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David DeGraff
David DeGraff
Pennsylvania State University College of Medicine
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Year
Intratumoral heterogeneity of bladder cancer by molecular subtypes and histologic variants
JI Warrick, G Sjödahl, M Kaag, JD Raman, S Merrill, L Shuman, G Chen, ...
European urology 75 (1), 18-22, 2019
2022019
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer
SV Lindskrog, F Prip, P Lamy, A Taber, CS Groeneveld, ...
Nature communications 12 (1), 2301, 2021
1762021
Wnt/β-catenin activation promotes prostate tumor progression in a mouse model
X Yu, Y Wang, DJ DeGraff, ML Wills, RJ Matusik
Oncogene 30 (16), 1868-1879, 2011
1452011
FOXA1, GATA3 and PPARɣ cooperate to drive luminal subtype in bladder cancer: a molecular analysis of established human cell lines
JI Warrick, V Walter, H Yamashita, E Chung, L Shuman, VO Amponsa, ...
Scientific reports 6 (1), 38531, 2016
1432016
Mouse models of prostate cancer: picking the best model for the question
MM Grabowska, DJ DeGraff, X Yu, RJ Jin, Z Chen, AD Borowsky, ...
Cancer and Metastasis Reviews 33, 377-397, 2014
1212014
Genomic heterogeneity in bladder cancer: challenges and possible solutions to improve outcomes
JJ Meeks, H Al-Ahmadie, BM Faltas, JA Taylor III, TW Flaig, DJ DeGraff, ...
Nature Reviews Urology 17 (5), 259-270, 2020
1132020
Loss of the urothelial differentiation marker FOXA1 is associated with high grade, late stage bladder cancer and increased tumor proliferation
DJ DeGraff, PE Clark, JM Cates, H Yamashita, VL Robinson, X Yu, ...
PloS one 7 (5), e36669, 2012
1122012
Activation of NF-kappa B signaling promotes growth of prostate cancer cells in bone
R Jin, JA Sterling, JR Edwards, DJ DeGraff, C Lee, SI Park, RJ Matusik
PloS one 8 (4), e60983, 2013
1032013
NFI transcription factors interact with FOXA1 to regulate prostate-specific gene expression
MM Grabowska, AD Elliott, DJ DeGraff, PD Anderson, G Anumanthan, ...
Molecular endocrinology 28 (6), 949-964, 2014
772014
Macrophage migratory inhibitory factor promotes bladder cancer progression via increasing proliferation and angiogenesis
S Choudhary, P Hegde, JR Pruitt, TM Sielecki, D Choudhary, K Scarpato, ...
Carcinogenesis 34 (12), 2891-2899, 2013
712013
Loss of FOXA1 drives sexually dimorphic changes in urothelial differentiation and is an independent predictor of poor prognosis in bladder cancer
OL Reddy, JM Cates, LL Gellert, HS Crist, Z Yang, H Yamashita, ...
The American journal of pathology 185 (5), 1385-1395, 2015
702015
Tailoring peptidomimetics for targeting protein–protein interactions
ON Akram, DJ DeGraff, JH Sheehan, WD Tilley, RJ Matusik, JM Ahn, ...
Molecular Cancer Research 12 (7), 967-978, 2014
612014
SOX2 expression in the developing, adult, as well as, diseased prostate
X Yu, JM Cates, C Morrissey, C You, MM Grabowska, J Zhang, ...
Prostate cancer and prostatic diseases 17 (4), 301-309, 2014
532014
Disease evidence for IGFBP-2 as a key player in prostate cancer progression and development of osteosclerotic lesions
DJ DeGraff, AA Aguiar, RA Sikes
American Journal of Translational Research 1 (2), 115, 2009
532009
When urothelial differentiation pathways go wrong: implications for bladder cancer development and progression
DJ DeGraff, JM Cates, JR Mauney, PE Clark, RJ Matusik, RM Adam
Urologic Oncology: Seminars and Original Investigations 31 (6), 802-811, 2013
512013
FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype
DJ DeGraff, MM Grabowska, TC Case, X Yu, MK Herrick, WJ Hayward, ...
Laboratory investigation 94 (7), 726-739, 2014
492014
Evaluation of PD-L1 and other immune markers in bladder urothelial carcinoma stratified by histologic variants and molecular subtypes
H Li, Q Zhang, L Shuman, M Kaag, JD Raman, S Merrill, DJ DeGraff, ...
Scientific reports 10 (1), 1439, 2020
462020
Suppression of p16 induces mTORC1-mediated nucleotide metabolic reprogramming
R Buj, CW Chen, ES Dahl, KE Leon, R Kuskovsky, N Maglakelidze, ...
Cell reports 28 (8), 1971-1980. e8, 2019
442019
FOXA1 and CK14 as markers of luminal and basal subtypes in histologic variants of bladder cancer and their associated conventional urothelial carcinoma
JI Warrick, M Kaag, JD Raman, W Chan, T Tran, S Kunchala, L Shuman, ...
Virchows Archiv 471, 337-345, 2017
442017
Mutational profile of endometrial hyperplasia and risk of progression to endometrioid adenocarcinoma
M Russo, JM Newell, L Budurlean, KR Houser, K Sheldon, J Kesterson, ...
Cancer 126 (12), 2775-2783, 2020
412020
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