Pacemaker channel dysfunction in a patient with sinus node disease E Schulze-Bahr, A Neu, P Friederich, UB Kaupp, G Breithardt, O Pongs, ... The Journal of clinical investigation 111 (10), 1537-1545, 2003 | 505 | 2003 |
Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior HC Peters, H Hu, O Pongs, JF Storm, D Isbrandt Nature neuroscience 8 (1), 51-60, 2005 | 437 | 2005 |
Guanidinoacetate methyltransferase deficiency: the first inborn error of creatine metabolism in man. S Stöckler, D Isbrandt, F Hanefeld, B Schmidt, K Von Figura American journal of human genetics 58 (5), 914, 1996 | 259 | 1996 |
Conserved Kv4 N-terminal domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gating R Bähring, J Dannenberg, HC Peters, T Leicher, O Pongs, D Isbrandt Journal of Biological Chemistry 276 (26), 23888-23894, 2001 | 250 | 2001 |
Adenosine receptor antagonists including caffeine alter fetal brain development in mice CG Silva, C Métin, W Fazeli, NJ Machado, S Darmopil, PS Launay, ... Science translational medicine 5 (197), 197ra104-197ra104, 2013 | 183 | 2013 |
Severely altered guanidino compound levels, disturbed body weight homeostasis and impaired fertility in a mouse model of guanidinoacetate N-methyltransferase (GAMT) deficiency A Schmidt, B Marescau, EA Boehm, WKJ Renema, R Peco, A Das, ... Human molecular genetics 13 (9), 905-921, 2004 | 181 | 2004 |
Homoarginine Levels Are Regulated by l-Arginine:Glycine Amidinotransferase and Affect Stroke Outcome: Results From Human and Murine Studies C Choe, D Atzler, PS Wild, AM Carter, RH Böger, F Ojeda, O Simova, ... Circulation 128 (13), 1451-1461, 2013 | 161 | 2013 |
Control of heart rate by cAMP sensitivity of HCN channels J Alig, L Marger, P Mesirca, H Ehmke, ME Mangoni, D Isbrandt Proceedings of the National Academy of Sciences 106 (29), 12189-12194, 2009 | 141 | 2009 |
Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions J Prox, C Bernreuther, H Altmeppen, J Grendel, M Glatzel, R D'Hooge, ... Journal of Neuroscience 33 (32), 12915-12928, 2013 | 140 | 2013 |
Activation of GABAA receptors by guanidinoacetate: a novel pathophysiological mechanism A Neu, H Neuhoff, G Trube, S Fehr, K Ullrich, J Roeper, D Isbrandt Neurobiology of disease 11 (2), 298-307, 2002 | 139 | 2002 |
Reduced inotropic reserve and increased susceptibility to cardiac ischemia/reperfusion injury in phosphocreatine-deficient guanidinoacetate-n-methyltransferase–knockout mice M ten Hove, CA Lygate, A Fischer, JE Schneider, AE Sang, K Hulbert, ... Circulation 111 (19), 2477-2485, 2005 | 137 | 2005 |
Treatment during a vulnerable developmental period rescues a genetic epilepsy SL Marguet, VTQ Le-Schulte, A Merseburg, A Neu, R Eichler, ... Nature medicine 21 (12), 1436-1444, 2015 | 122 | 2015 |
Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents ITO and ISA D Isbrandt, T Leicher, R Waldschütz, X Zhu, U Luhmann, U Michel, ... Genomics 64 (2), 144-154, 2000 | 105 | 2000 |
Coexpression of the KCNA3BGene Product with Kv1. 5 Leads to a Novel A-type Potassium Channel T Leicher, R Bähring, D Isbrandt, O Pongs Journal of Biological Chemistry 273 (52), 35095-35101, 1998 | 104 | 1998 |
N-type inactivation features of Kv4. 2 channel gating M Gebauer, D Isbrandt, K Sauter, B Callsen, A Nolting, O Pongs, ... Biophysical journal 86 (1), 210-223, 2004 | 102 | 2004 |
l-arginine:glycine amidinotransferase deficiency protects from metabolic syndrome C Choe, C Nabuurs, MC Stockebrand, A Neu, P Nunes, F Morellini, ... Human molecular genetics 22 (1), 110-123, 2013 | 98 | 2013 |
Functional roles of Cav1.3, Cav3.1 and HCN channels in automaticity of mouse atrioventricular cells: Insights into the atrioventricular pacemaker mechanism L Marger, P Mesirca, J Alig, A Torrente, S Dübel, B Engeland, S Kanani, ... Channels 5 (3), 251-261, 2011 | 97 | 2011 |
Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake CI Nabuurs, CU Choe, A Veltien, HE Kan, LJC van Loon, RJT Rodenburg, ... The Journal of physiology 591 (2), 571-592, 2013 | 95 | 2013 |
Cardiac arrhythmia induced by genetic silencing of ‘funny’ (f) channels is rescued by GIRK4 inactivation P Mesirca, J Alig, AG Torrente, JC Müller, L Marger, A Rollin, C Marquilly, ... Nature communications 5 (1), 4664, 2014 | 93 | 2014 |
Identification and functional characterization of a novel KCNE2 (MiRP1) mutation that alters HERG channel kinetics D Isbrandt, P Friederich, A Solth, W Haverkamp, A Ebneth, M Borggrefe, ... Journal of molecular medicine 80, 524-532, 2002 | 86 | 2002 |