Follow
Alex Compton, PhD
Alex Compton, PhD
National Cancer Institute (NCI/NIH)
Verified email at nih.gov - Homepage
Title
Cited by
Cited by
Year
Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control
SA Migueles, CM Osborne, C Royce, AA Compton, RP Joshi, KA Weeks, ...
Immunity 29 (6), 1009-1021, 2008
6552008
IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread
AA Compton, T Bruel, F Porrot, A Mallet, M Sachse, M Euvrard, C Liang, ...
Cell Host & Microbe 16 (6), 736-747, 2014
2322014
Opposing activities of IFITM proteins in SARS-CoV-2 infection
G Shi, AD Kenney, E Kudryashova, A Zani, L Zhang, KK Lai, ...
The EMBO Journal, 2020
1992020
Zika virus induces massive cytoplasmic vacuolization and paraptosis‐like death in infected cells
B Monel*, AA Compton*, T Bruel, S Amraoui, J Burlaud‐Gaillard, N Roy, ...
The EMBO Journal 36, 1653-1668, 2017
1402017
The host restriction factor APOBEC3G and retroviral Vif protein coevolve due to ongoing genetic conflict
AA Compton, VM Hirsch, M Emerman
Cell Host & Microbe 11 (1), 91-98, 2012
1212012
More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins
G Shi, O Schwartz, AA Compton
Retrovirology 14 (1), 1-11, 2017
1172017
IFITM3 requires an amphipathic helix for antiviral activity
NM Chesarino, AA Compton, TM McMichael, AD Kenney, L Zhang, ...
EMBO Reports, e201744100, 2017
1102017
Convergence and divergence in the evolution of the APOBEC3G-Vif interaction reveal ancient origins of simian immunodeficiency viruses
AA Compton, M Emerman
PLOS Pathogens 9 (1), e1003135, 2013
1092013
Natural mutations in IFITM3 modulate post‐translational regulation and toggle antiviral specificity
AA Compton, N Roy, F Porrot, A Billet, N Casartelli, JS Yount, C Liang, ...
EMBO Reports 17 (11), 1657-1671, 2016
952016
Host gene evolution traces the evolutionary history of ancient primate lentiviruses
AA Compton, HS Malik, M Emerman
Philosophical Transactions of the Royal Society: B 368 (1626), 20120496, 2013
892013
Lessons in self-defence: inhibition of virus entry by intrinsic immunity
S Majdoul, AA Compton
Nature Reviews Immunology 22 (6), 339-352, 2021
772021
mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3
G Shi, S Ozog, BE Torbett, AA Compton
Proceedings of the National Academy of Sciences 115 (43), E10069-E10078, 2018
732018
Homology-guided identification of a conserved motif linking the antiviral functions of IFITM3 to its oligomeric state
K Rahman, CA Coomer, S Majdoul, S Ding, S Padilla-Parra, AA Compton
eLife 9, e58537, 2020
532020
They might be giants: does syncytium formation sink or spread HIV infection?
AA Compton, O Schwartz
PLOS Pathogens 13 (2), e1006099, 2017
532017
The hormonal herbicide, 2, 4-dichlorophenoxyacetic acid, inhibits Xenopus oocyte maturation by targeting translational and post-translational mechanisms
AM LaChapelle, ML Ruygrok, ME Toomer, JJ Oost, ML Monnie, ...
Reproductive Toxicology 23 (1), 20-31, 2007
512007
Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion
CA Coomer, I Carlon-Andres, M Iliopoulou, ML Dustin, EB Compeer, ...
PLOS Pathogens 16 (2), e1008359, 2020
352020
Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes
S Ozog, ND Timberlake, K Hermann, O Garijo, KG Haworth, G Shi, ...
Blood 134 (16), 1298-1311, 2019
322019
On the whereabouts of HIV-1 cellular entry and its fusion ports
GM Jakobsdottir, M Iliopoulou, R Nolan, L Alvarez, AA Compton, ...
Trends in Molecular Medicine 23 (10), 932-944, 2017
302017
Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2
G Shi, AI Chiramel, S Majdoul, KK Lai, T Dempsey, A Kenney, A Zani, ...
Journal of Clinical Investigation 132 (24), e160766, 2022
292022
IFITM3 reduces retroviral Envelope abundance and function and is counteracted by glycoGag
YS Ahi, D Yimer, G Shi, S Majdoul, K Rahman, A Rein, AA Compton
mBio 11 (1), e03088-19, 2020
272020
The system can't perform the operation now. Try again later.
Articles 1–20