| Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation T Garzon-Muvdi, P Schiapparelli, C ap Rhys, H Guerrero-Cazares, ... PLoS biology 10 (5), e1001320, 2012 | 170 | 2012 |
| Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis O Kilic, D Pamies, E Lavell, P Schiapparelli, Y Feng, T Hartung, ... Lab on a Chip 16 (21), 4152-4162, 2016 | 151 | 2016 |
| Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival. A Mangraviti, SY Tzeng, D Gullotti, KL Kozielski, JE Kim, M Seng, ... Biomaterials, 2016 | 97 | 2016 |
| Characterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization. IM Yang JM, Schiapparelli P, Nguyen HN, Igarashi A, Zhang Q, Abbadi S, Amzel ... Oncogene, 2017 | 89* | 2017 |
| Cancer-selective nanoparticles for combinatorial siRNA delivery to primary human GBM in vitro and in vivo KL Kozielski, A Ruiz-Valls, SY Tzeng, H Guerrero-Cázares, Y Rui, Y Li, ... Biomaterials 209, 79-87, 2019 | 77 | 2019 |
| Migration Phenotype of Brain-Cancer Cells Predicts Patient Outcomes CL Smith, O Kilic, P Schiapparelli, H Guerrero-Cazares, DH Kim, ... Cell reports 15 (12), 2616-2624, 2016 | 77 | 2016 |
| Brachyury-YAP regulatory axis drives stemness and growth in cancer SR Shah, JM David, ND Tippens, A Mohyeldin, JC Martinez-Gutierrez, ... Cell reports 21 (2), 495-507, 2017 | 76 | 2017 |
| NKCC1 regulates migration ability of glioblastoma cells by modulation of actin dynamics and interacting with cofilin P Schiapparelli, H Guerrero-Cazares, R Magaña-Maldonado, SM Hamilla, ... EBioMedicine 21, 94-103, 2017 | 72 | 2017 |
| A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine. PD Plummer S, Wallace S, Ball G, Lloyd R, Schiapparelli P, Quiñones-Hinojosa ... Sci Rep, 2019 | 69 | 2019 |
| Nanotherapeutic systems for local treatment of brain tumors RW Chakroun, P Zhang, R Lin, P Schiapparelli, A Quinones‐Hinojosa, ... Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 10 (1 …, 2018 | 69 | 2018 |
| Supramolecular Crafting of Self-Assembling Camptothecin Prodrugs with Enhanced Efficacy against Primary Cancer Cells H Su, P Zhang, AG Cheetham, JM Koo, R Lin, A Masood, P Schiapparelli, ... | 69 | 2016 |
| Self-assembling and self-formulating prodrug hydrogelator extends survival in a glioblastoma resection and recurrence model P Schiapparelli, P Zhang, M Lara-Velazquez, H Guerrero-Cazares, R Lin, ... Journal of Controlled Release 319, 311-321, 2020 | 57 | 2020 |
| Cellular microenvironment modulates the galvanotaxis of brain tumor initiating cells YJ Huang, G Hoffmann, B Wheeler, P Schiapparelli, A Quinones-Hinojosa, ... Scientific reports 6 (1), 1-10, 2016 | 55 | 2016 |
| Engineering three-dimensional tumor models to study glioma cancer stem cells and tumor microenvironment H Ruiz-Garcia, K Alvarado-Estrada, P Schiapparelli, ... Frontiers in Cellular Neuroscience 14, 558381, 2020 | 49 | 2020 |
| A microfluidic cell-migration assay for the prediction of progression-free survival and recurrence time of patients with glioblastoma BS Wong, SR Shah, CL Yankaskas, VK Bajpai, PH Wu, D Chin, ... Nature biomedical engineering 5 (1), 26-40, 2021 | 43 | 2021 |
| Verteporfin-Loaded Polymeric Microparticles for Intratumoral Treatment of Brain Cancer SR Shah, J Kim, P Schiapparelli, CA Vazquez-Ramos, ... Molecular pharmaceutics 16 (4), 1433-1443, 2019 | 40 | 2019 |
| Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells P Schiapparelli, MH Shahi, M Enguita-Germán, JI Johnsen, P Kogner, ... Cancer letters 310 (2), 222-231, 2011 | 38 | 2011 |
| Expression and epigenetic modulation of sonic hedgehog-GLI1 pathway genes in neuroblastoma cell lines and tumors MH Shahi, P Schiapparelli, M Afzal, S Sinha, JA Rey, JS Castresana Tumor Biology 32 (1), 113-127, 2011 | 35 | 2011 |
| CD133+ cells from medulloblastoma and PNET cell lines are more resistant to cyclopamine inhibition of the sonic hedgehog signaling pathway than CD133− cells M Enguita-Germán, P Schiapparelli, JA Rey, JS Castresana Tumor Biology 31 (5), 381-390, 2010 | 27 | 2010 |
| Regulation of Glioblastoma Tumor-Propagating Cells by the Integrin Partner Tetraspanin CD151 J Tilghman, P Schiapparelli, B Lal, M Ying, A Quinones-Hinojosa, S Xia, ... Neoplasia 18 (3), 185-198, 2016 | 25 | 2016 |
Alfredo Quinones-Hinojosa Professor of Neurological Surgery and Oncology Neuroscience and Cellular and Molecular MedicineVerified email at jhmi.edu
