Extracellular vesicles from Sporothrix brasiliensis are an important virulence factor that induce an increase in fungal burden in experimental sporotrichosis MAK Ikeda, JRFA De Almeida, GP Jannuzzi, A Cronemberger-Andrade, ... Frontiers in microbiology 9, 370379, 2018 | 91 | 2018 |
The current drug discovery landscape for trypanosomiasis and leishmaniasis: Challenges and strategies to identify drug targets F Altamura, R Rajesh, CMC Catta‐Preta, NS Moretti, I Cestari Drug development research 83 (2), 225-252, 2022 | 73 | 2022 |
A Membrane-bound eIF2 Alpha Kinase Located in Endosomes Is Regulated by Heme and Controls Differentiation and ROS Levels in Trypanosoma cruzi L da Silva Augusto, NS Moretti, TCP Ramos, TCL de Jesus, M Zhang, ... PLoS pathogens 11 (2), e1004618, 2015 | 56 | 2015 |
Chromatin Proteomics Reveals Variable Histone Modifications during the Life Cycle of Trypanosoma cruzi TCL de Jesus, VS Nunes, MC Lopes, DE Martil, LK Iwai, NS Moretti, ... Journal of proteome research 15 (6), 2039-2051, 2016 | 48 | 2016 |
Comparative proteomic analysis of lysine acetylation in Trypanosomes NS Moretti, I Cestari, A Anupama, K Stuart, S Schenkman Journal of proteome research 17 (1), 374-385, 2018 | 46 | 2018 |
Characterization of Trypanosoma cruzi sirtuins as possible drug targets for Chagas disease NS Moretti, L da Silva Augusto, TM Clemente, RPP Antunes, N Yoshida, ... Antimicrobial agents and chemotherapy 59 (8), 4669-4679, 2015 | 44 | 2015 |
Chemical Constituents of Anacardium occidentale as Inhibitors of Trypanosoma cruzi Sirtuins T Matutino Bastos, H Mannochio Russo, N Silvio Moretti, S Schenkman, ... Molecules 24 (7), 1299, 2019 | 38 | 2019 |
Preclinical gold complexes as oral drug candidates to treat leishmaniasis are potent trypanothione reductase inhibitors LG Tunes, RE Morato, A Garcia, V Schmitz, M Steindel, ... ACS Infectious Diseases 6 (5), 1121-1139, 2020 | 36 | 2020 |
Trypanosoma cruzi NS Moretti, RA Mortara, S Schenkman Trends in Parasitology 36 (4), 2, 2020 | 35 | 2020 |
Nuclear subcompartments: an overview VS Nunes, NS Moretti Cell biology international 41, 2-7, 2017 | 32 | 2017 |
Catalase expression impairs oxidative stress-mediated signalling in Trypanosoma cruzi ACG Freire, CL Alves, GR Goes, BC Resende, NS Moretti, VS Nunes, ... Parasitology 144 (11), 1498-1510, 2017 | 27 | 2017 |
Chemogenetic characterization of inositol phosphate metabolic pathway reveals druggable enzymes for targeting kinetoplastid parasites I Cestari, P Haas, NS Moretti, S Schenkman, K Stuart Cell chemical biology 23 (5), 608-617, 2016 | 26 | 2016 |
Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures IQH Phan, DR Davies, NS Moretti, D Shanmugam, I Cestari, A Anupama, ... Acta Crystallographica Section F: Structural Biology Communications 71 (5 …, 2015 | 24 | 2015 |
Expression of non-acetylatable lysines 10 and 14 of histone H4 impairs transcription and replication in Trypanosoma cruzi TCP Ramos, VS Nunes, SC Nardelli, B dos Santos Pascoalino, ... Molecular and biochemical parasitology 204 (1), 1-10, 2015 | 23 | 2015 |
Chromatin modifications in trypanosomes due to stress NS Moretti, S Schenkman Cellular microbiology 15 (5), 709-717, 2013 | 18 | 2013 |
Effect of lysine acetylation on the regulation of Trypanosoma brucei glycosomal aldolase activity AB Leite, AAS Gomes, AC de Castro Nascimento de Sousa, ... Biochemical Journal, 2020 | 15 | 2020 |
Toxoplasma gondii Chitinase Induces Macrophage Activation F Almeida, A Sardinha-Silva, TA da Silva, AM Pessoni, CF Pinzan, ... PLoS One 10 (12), e0144507, 2015 | 15 | 2015 |
Disruption of active trans-sialidase genes impairs egress from mammalian host cells and generates highly attenuated Trypanosoma cruzi parasites GA Burle-Caldas, NSA Dos Santos, JT de Castro, FLB Mugge, ... MBio 13 (1), e03478-21, 2022 | 11 | 2022 |
Deregulation of Ikaros expression in B-1 cells: New insights in the malignant transformation to chronic lymphocytic leukemia PAF Oliveira VC, Lacerda MP, Moraes BBM, Gomes CP, Maricato JT, Souza OF ... Journal Leukocyte Biology 106, 2019 | 11 | 2019 |
Cyclophilin 19 secreted in the host cell cytosol by Trypanosoma cruzi promotes ROS production required for parasite growth GP Dos Santos, FM Abukawa, N Souza‐Melo, LM Alcântara, ... Cellular microbiology 23 (4), e13295, 2021 | 10 | 2021 |