CRISPR-Cas9 gene therapy for Duchenne muscular dystrophy CH Mbakam, G Lamothe, G Tremblay, JP Tremblay Neurotherapeutics 19 (3), 931-941, 2022 | 30 | 2022 |
Therapeutic strategies for dystrophin replacement in Duchenne muscular dystrophy C Happi Mbakam, G Lamothe, JP Tremblay Frontiers in Medicine 9, 859930, 2022 | 29 | 2022 |
Prime editing permits the introduction of specific mutations in the gene responsible for duchenne muscular dystrophy C Happi Mbakam, J Rousseau, G Tremblay, P Yameogo, JP Tremblay International Journal of Molecular Sciences 23 (11), 6160, 2022 | 20 | 2022 |
Insertion of the Icelandic mutation (A673T) by prime editing: a potential preventive treatment for familial and sporadic Alzheimer's disease G Tremblay, J Rousseau, CH Mbakam, JP Tremblay The CRISPR Journal 5 (1), 109-122, 2022 | 19 | 2022 |
Prime editing optimized RTT permits the correction of the c. 8713C> T mutation in DMD gene CH Mbakam, J Rousseau, Y Lu, A Bigot, K Mamchaoui, V Mouly, ... Molecular Therapy-Nucleic Acids 30, 272-285, 2022 | 13 | 2022 |
Specific mutations in genes responsible for Alzheimer and for Duchenne muscular dystrophy introduced by base editing and PRIME editing J Rousseau, CH Mbakam, A Guyon, G Tremblay, FG Begin, JP Tremblay BioRxiv, 2020.07. 31.230565, 2020 | 11 | 2020 |
Improvements of nuclease and nickase gene modification techniques for the treatment of genetic diseases Y Lu, C Happi Mbakam, B Song, E Bendavid, JP Tremblay Frontiers in Genome Editing 4, 892769, 2022 | 6 | 2022 |
Gene therapy for Duchenne muscular dystrophy: an update on the latest clinical developments C Happi Mbakam, JP Tremblay Expert Review of Neurotherapeutics 23 (10), 905-920, 2023 | 2 | 2023 |
Cytokine levels of interleukin-2 and 7 amongst antiretroviral therapy success and failure HIV patients attending the University Teaching Hospital, Yaoundé, Cameroon GM Ikomey, CH Mbakam, MCO Assoumou, JG Brandon, M Mesembe, ... International journal of biological and chemical sciences 14 (1), 11-19, 2020 | 2 | 2020 |
Prime editing strategies to mediate exon skipping in DMD gene C Happi Mbakam, J Roustant, J Rousseau, P Yameogo, Y Lu, A Bigot, ... Frontiers in Medicine 10, 1128557, 2023 | 1 | 2023 |
Development of a therapeutic approach for hereditary diseases with prime editing: A study on Alzheimer's disease G Tremblay, J Rousseau, C Happi‐Mbakam, A Guyon, JP Tremblay Alzheimer's & Dementia 17, e050660, 2021 | 1 | 2021 |
Potential of Interleukin 7 and CD4/CD8 Ratio as Markers of Immune Reconstitution in HIV Patients on Antiretroviral Therapy in Yaoundé, Cameroon CH Mbakam, MCO Assoumou, GB Jacobs, FA Azebaze, M Mesembe, ... Health Sciences and Disease 21 (2), 2020 | 1 | 2020 |
Small-molecule inhibitors of proteasome increase CjCas9 protein stability P Yaméogo, N Majeau, CH Mbakam, JP Tremblay PloS one 18 (1), e0280353, 2023 | | 2023 |
Développement d'une approche de thérapie génique de la dystrophie musculaire de Duchenne en utilisant la technologie CRISPR-Cas9 Prime editing CH Mbakam Université Laval, 2023 | | 2023 |
Développement d'une approche de thérapie génique de la dystrophie musculaire de Duchenne en utilisant la technologie CRISPR-Cas9 Prime editing C Happi Mbakam | | 2023 |
FP. 42 Correction of point mutations in the DMD gene using the prime editing CH Mbakam, J Rousseau, J Tremblay Neuromuscular Disorders 32, S125, 2022 | | 2022 |
Insertion of the Icelandic mutation (A673T) in the APP gene using the CRISPR/Cas9 base editing and Prime editing technologies, a preventive treatment for … JP Tremblay, G Tremblay, A Guyon, R Joël, C Happi‐Mbakam Alzheimer's & Dementia 17, e058710, 2021 | | 2021 |
DMD–ANIMAL MODELS: EP. 94 Efficient modification of DMD gene using PRIME editing CH Mbakam, J Rousseau, G Tremblay, J Tremblay Neuromuscular Disorders 31, S77-S78, 2021 | | 2021 |
Kinetics of CD4+ T-cell recovery amongst HIV load suppressed patients on first-line antiretroviral therapy in Yaoundé, Cameroon CH Mbakam, JM Nwobegahay, CF Mezajou, FA Azebaze, LM Nguimbus, ... International Journal of Biological and Chemical Sciences 15 (3), 881-888, 2021 | | 2021 |
Comparison of Prime Editing and Base Editing for the Insertion of a Mutation in the APP Gene G Tremblay, J Rousseau, C Happi-Mbakam, A Guyon, JP Tremblay MOLECULAR THERAPY 29 (4), 207-207, 2021 | | 2021 |