| Tear cathepsin S as a candidate biomarker for Sjögren's syndrome SF Hamm‐Alvarez, SR Janga, MC Edman, S Madrigal, M Shah, ... Arthritis & Rheumatology 66 (7), 1872-1881, 2014 | 119 | 2014 |
| Elastin-based protein polymer nanoparticles carrying drug at both corona and core suppress tumor growth in vivo P Shi, S Aluri, YA Lin, M Shah, M Edman, J Dhandhukia, H Cui, ... Journal of controlled release 171 (3), 330-338, 2013 | 116 | 2013 |
| Increased expression of cathepsins and obesity-induced proinflammatory cytokines in lacrimal glands of male NOD mouse X Li, K Wu, M Edman, K Schenke-Layland, M MacVeigh-Aloni, SR Janga, ... Investigative ophthalmology & visual science 51 (10), 5019-5029, 2010 | 74 | 2010 |
| Rapamycin eye drops suppress lacrimal gland inflammation in a murine model of Sjögren's syndrome M Shah, MC Edman, SR Janga, F Yarber, Z Meng, W Klinngam, ... Investigative ophthalmology & visual science 58 (1), 372-385, 2017 | 65 | 2017 |
| Lacritin-mediated regeneration of the corneal epithelia by protein polymer nanoparticles W Wang, J Despanie, P Shi, MC Edman, YA Lin, H Cui, M Heur, ME Fini, ... Journal of Materials Chemistry B 2 (46), 8131-8141, 2014 | 63 | 2014 |
| Oligomeric α-synuclein is increased in basal tears of Parkinson’s patients SF Hamm-Alvarez, CT Okamoto, SR Janga, D Feigenbaum, MC Edman, ... Biomarkers in medicine 13 (11), 941-952, 2019 | 56 | 2019 |
| Increased Cathepsin S activity associated with decreased protease inhibitory capacity contributes to altered tear proteins in Sjögren’s Syndrome patients MC Edman, SR Janga, Z Meng, M Bechtold, AF Chen, C Kim, L Naman, ... Scientific reports 8 (1), 11044, 2018 | 55 | 2018 |
| Delivery of bone marrow-derived mesenchymal stem cells improves tear production in a mouse model of Sjögren’s syndrome HS Aluri, M Samizadeh, MC Edman, DR Hawley, HL Armaos, SR Janga, ... Stem cells international 2017, 2017 | 51 | 2017 |
| Application of advances in endocytosis and membrane trafficking to drug delivery Y Ju, H Guo, M Edman, SF Hamm-Alvarez Advanced drug delivery reviews 157, 118-141, 2020 | 50 | 2020 |
| Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome Z Meng, MC Edman, PY Hsueh, CY Chen, W Klinngam, T Tolmachova, ... American journal of physiology-Cell physiology 310 (11), C942-C954, 2016 | 30 | 2016 |
| Levels of oligomeric α-Synuclein in reflex tears distinguish Parkinson's disease patients from healthy controls SF Hamm-Alvarez, SR Janga, MC Edman, D Feigenbaum, D Freire, ... Biomarkers in medicine 13 (17), 1447-1457, 2019 | 29 | 2019 |
| Inhibition of cathepsin S reduces lacrimal gland inflammation and increases tear flow in a mouse model of Sjögren’s syndrome W Klinngam, SR Janga, C Lee, Y Ju, F Yarber, M Shah, H Guo, D Wang, ... Scientific reports 9 (1), 9559, 2019 | 29 | 2019 |
| A Rab11a-enriched subapical membrane compartment regulates a cytoskeleton-dependent transcytotic pathway in secretory epithelial cells of the lacrimal gland S Xu, M Edman, MS Kothawala, G Sun, L Chiang, A Mircheff, L Zhu, ... Journal of Cell Science 124 (20), 3503-3514, 2011 | 29 | 2011 |
| Cathepsin S alters the expression of pro-inflammatory cytokines and MMP-9, partially through protease—activated receptor-2, in human corneal epithelial cells W Klinngam, R Fu, SR Janga, MC Edman, SF Hamm-Alvarez International Journal of Molecular Sciences 19 (11), 3530, 2018 | 27 | 2018 |
| A novel elastin-like polypeptide drug carrier for cyclosporine A improves tear flow in a mouse model of Sjögren's syndrome H Guo, C Lee, M Shah, SR Janga, MC Edman, W Klinngam, ... Journal of controlled release 292, 183-195, 2018 | 26 | 2018 |
| Interferon-γ treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of … Z Meng, W Klinngam, MC Edman, SF Hamm-Alvarez PloS one 12 (9), e0184781, 2017 | 26 | 2017 |
| Tear proteases and protease inhibitors: potential biomarkers and disease drivers in ocular surface disease R Fu, W Klinngam, M Heur, MC Edman, SF Hamm-Alvarez Eye & contact lens 46, S70-S83, 2020 | 25 | 2020 |
| Characterization of β-hexosaminidase secretion in rabbit lacrimal gland SV Andersson, MC Edman, A Bekmezian, J Holmberg, AK Mircheff, ... Experimental eye research 83 (5), 1081-1088, 2006 | 25 | 2006 |
| Tear-mediated delivery of nanoparticles through transcytosis of the lacrimal gland PY Hsueh, MC Edman, G Sun, P Shi, S Xu, Y Lin, H Cui, ... Journal of controlled release 208, 2-13, 2015 | 24 | 2015 |
| Longitudinal analysis of tear cathepsin S activity levels in male non-obese diabetic mice suggests its potential as an early stage biomarker of Sjögren’s Syndrome SR Janga, M Shah, Y Ju, Z Meng, MC Edman, SF Hamm-Alvarez Biomarkers 24 (1), 91-102, 2019 | 21 | 2019 |
Sarah Hamm-AlvarezProfessor of Ophthalmology, USCVerified email at usc.edu
