| Validation of FLIPR membrane potential dye for high throughput screening of potassium channel modulators KL Whiteaker, SM Gopalakrishnan, D Groebe, CC Shieh, U Warrior, ... SLAS Discovery 6 (5), 305-312, 2001 | 128 | 2001 |
| 1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 … Z Chen, SM Gopalakrishnan, MH Bui, NB Soni, U Warrior, EF Johnson, ... Journal of Biological Chemistry 286 (51), 43951-43958, 2011 | 107 | 2011 |
| Structure−Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H4 Receptor Ligands RJ Altenbach, RM Adair, BM Bettencourt, LA Black, SR Fix-Stenzel, ... Journal of medicinal chemistry 51 (20), 6571-6580, 2008 | 102 | 2008 |
| Homogeneous time-resolved fluorescence quenching assay (LANCE) for caspase-3 J Karvinen, P Hurskainen, S Gopalakrishnan, D Burns, U Warrior, ... Journal of biomolecular screening 7 (3), 223-231, 2002 | 91 | 2002 |
| Role of Rho kinase pathway in chondroitin sulfate proteoglycan‐mediated inhibition of neurite outgrowth in PC12 cells SM Gopalakrishnan, N Teusch, C Imhof, MHM Bakker, M Schurdak, ... Journal of neuroscience research 86 (10), 2214-2226, 2008 | 89 | 2008 |
| Structure–Activity studies for a novel series of tricyclic dihydropyrimidines as KATP channel openers (KCOs) I Drizin, MW Holladay, L Yi, HQ Zhang, S Gopalakrishnan, ... Bioorganic & medicinal chemistry letters 12 (11), 1481-1484, 2002 | 86 | 2002 |
| Discovery of 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a Novel Positive Allosteric Modulator of the α7 … R Faghih, SM Gopalakrishnan, JH Gronlien, J Malysz, CA Briggs, ... Journal of medicinal chemistry 52 (10), 3377-3384, 2009 | 72 | 2009 |
| In vitro pharmacological characterization of a novel selective α7 neuronal nicotinic acetylcholine receptor agonist ABT-107 J Malysz, DJ Anderson, JH Grønlien, J Ji, WH Bunnelle, M Håkerud, ... Journal of Pharmacology and Experimental Therapeutics 334 (3), 863-874, 2010 | 67 | 2010 |
| The Alkaloid Conessine and Analogues as Potent Histamine H3 Receptor Antagonists C Zhao, M Sun, YL Bennani, SM Gopalakrishnan, DG Witte, TR Miller, ... Journal of medicinal chemistry 51 (17), 5423-5430, 2008 | 53 | 2008 |
| Utility of large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonists J Chen, MR Lake, RS Sabet, W Niforatos, SD Pratt, SC Cassar, J Xu, ... SLAS Discovery 12 (1), 61-69, 2007 | 53 | 2007 |
| Small molecule IL-36γ antagonist as a novel therapeutic approach for plaque psoriasis V Todorović, Z Su, CB Putman, SJ Kakavas, KM Salte, HA McDonald, ... Scientific reports 9 (1), 9089, 2019 | 47 | 2019 |
| Application of micro arrayed compound screening (pcARCS) to identify inhibitors of caspase-3 SM Gopalakrishnan, J Karvinen, JL Kofron, DJ Burns, U Warrior Journal of biomolecular screening 7 (4), 317-323, 2002 | 43 | 2002 |
| A thallium transport FLIPR-based assay for the identification of KCC2-positive modulators D Zhang, SM Gopalakrishnan, G Freiberg, CS Surowy Journal of Biomolecular screening 15 (2), 177-184, 2010 | 41 | 2010 |
| Novel modes of inhibition of wild-type isocitrate dehydrogenase 1 (IDH1): direct covalent modification of His315 CG Jakob, AK Upadhyay, PL Donner, E Nicholl, SN Addo, W Qiu, C Ling, ... Journal of Medicinal Chemistry 61 (15), 6647-6657, 2018 | 39 | 2018 |
| Structure–activity relationships of non-imidazole H3 receptor ligands. Part 1 R Faghih, W Dwight, R Gentles, K Phelan, TA Esbenshade, L Ireland, ... Bioorganic & medicinal chemistry letters 12 (15), 2031-2034, 2002 | 37 | 2002 |
| Functional characterization of adenosine receptors and coupling to ATP-sensitive K+ channels in Guinea pig urinary bladder smooth muscle SM Gopalakrishnan, SA Buckner, I Milicic, DR Groebe, KL Whiteaker, ... Journal of Pharmacology and Experimental Therapeutics 300 (3), 910-917, 2002 | 37 | 2002 |
| Stable and highly efficient MoS2/Si NWs hybrid heterostructure for photoelectrocatalytic hydrogen evolution reaction G Paulraj, PS Venkatesh, P Dharmaraj, S Gopalakrishnan, K Jeganathan International Journal of Hydrogen Energy 45 (3), 1793-1801, 2020 | 28 | 2020 |
| High-throughput label-free biochemical assays using infrared matrix-assisted desorption electrospray ionization mass spectrometry F Pu, AJ Radosevich, JW Sawicki, D Chang-Yen, NN Talaty, ... Analytical Chemistry 93 (17), 6792-6800, 2021 | 27 | 2021 |
| Thiazoline and oxazoline derivatives and their methods of use R Faghih, GA Gfesser, CL Lynch, M Gopalakrishnan, S Gopalakrishnan, ... US Patent 7,683,084, 2010 | 27 | 2010 |
| Identification of selective dual ROCK1 and ROCK2 inhibitors using structure-based drug design AD Hobson, RA Judge, AL Aguirre, BS Brown, Y Cui, P Ding, ... Journal of medicinal chemistry 61 (24), 11074-11100, 2018 | 25 | 2018 |
