman, AK Ghosh, J Schulz, ... Cell reports 36 (3), 109410, 2021 | 20 | 2021 |
Radiotherapy is associated with a deletion signature that contributes to poor outcomes in patients with cancer E Kocakavuk, KJ Anderson, FS Varn, KC Johnson, SB Amin, E Sulman, ... Nature genetics 53 (7), 1088-1096, 2021 | 94 | 2021 |
Machine Learning Approaches Pertinent to Glioma Classification SB Amin Precision Molecular Pathology of Glioblastoma, 55-66, 2021 | | 2021 |
Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure KC Akdemir, VT Le, JM Kim, S Killcoyne, DA King, YP Lin, Y Tian, A Inoue, ... Nature Genetics 52 (11), 1178-1188, 2020 | 103 | 2020 |
Enhancer reprogramming confers dependence on glycolysis and IGF signaling in KMT2D mutant melanoma M Maitituoheti, EZ Keung, M Tang, L Yan, H Alam, G Han, AK Singh, ... Cell Reports 33 (3), 108293, 2020 | 49 | 2020 |
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers H Kim, NP Nguyen, K Turner, S Wu, AD Gujar, J Luebeck, J Liu, ... Nature genetics 52 (9), 891-897, 2020 | 296 | 2020 |
Sex differences in oncogenic mutational processes SD Prokopec, RX Sun, F Yousif, N Schmitz, F Al-Shahrour, G Atwal, ... Nature Publishing Group UK, 2020 | | 2020 |
KMT2D deficiency impairs super-enhancers to confer a glycolytic vulnerability in lung cancer H Alam, M Tang, M Maitituoheti, SS Dhar, M Kumar, CY Han, CR Ambati, ... Cancer cell 37 (4), 599-617. e7, 2020 | 151 | 2020 |
Comparative molecular life history of spontaneous canine and human gliomas SB Amin, KJ Anderson, CE Boudreau, E Martinez-Ledesma, E Kocakavuk, ... Cancer cell 37 (2), 243-257. e7, 2020 | 67 | 2020 |
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ... Nature 578 (7793), 102-111, 2020 | 501 | 2020 |
Molecular and clonal evolution in recurrent metastatic gliosarcoma KJ Anderson, AC Tan, J Parkinson, M Back, M Kastelan, A Newey, ... Molecular Case Studies 6 (1), a004671, 2020 | 11 | 2020 |
Molecular and clonal evolution in recurrent metastatic gliosarcoma M Kastelan, A Newey, J Brewer, H Wheeler, AL Hudson, SB Amin, ... | | 2020 |
The effects of MicroRNA deregulation on pre-RNA processing network in multiple myeloma S Adamia, I Abiatari, SB Amin, M Fulciniti, S Minvielle, C Li, P Moreau, ... Leukemia 34 (1), 167-179, 2020 | 15 | 2020 |
Longitudinal molecular trajectories of diffuse glioma in adults FP Barthel, KC Johnson, FS Varn, AD Moskalik, G Tanner, E Kocakavuk, ... Nature 576 (7785), 112-120, 2019 | 389 | 2019 |
p53 is a master regulator of proteostasis in SMARCB1-deficient malignant rhabdoid tumors A Carugo, R Minelli, L Sapio, M Soeung, F Carbone, FS Robinson, ... Cancer Cell 35 (2), 204-220. e9, 2019 | 71 | 2019 |
An in vivo screen identifies PYGO2 as a driver for metastatic prostate cancer X Lu, X Pan, CJ Wu, D Zhao, S Feng, Y Zang, R Lee, S Khadka, SB Amin, ... Cancer research 78 (14), 3823-3833, 2018 | 25 | 2018 |
Genomic profiling of canine glioma: comparative analyses with respect to drivers of human glioma SB Amin, JE Martinez-Ledesma, B Boudreau, H Kim, KC Johnson, ... Cancer Research 78 (13 Supplement), 1176-1176, 2018 | 1 | 2018 |