Estrogen receptor β inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest S Paruthiyil, H Parmar, V Kerekatte, GR Cunha, GL Firestone, DC Leitman Cancer research 64 (1), 423-428, 2004 | 768 | 2004 |
Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression A Cvoro, C Tzagarakis-Foster, D Tatomer, S Paruthiyil, MS Fox, ... Molecular cell 21 (4), 555-564, 2006 | 215 | 2006 |
Differential response of estrogen receptor subtypes to 1, 3-diarylindene and 2, 3-diarylindene ligands NJ Clegg, S Paruthiyil, DC Leitman, TS Scanlan Journal of medicinal chemistry 48 (19), 5989-6003, 2005 | 137 | 2005 |
Regulation of specific target genes and biological responses by estrogen receptor subtype agonists DC Leitman, S Paruthiyil, OI Vivar, EF Saunier, CB Herber, I Cohen, ... Current opinion in pharmacology 10 (6), 629-636, 2010 | 131 | 2010 |
Targeted expression of a dominant-negative fibroblast growth factor (FGF) receptor in gonadotropin-releasing hormone (GnRH) neurons reduces FGF responsiveness and the size of … PS Tsai, SM Moenter, HR Postigo, M El Majdoubi, TR Pak, JC Gill, ... Molecular endocrinology 19 (1), 225-236, 2005 | 124 | 2005 |
Selective activation of estrogen receptor-β transcriptional pathways by an herbal extract A Cvoro, S Paruthiyil, JO Jones, C Tzagarakis-Foster, NJ Clegg, ... Endocrinology 148 (2), 538-547, 2007 | 114 | 2007 |
Role of the cAMP signaling pathway in the regulation of gonadotropin-releasing hormone secretion in GT1 cells EA Vitalis, JL Costantin, PS Tsai, H Sakakibara, S Paruthiyil, T Iiri, ... Proceedings of the National Academy of Sciences 97 (4), 1861-1866, 2000 | 97 | 2000 |
Lepromatous leprosy patients show T helper 1‐like cytokine profile with differential expression of interleukin‐10 during type 1 and 2 reactions SREENIVASAN, MISRA, WILFRED, NATH Immunology 95 (4), 529-536, 1998 | 88 | 1998 |
Drug and cell type-specific regulation of genes with different classes of estrogen receptor β-selective agonists S Paruthiyil, A Cvoro, X Zhao, Z Wu, Y Sui, RE Staub, S Baggett, ... PloS one 4 (7), e6271, 2009 | 82 | 2009 |
Estrogen receptor β causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2 S Paruthiyil, A Cvoro, M Tagliaferri, I Cohen, E Shtivelman, DC Leitman Breast cancer research and treatment 129, 777-784, 2011 | 77 | 2011 |
Cross talk between glucocorticoid and estrogen receptors occurs at a subset of proinflammatory genes A Cvoro, C Yuan, S Paruthiyil, OH Miller, KR Yamamoto, DC Leitman The Journal of Immunology 186 (7), 4354-4360, 2011 | 61 | 2011 |
Tissue-specific regulation of genes by estrogen receptors DC Leitman, S Paruthiyil, C Yuan, CB Herber, M Olshansky, M Tagliaferri, ... Seminars in reproductive medicine 30 (01), 14-22, 2012 | 37 | 2012 |
Phosphodiesterase expression targeted to gonadotropin-releasing hormone neurons inhibits luteinizing hormone pulses in transgenic rats S Paruthiyil, ME Majdoubi, M Conti, RI Weiner Proceedings of the National Academy of Sciences 99 (26), 17191-17196, 2002 | 33 | 2002 |
Sexually dimorphic metabolic responses mediated by CRF2 receptor during nutritional stress in mice S Paruthiyil, S Hagiwara, K Kundassery, A Bhargava Biology of sex Differences 9, 1-16, 2018 | 29 | 2018 |
Gastric corticotropin-releasing factor influences mast cell infiltration in a rat model of functional dyspepsia S Hagiwara, E Kaushal, S Paruthiyil, PJ Pasricha, B Hasdemir, ... PLoS One 13 (9), e0203704, 2018 | 28 | 2018 |
Unliganded estrogen receptor-β regulation of genes is inhibited by tamoxifen N Levy, S Paruthiyil, X Zhao, OI Vivar, EF Saunier, C Griffin, M Tagliaferri, ... Molecular and cellular endocrinology 315 (1-2), 201-207, 2010 | 26 | 2010 |
Sex-and corticotropin-releasing factor receptor 2-dependent actions of urocortin 1 during inflammation B Hasdemir, P Mhaske, S Paruthiyil, EA Garnett, MB Heyman, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2016 | 25 | 2016 |
Role of cAMP signaling in the mediation of dopamine-induced stimulation of GnRH secretion via D1 dopamine receptors in GT1-7 cells H Yoshida, S Paruthiyil, P Butler, RI Weiner Neuroendocrinology 80 (1), 2-10, 2004 | 16 | 2004 |
Polyclonal regulatory T cell manufacturing under cGMP: a decade of experience J Balcerek, BR Shy, AL Putnam, LM Masiello, A Lares, F Dekovic, ... Frontiers in Immunology 12, 744763, 2021 | 13 | 2021 |
Functional GLP-1R antibodies identified from a synthetic GPCR-focused library demonstrate potent blood glucose control Q Liu, P Garg, B Hasdemir, L Wang, E Tuscano, E Sever, E Keane, ... MAbs 13 (1), 1893425, 2021 | 8 | 2021 |