| Microglial and macrophage polarization—new prospects for brain repair X Hu, RK Leak, Y Shi, J Suenaga, Y Gao, P Zheng, J Chen Nature Reviews Neurology 11 (1), 56-64, 2015 | 1274 | 2015 |
| Blood-brain barrier dysfunction and recovery after ischemic stroke X Jiang, AV Andjelkovic, L Zhu, T Yang, MVL Bennett, J Chen, RF Keep, ... Progress in neurobiology 163, 144-171, 2018 | 697 | 2018 |
| Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury Y Shi, L Zhang, H Pu, L Mao, X Hu, X Jiang, N Xu, RA Stetler, F Zhang, ... Nature communications 7 (1), 10523, 2016 | 349 | 2016 |
| HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis G Wang, Y Shi, X Jiang, RK Leak, X Hu, Y Wu, H Pu, WW Li, B Tang, ... Proceedings of the National Academy of Sciences 112 (9), 2853-2858, 2015 | 338 | 2015 |
| Oxidative stress and DNA damage after cerebral ischemia: Potential therapeutic targets to repair the genome and improve stroke recovery P Li, RA Stetler, RK Leak, Y Shi, Y Li, W Yu, MVL Bennett, J Chen Neuropharmacology 134, 208-217, 2018 | 254 | 2018 |
| Molecular dialogs between the ischemic brain and the peripheral immune system: dualistic roles in injury and repair C An, Y Shi, P Li, X Hu, Y Gan, RA Stetler, RK Leak, Y Gao, BL Sun, ... Progress in neurobiology 115, 6-24, 2014 | 212 | 2014 |
| Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1 M Zhang, S Wang, L Mao, RK Leak, Y Shi, W Zhang, X Hu, B Sun, G Cao, ... Journal of Neuroscience 34 (5), 1903-1915, 2014 | 193 | 2014 |
| White matter injury and microglia/macrophage polarization are strongly linked with age-related long-term deficits in neurological function after stroke J Suenaga, X Hu, H Pu, Y Shi, SH Hassan, M Xu, RK Leak, RA Stetler, ... Experimental neurology 272, 109-119, 2015 | 173 | 2015 |
| STAT6/Arg1 promotes microglia/macrophage efferocytosis and inflammation resolution in stroke mice W Cai, X Dai, J Chen, J Zhao, M Xu, L Zhang, B Yang, W Zhang, M Rocha, ... JCI insight 4 (20), 2019 | 166 | 2019 |
| Neurobiology of microglial action in CNS injuries: Receptor-mediated signaling mechanisms and functional roles X Hu, AKF Liou, RK Leak, M Xu, C An, J Suenaga, Y Shi, Y Gao, P Zheng, ... Progress in neurobiology 119, 60-84, 2014 | 147 | 2014 |
| Demyelination as a rational therapeutic target for ischemic or traumatic brain injury H Shi, X Hu, RK Leak, Y Shi, C An, J Suenaga, J Chen, Y Gao Experimental neurology 272, 17-25, 2015 | 144 | 2015 |
| Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood–brain barrier disruption after ischemic brain injury Y Shi, X Jiang, L Zhang, H Pu, X Hu, W Zhang, W Cai, Y Gao, RK Leak, ... Proceedings of the National Academy of Sciences 114 (7), E1243-E1252, 2017 | 142 | 2017 |
| Proton-sensitive cation channels and ion exchangers in ischemic brain injury: New therapeutic targets for stroke? T Leng, Y Shi, ZG Xiong, D Sun Progress in neurobiology 115, 189-209, 2014 | 126 | 2014 |
| The interleukin-4/PPARγ signaling axis promotes oligodendrocyte differentiation and remyelination after brain injury Q Zhang, W Zhu, F Xu, X Dai, L Shi, W Cai, H Mu, TK Hitchens, LM Foley, ... PLOS Biology 17 (6), e3000330, 2019 | 111 | 2019 |
| Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke J Wang, Y Shi, L Zhang, F Zhang, X Hu, W Zhang, RK Leak, Y Gao, ... Neurobiology of disease 68, 91-103, 2014 | 103 | 2014 |
| IL-4/STAT6 signaling facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice J Xu, Z Chen, F Yu, H Liu, C Ma, D Xie, X Hu, RK Leak, SHY Chou, ... Proceedings of the National Academy of Sciences 117 (51), 32679-32690, 2020 | 101 | 2020 |
| T cell–derived interleukin (IL)-21 promotes brain injury following stroke in mice BDS Clarkson, C Ling, Y Shi, MG Harris, A Rayasam, D Sun, MS Salamat, ... Journal of Experimental Medicine 211 (4), 595-604, 2014 | 101 | 2014 |
| Inhibition of WNK3 Kinase Signaling Reduces Brain Damage and Accelerates Neurological Recovery After Stroke G Begum, H Yuan, KT Kahle, L Li, S Wang, Y Shi, BE Shmukler, SS Yang, ... Stroke 46 (7), 1956-1965, 2015 | 99 | 2015 |
| In Vivo Expansion of Regulatory T cells with IL-2/IL-2 Antibody Complex Protects against Transient Ischemic Stroke H Zhang, Y Xia, Q Ye, F Yu, W Zhu, P Li, Z Wei, Y Yang, Y Shi, ... Journal of Neuroscience 38 (47), 10168-10179, 2018 | 88 | 2018 |
| Upregulation of NHE1 protein expression enables glioblastoma cells to escape TMZ-mediated toxicity via increased H+ extrusion, cell migration and survival D Cong, W Zhu, Y Shi, KB Pointer, PA Clark, H Shen, JS Kuo, S Hu, ... Carcinogenesis 35 (9), 2014-2024, 2014 | 86 | 2014 |
Jun ChenUniversity of PittsburghVerified email at upmc.edu
