Evolved Cas9 variants with broad PAM compatibility and high DNA specificity JH Hu, SM Miller, MH Geurts, W Tang, L Chen, N Sun, CM Zeina, X Gao, ... Nature 556 (7699), 57-63, 2018 | 1498 | 2018 |
Salicylaldehyde azines as fluorophores of aggregation-induced emission enhancement characteristics W Tang, Y Xiang, A Tong The Journal of organic chemistry 74 (5), 2163-2166, 2009 | 293 | 2009 |
Rewritable multi-event analog recording in bacterial and mammalian cells W Tang, DR Liu Science 360 (6385), eaap8992, 2018 | 245 | 2018 |
Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation W Tang, JH Hu, DR Liu Nature communications 8 (1), 15939, 2017 | 216 | 2017 |
Lantibiotics from Geobacillus thermodenitrificans N Garg, W Tang, Y Goto, SK Nair, WA Van Der Donk Proceedings of the National Academy of Sciences 109 (14), 5241-5246, 2012 | 150 | 2012 |
The sequence of the enterococcal cytolysin imparts unusual lanthionine stereochemistry W Tang, WA Van Der Donk Nature chemical biology 9 (3), 157-159, 2013 | 109 | 2013 |
Structural characterization of four prochlorosins: a novel class of lantipeptides produced by planktonic marine cyanobacteria W Tang, WA Van Der Donk Biochemistry 51 (21), 4271-4279, 2012 | 103 | 2012 |
Substrate control in stereoselective lanthionine biosynthesis W Tang, G Jiménez-Osés, KN Houk, WA Van Der Donk Nature chemistry 7 (1), 57-64, 2015 | 89 | 2015 |
The enterococcal cytolysin synthetase has an unanticipated lipid kinase fold SH Dong, W Tang, T Lukk, Y Yu, SK Nair, WA van der Donk Elife 4, e07607, 2015 | 82 | 2015 |
Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS Q Zhang, M Ortega, Y Shi, H Wang, JO Melby, W Tang, DA Mitchell, ... Proceedings of the National Academy of Sciences 111 (33), 12031-12036, 2014 | 63 | 2014 |
Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination YL Xiao, S Liu, R Ge, Y Wu, C He, M Chen, W Tang Nature biotechnology 41 (7), 993-1003, 2023 | 54 | 2023 |
Fluorescent salicylaldehyde hydrazone as selective chemosensor for Zn2+ in aqueous ethanol: a ratiometric approach N Li, W Tang, Y Xiang, A Tong, P Jin, Y Ju Luminescence 25 (6), 445-451, 2010 | 39 | 2010 |
Enrichment of the β-catenin–TCF complex at the S and G2 phases ensures cell survival and cell cycle progression Y Ding, S Su, W Tang, X Zhang, S Chen, G Zhu, J Liang, W Wei, Y Guo, ... Journal of cell science 127 (22), 4833-4845, 2014 | 34 | 2014 |
Structural determinants of macrocyclization in substrate-controlled lanthipeptide biosynthetic pathways SC Bobeica, L Zhu, JZ Acedo, W Tang, WA Van Der Donk Chemical Science 11 (47), 12854-12870, 2020 | 27 | 2020 |
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation W Tang, JH Hu, DR Liu US Patent 11,560,566, 2023 | 26 | 2023 |
Applications of the class II lanthipeptide protease LicP for sequence-specific, traceless peptide bond cleavage W Tang, SH Dong, LM Repka, C He, SK Nair, WA Van Der Donk Chemical Science 6 (11), 6270-6279, 2015 | 22 | 2015 |
The enterococcal cytolysin synthetase coevolves with substrate for stereoselective lanthionine synthesis W Tang, GN Thibodeaux, WA Van Der Donk ACS chemical biology 11 (9), 2438-2446, 2016 | 17 | 2016 |
CylA is a sequence-specific protease involved in toxin biosynthesis W Tang, SC Bobeica, L Wang, WA van der Donk Journal of Industrial Microbiology and Biotechnology 46 (3-4), 537-549, 2019 | 12 | 2019 |
An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity T Wu, C Liu, S Zou, R Lyu, B Yang, H Yan, M Zhao, W Tang Nature chemical biology 19 (11), 1384-1393, 2023 | 8 | 2023 |
Structure–Activity Relationships of the Enterococcal Cytolysin IR Rahman, A Sanchez, W Tang, WA Van Der Donk ACS infectious diseases 7 (8), 2445-2454, 2021 | 8 | 2021 |