| Synthesis, characterization, and in vitro antimalarial and antitumor activity of new ruthenium (II) complexes of chloroquine CSK Rajapakse, A Martinez, B Naoulou, AA Jarzecki, L Suarez, ... Inorganic chemistry 48 (3), 1122-1131, 2009 | 147 | 2009 |
| Searching for new chemotherapies for tropical diseases: Ruthenium–clotrimazole complexes display high in vitro activity against Leishmania major and Trypanosoma cruzi and low … A Martínez, T Carreon, E Iniguez, A Anzellotti, A Sánchez, M Tyan, ... Journal of medicinal chemistry 55 (8), 3867-3877, 2012 | 124 | 2012 |
| In vitro and in vivo evaluation of water-soluble iminophosphorane ruthenium (II) compounds. A potential chemotherapeutic agent for triple negative breast cancer M Frik, A Martínez, BT Elie, O Gonzalo, D Ramírez de Mingo, M Sanaú, ... Journal of medicinal chemistry 57 (23), 9995-10012, 2014 | 103 | 2014 |
| Synthesis of apoptosis-inducing iminophosphorane organogold (III) complexes and study of their interactions with biomolecular targets N Shaik, A Martinez, I Augustin, H Giovinazzo, A Varela-Ramirez, ... Inorganic chemistry 48 (4), 1577-1587, 2009 | 97 | 2009 |
| Metal–drug synergy: new ruthenium(II) complexes of ketoconazole are highly active against Leishmania major and Trypanosoma cruzi and nontoxic to human or … E Iniguez, A Sánchez, MA Vasquez, A Martínez, J Olivas, A Sattler, ... JBIC Journal of Biological Inorganic Chemistry 18, 779-790, 2013 | 96 | 2013 |
| Interactions of arene–Ru (II)–chloroquine complexes of known antimalarial and antitumor activity with human serum albumin (HSA) and transferrin A Martínez, J Suárez, T Shand, RS Magliozzo, RA Sánchez-Delgado Journal of inorganic biochemistry 105 (1), 39-45, 2011 | 93 | 2011 |
| Effects of noncovalent platinum drug–protein interactions on drug efficacy: use of fluorescent conjugates as probes for drug metabolism BT Benedetti, EJ Peterson, P Kabolizadeh, A Martínez, R Kipping, ... Molecular pharmaceutics 8 (3), 940-948, 2011 | 71 | 2011 |
| Ruthenium (II) arene complexes with chelating chloroquine analogue ligands: synthesis, characterization and in vitro antimalarial activity L Glans, A Ehnbom, C de Kock, A Martínez, J Estrada, PJ Smith, ... Dalton Transactions 41 (9), 2764-2773, 2012 | 69 | 2012 |
| Arene–Ru (II)–chloroquine complexes interact with DNA, induce apoptosis on human lymphoid cell lines and display low toxicity to normal mammalian cells A Martínez, CSK Rajapakse, RA Sánchez-Delgado, A Varela-Ramirez, ... Journal of inorganic biochemistry 104 (9), 967-977, 2010 | 61 | 2010 |
| The mechanism of antimalarial action of the ruthenium(II)–chloroquine complex [RuCl2(CQ)]2 A Martínez, CSK Rajapakse, B Naoulou, Y Kopkalli, L Davenport, ... JBIC Journal of Biological Inorganic Chemistry 13, 703-712, 2008 | 53 | 2008 |
| Analysis of the cytotoxic effects of ruthenium–ketoconazole and ruthenium–clotrimazole complexes on cancer cells E Robles-Escajeda, A Martínez, A Varela-Ramirez, RA Sánchez-Delgado, ... Cell biology and toxicology 29, 431-443, 2013 | 49 | 2013 |
| The mechanism of antimalarial action of [Au (CQ)(PPh3)] PF6: structural effects and increased drug lipophilicity enhance heme aggregation inhibition at lipid/water interfaces M Navarro, W Castro, A Martínez, RAS Delgado Journal of inorganic biochemistry 105 (2), 276-282, 2011 | 45 | 2011 |
| Influence of the position of substituents in the cytotoxic activity of trans platinum complexes with hydroxymethyl pyridines A Martínez, J Lorenzo, MJ Prieto, M Font-Bardia, X Solans, FX Avilés, ... Bioorganic & Medicinal Chemistry 15 (2), 969-979, 2007 | 44 | 2007 |
| The antimalarial activity of Ru–chloroquine complexes against resistant Plasmodium falciparum is related to lipophilicity, basicity, and heme aggregation inhibition ability near … A Martínez, CSK Rajapakse, D Jalloh, C Dautriche, RA Sánchez-Delgado JBIC Journal of Biological Inorganic Chemistry 14, 863-871, 2009 | 42 | 2009 |
| Selective Hydrogenation of Cinnamaldehyde and Other α, β-Unsaturated Substrates Catalyzed by Rhodium and Ruthenium Complexes S Jiménez, JA López, MA Ciriano, C Tejel, A Martinez, ... Organometallics 28 (11), 3193-3202, 2009 | 41 | 2009 |
| Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis PJ Villanueva, A Martinez, ST Baca, RE DeJesus, M Larragoity, ... PLoS One 13 (11), e0206467, 2018 | 37 | 2018 |
| Ruthenium-Clotrimazole complex has significant efficacy in the murine model of cutaneous leishmaniasis E Iniguez, A Varela-Ramirez, A Martínez, CL Torres, ... Acta tropica 164, 402-410, 2016 | 28 | 2016 |
| Probing metal-ion purine interactions at DNA minor-groove sites MA Galindo, D Amantia, A Martinez Martinez, W Clegg, RW Harrington, ... Inorganic chemistry 48 (21), 10295-10303, 2009 | 27 | 2009 |
| Recognition of DNA modified by trans‐[PtCl2NH3(4‐hydroxymethylpyridine)] by tumor suppressor protein p53 and character of DNA adducts of this cytotoxic … K Stehlíková, J Kašpárková, O Nováková, A Martínez, V Moreno, V Brabec The FEBS journal 273 (2), 301-314, 2006 | 26 | 2006 |
| Synthesis, Characterization and Biological Activity of trans‐Platinum(II) and trans‐Platinum(IV) Complexes with 4‐Hydroxymethylpyridine A Martínez, J Lorenzo, MJ Prieto, R De Llorens, M Font‐Bardia, X Solans, ... ChemBioChem 6 (11), 2068-2077, 2005 | 23 | 2005 |
