Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production J Blazeck, A Hill, L Liu, R Knight, J Miller, A Pan, P Otoupal, HS Alper Nature communications 5 (1), 3131, 2014 | 569 | 2014 |
Tuning gene expression in Yarrowia lipolytica by a hybrid promoter approach J Blazeck, L Liu, H Redden, H Alper Applied and environmental microbiology 77 (22), 7905-7914, 2011 | 342 | 2011 |
Controlling promoter strength and regulation in Saccharomyces cerevisiae using synthetic hybrid promoters J Blazeck, R Garg, B Reed, HS Alper Biotechnology and bioengineering 109 (11), 2884-2895, 2012 | 340 | 2012 |
Promoter engineering: recent advances in controlling transcription at the most fundamental level J Blazeck, HS Alper Biotechnology journal 8 (1), 46-58, 2013 | 338 | 2013 |
Reversal of indoleamine 2, 3-dioxygenase–mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme TA Triplett, KC Garrison, N Marshall, M Donkor, J Blazeck, C Lamb, ... Nature biotechnology 36 (8), 758-764, 2018 | 231 | 2018 |
Systems metabolic engineering: Genome‐scale models and beyond J Blazeck, H Alper Biotechnology journal 5 (7), 647-659, 2010 | 154 | 2010 |
Metabolic engineering of Yarrowia lipolytica for itaconic acid production J Blazeck, A Hill, M Jamoussi, A Pan, J Miller, HS Alper Metabolic engineering 32, 66-73, 2015 | 144 | 2015 |
Generalizing a hybrid synthetic promoter approach in Yarrowia lipolytica J Blazeck, B Reed, R Garg, R Gerstner, A Pan, V Agarwala, HS Alper Applied microbiology and biotechnology 97, 3037-3052, 2013 | 134 | 2013 |
Metabolic engineering of Saccharomyces cerevisiae for itaconic acid production J Blazeck, J Miller, A Pan, J Gengler, C Holden, M Jamoussi, HS Alper Applied microbiology and biotechnology 98, 8155-8164, 2014 | 111 | 2014 |
Heterologous production of pentane in the oleaginous yeast Yarrowia lipolytica J Blazeck, L Liu, R Knight, HS Alper Journal of Biotechnology 165 (3-4), 184-194, 2013 | 110 | 2013 |
Surveying the lipogenesis landscape in Yarrowia lipolytica through understanding the function of a Mga2p regulatory protein mutant L Liu, K Markham, J Blazeck, N Zhou, D Leon, P Otoupal, HS Alper Metabolic engineering 31, 102-111, 2015 | 72 | 2015 |
Sera antibody repertoire analyses reveal mechanisms of broad and pandemic strain neutralizing responses after human norovirus vaccination LC Lindesmith, JR McDaniel, A Changela, R Verardi, SA Kerr, ... Immunity 50 (6), 1530-1541. e8, 2019 | 71 | 2019 |
Advances in promoter engineering: novel applications and predefined transcriptional control AP Cazier, J Blazeck Biotechnology Journal 16 (10), 2100239, 2021 | 51 | 2021 |
Evolution of an alkane-inducible biosensor for increased responsiveness to short-chain alkanes B Reed, J Blazeck, H Alper Journal of biotechnology 158 (3), 75-79, 2012 | 50 | 2012 |
Immunosuppressive metabolites in tumoral immune evasion: redundancies, clinical efforts, and pathways forward MR Jennings, D Munn, J Blazeck Journal for immunotherapy of cancer 9 (10), 2021 | 24 | 2021 |
Linking yeast Gcn5p catalytic function and gene regulation using a quantitative, graded dominant mutant approach AM Lanza, JJ Blazeck, NC Crook, HS Alper PLoS One 7 (4), e36193, 2012 | 24 | 2012 |
Administration of kynurenine depleting enzymes for tumor therapy G Georgiou, E Stone, N Marshall, J Blazeck, WC Lu US Patent 9,975,959, 2018 | 11 | 2018 |
Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme J Blazeck, CS Karamitros, K Ford, C Somody, A Qerqez, K Murray, ... Nature catalysis 5 (10), 952-967, 2022 | 9 | 2022 |
Compositions and methods for lipid production J Blazeck, A Hill, L Liu, H Alper US Patent 9,896,691, 2018 | 9 | 2018 |
Protein engineering: a driving force toward synthetic immunology JR Cox, J Blazeck Trends in Biotechnology 40 (4), 509-521, 2022 | 3 | 2022 |