| Lifespan extension by reduction of the growth hormone‐insulin‐like growth factor‐1 axis: relation to caloric restriction I Shimokawa, Y Higami, T Tsuchiya, H Otani, T Komatsu, T Chiba, ... The FASEB Journal 17 (9), 1108-1109, 2003 | 155 | 2003 |
| Identification of peak bone mass QTL in a spontaneously osteoporotic mouse strain M Shimizu, K Higuchi, B Bennett, C Xia, T Tsuboyama, S Kasai, T Chiba, ... Mammalian Genome 10, 81-87, 1999 | 129 | 1999 |
| Transmission of mouse senile amyloidosis Y Xing, A Nakamura, T Chiba, K Kogishi, T Matsushita, F Li, Z Guo, ... Laboratory investigation 81 (4), 493-499, 2001 | 125 | 2001 |
| Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model I Shimokawa, Y Higami, M Utsuyama, T Tuchiya, T Komatsu, T Chiba, ... The American journal of pathology 160 (6), 2259-2265, 2002 | 120 | 2002 |
| SV40 T antigen interacts with Nbs1 to disrupt DNA replication control X Wu, D Avni, T Chiba, F Yan, Q Zhao, Y Lin, H Heng, D Livingston Genes & development 18 (11), 1305-1316, 2004 | 113 | 2004 |
| FoxO1 is involved in the antineoplastic effect of calorie restriction H Yamaza, T Komatsu, S Wakita, C Kijogi, S Park, H Hayashi, T Chiba, ... Aging cell 9 (3), 372-382, 2010 | 111 | 2010 |
| The life‐extending effect of dietary restriction requires F oxo3 in mice I Shimokawa, T Komatsu, N Hayashi, SE Kim, T Kawata, S Park, ... Aging cell 14 (4), 707-709, 2015 | 104 | 2015 |
| DNA polymerase θ (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse Z Wang, Y Song, S Li, S Kurian, R Xiang, T Chiba, X Wu Journal of Biological Chemistry 294 (11), 3909-3919, 2019 | 93 | 2019 |
| The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted E Liu, AYL Lee, T Chiba, E Olson, P Sun, X Wu The Journal of cell biology 179 (4), 643-657, 2007 | 88 | 2007 |
| Manipulation of caloric content but not diet composition, attenuates the deficit in learning and memory of senescence-accelerated mouse strain P8 T Komatsu, T Chiba, H Yamaza, K Yamashita, A Shimada, Y Hoshiyama, ... Experimental gerontology 43 (4), 339-346, 2008 | 74 | 2008 |
| Anti‐aging effects of caloric restriction: Involvement of neuroendocrine adaptation by peripheral signaling T Chiba, H Yamaza, Y Higami, I Shimokawa Microscopy research and technique 59 (4), 317-324, 2002 | 61 | 2002 |
| Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint AYL Lee, T Chiba, LN Truong, AN Cheng, J Do, MJ Cho, L Chen, X Wu Journal of Biological Chemistry 287 (4), 2531-2543, 2012 | 60 | 2012 |
| PIF1 helicase promotes break‐induced replication in mammalian cells S Li, H Wang, S Jehi, J Li, S Liu, Z Wang, L Truong, T Chiba, Z Wang, ... The EMBO Journal 40 (8), e104509, 2021 | 59 | 2021 |
| Fibrilization in mouse senile amyloidosis is fibril conformation-dependent. K Higuchi, K Kogishi, J Wang, X Chen, T Chiba, T Matsushita, Y Hoshii, ... Laboratory investigation; a journal of technical methods and pathology 78 …, 1998 | 58 | 1998 |
| Release of TNF‐α from macrophages is mediated by small GTPase Rab37 R Mori, K Ikematsu, T Kitaguchi, SE Kim, M Okamoto, T Chiba, A Miyawaki, ... European journal of immunology 41 (11), 3230-3239, 2011 | 53 | 2011 |
| Down-regulation of AMP-activated protein kinase by calorie restriction in rat liver K To, H Yamaza, T Komatsu, T Hayashida, H Hayashi, H Toyama, ... Experimental gerontology 42 (11), 1063-1071, 2007 | 53 | 2007 |
| Hand grip strength as a predictor of postoperative complications in esophageal cancer patients undergoing esophagectomy S Sato, E Nagai, Y Taki, M Watanabe, Y Watanabe, K Nakano, H Yamada, ... Esophagus 15, 10-18, 2018 | 52 | 2018 |
| SIRT1 regulates thyroid-stimulating hormone release by enhancing PIP5Kγ activity through deacetylation of specific lysine residues in mammals S Akieda-Asai, N Zaima, K Ikegami, T Kahyo, I Yao, T Hatanaka, S Iemura, ... PloS one 5 (7), e11755, 2010 | 51 | 2010 |
| Longevity genes: insights from calorie restriction and genetic longevity models I Shimokawa, T Chiba, H Yamaza, T Komatsu Molecules and cells 26 (5), 427-435, 2008 | 51 | 2008 |
| A key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction T Chiba, Y Tamashiro, D Park, T Kusudo, R Fujie, T Komatsu, SE Kim, ... Scientific reports 4 (1), 4517, 2014 | 47 | 2014 |
