| Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail E Schönbrunn, S Eschenburg, WA Shuttleworth, JV Schloss, N Amrhein, ... Proceedings of the National Academy of Sciences 98 (4), 1376-1380, 2001 | 688 | 2001 |
| The crystal structure of dimeric kinesin and implications for microtubule-dependent motility F Kozielski, S Sack, A Marx, M Thormählen, E Schönbrunn, V Biou, ... Cell 91 (7), 985-994, 1997 | 532 | 1997 |
| Molecular basis for the herbicide resistance of Roundup Ready crops T Funke, H Han, ML Healy-Fried, M Fischer, E Schönbrunn Proceedings of the National Academy of Sciences 103 (35), 13010-13015, 2006 | 469 | 2006 |
| Acetyl-lysine binding site of bromodomain-containing protein 4 (BRD4) interacts with diverse kinase inhibitors SWJ Ember, JY Zhu, SH Olesen, MP Martin, A Becker, N Berndt, GI Georg, ... ACS chemical biology 9 (5), 1160-1171, 2014 | 240 | 2014 |
| Molecular basis of glyphosate resistance–different approaches through protein engineering L Pollegioni, E Schonbrunn, D Siehl The FEBS journal 278 (16), 2753-2766, 2011 | 237 | 2011 |
| Structural basis for the interaction of the fluorescence probe 8-anilino-1-naphthalene sulfonate (ANS) with the antibiotic target MurA E Schönbrunn, S Eschenburg, K Luger, W Kabsch, N Amrhein Proceedings of the National Academy of Sciences 97 (12), 6345-6349, 2000 | 217 | 2000 |
| Discovery of a potential allosteric ligand binding site in CDK2 S Betzi, R Alam, M Martin, DJ Lubbers, H Han, SR Jakkaraj, GI Georg, ... ACS chemical biology 6 (5), 492-501, 2011 | 186 | 2011 |
| Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation K Mahajan, D Coppola, S Challa, B Fang, YA Chen, W Zhu, AS Lopez, ... PloS one 5 (3), e9646, 2010 | 184 | 2010 |
| Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation K Doi, R Li, SS Sung, H Wu, Y Liu, W Manieri, G Krishnegowda, A Awwad, ... Journal of Biological Chemistry 287 (13), 10224-10235, 2012 | 181 | 2012 |
| Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX J Phan, Z Li, A Kasprzak, B Li, S Sebti, W Guida, E Schönbrunn, J Chen Journal of biological chemistry 285 (3), 2174-2183, 2010 | 175 | 2010 |
| Structural basis of glyphosate resistance resulting from the double mutation Thr97→ Ile and Pro101→ Ser in 5-enolpyruvylshikimate-3-phosphate synthase from Escherichia coli T Funke, Y Yang, H Han, M Healy-Fried, S Olesen, A Becker, ... Journal of Biological Chemistry 284 (15), 9854-9860, 2009 | 172 | 2009 |
| Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release S Eschenburg, M Priestman, E Schönbrunn Journal of Biological Chemistry 280 (5), 3757-3763, 2005 | 169 | 2005 |
| Cyclin-dependent kinase inhibitor dinaciclib interacts with the acetyl-lysine recognition site of bromodomains MP Martin, SH Olesen, GI Georg, E Schönbrunn ACS chemical biology 8 (11), 2360-2365, 2013 | 163 | 2013 |
| RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer RA Patel, KD Forinash, R Pireddu, Y Sun, N Sun, MP Martin, ... Cancer research 72 (19), 5025-5034, 2012 | 158 | 2012 |
| How the mutation glycine96 to alanine confers glyphosate insensitivity to 5-enolpyruvyl shikimate-3-phosphate synthase from Escherichia coli S Eschenburg, ML Healy, MA Priestman, GH Lushington, E Schönbrunn Planta 216, 129-135, 2002 | 149 | 2002 |
| Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin E Schönbrunn, S Sack, S Eschenburg, A Perrakis, F Krekel, N Amrhein, ... Structure 4 (9), 1065-1075, 1996 | 141 | 1996 |
| The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane N Berndt, H Yang, B Trinczek, S Betzi, Z Zhang, B Wu, NJ Lawrence, ... Cell Death & Differentiation 17 (11), 1795-1804, 2010 | 122 | 2010 |
| Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase ML Healy-Fried, T Funke, MA Priestman, H Han, E Schonbrunn Journal of Biological Chemistry 282 (45), 32949-32955, 2007 | 116 | 2007 |
| A new view of the mechanisms of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-phosphate synthase (AroA) derived from X-ray structures of … S Eschenburg, W Kabsch, ML Healy, E Schönbrunn Journal of Biological Chemistry 278 (49), 49215-49222, 2003 | 111 | 2003 |
| Fluorinated Aromatic Amino Acids Are Sensitive 19F NMR Probes for Bromodomain-Ligand Interactions NK Mishra, AK Urick, SWJ Ember, E Schönbrunn, WC Pomerantz ACS Chemical Biology 9 (12), 2755-2760, 2014 | 92 | 2014 |
