Rotaxanes as new architectures for photoinduced electron transfer and molecular motions MJ Blanco, MC Jimenez, JC Chambron, V Heitz, M Linke, JP Sauvage Chemical Society Reviews 28 (5), 293-305, 1999 | 381 | 1999 |
Impact of cross-coupling reactions in drug discovery and development MJ Buskes, MJ Blanco Molecules 25 (15), 3493, 2020 | 169 | 2020 |
Cyclic peptide natural products chart the frontier of oral bioavailability in the pursuit of undruggable targets MR Naylor, AT Bockus, MJ Blanco, RS Lokey Current Opinion in Chemical Biology 38, 141-147, 2017 | 145 | 2017 |
How hydrogen bonds impact P-glycoprotein transport and permeability PV Desai, TJ Raub, MJ Blanco Bioorganic & medicinal chemistry letters 22 (21), 6540-6548, 2012 | 133 | 2012 |
Lipophilic permeability efficiency reconciles the opposing roles of lipophilicity in membrane permeability and aqueous solubility MR Naylor, AM Ly, MJ Handford, DP Ramos, CR Pye, A Furukawa, ... Journal of medicinal chemistry 61 (24), 11169-11182, 2018 | 130 | 2018 |
Target engagement in lead generation TB Durham, MJ Blanco Bioorganic & medicinal chemistry letters 25 (5), 998-1008, 2015 | 102 | 2015 |
New chemical modalities and strategic thinking in early drug discovery MJ Blanco, KM Gardinier ACS medicinal chemistry letters 11 (3), 228-231, 2020 | 84 | 2020 |
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1′-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid … G Martinez Botella, FG Salituro, BL Harrison, RT Beresis, Z Bai, ... Journal of Medicinal Chemistry 60 (18), 7810-7819, 2017 | 84 | 2017 |
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1′-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid … G Martinez Botella, FG Salituro, BL Harrison, RT Beresis, Z Bai, ... Journal of Medicinal Chemistry 60 (18), 7810-7819, 2017 | 84 | 2017 |
Stereochemistry balances cell permeability and solubility in the naturally derived phepropeptin cyclic peptides J Schwochert, Y Lao, CR Pye, MR Naylor, PV Desai, ... ACS Medicinal Chemistry Letters 7 (8), 757-761, 2016 | 61 | 2016 |
TRP channels as emerging targets for pain therapeutics LM Broad, AJ Mogg, RE Beattie, AM Ogden, MJ Blanco, D Bleakman Expert opinion on therapeutic targets 13 (1), 69-81, 2009 | 61 | 2009 |
Enantiospecific and stereoselective synthesis of polyhydroxylated pyrrolidines and indolizidines from trans-4-hydroxy-L-proline MJ Blanco, FJ Sardina The Journal of organic chemistry 61 (14), 4748-4755, 1996 | 60 | 1996 |
Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive … GB Martinez, FG Salituro, BL Harrison, RT Beresis, Z Bai, MJ Blanco, ... Journal of medicinal chemistry 60 (18), 7810-7819, 2017 | 58 | 2017 |
Recent progress in the development of selective TRPV1 antagonists for pain LM Broad, SJ Keding, MJ Blanco Current topics in medicinal chemistry 8 (16), 1431-1441, 2008 | 49 | 2008 |
Transition‐Metal‐Templated Synthesis of Rotaxanes MJ Blanco, JC Chambron, MC Jiménez, JP Sauvage Topics in Stereochemistry 23, 125-173, 2002 | 48 | 2002 |
Diaryl ethers as opioid receptor antagonist MJ Blanco-Pillado, MG De La Torre, ND Buezo, WG Holloway, JE Matt, ... US Patent 7,381,719, 2008 | 47* | 2008 |
A linear multiporphyrinic [2]-rotaxane via amide bond formation MJ Blanco, JC Chambron, V Heitz, JP Sauvage Organic Letters 2 (20), 3051-3054, 2000 | 46 | 2000 |
C-3-and C-4-alkylated polyhydroxypyrrolidines: Enantiospecific syntheses and glycosidase inhibitory activity MJ Blanco, FJ Sardina The Journal of Organic Chemistry 63 (10), 3411-3416, 1998 | 46 | 1998 |
Breakthroughs in neuroactive steroid drug discovery MJ Blanco, D La, Q Coughlin, CA Newman, AM Griffin, BL Harrison, ... Bioorganic & medicinal chemistry letters 28 (2), 61-70, 2018 | 38 | 2018 |
Impact of allosteric modulation in drug discovery: innovation in emerging chemical modalities B Han, FG Salituro, MJ Blanco ACS Medicinal Chemistry Letters 11 (10), 1810-1819, 2020 | 34 | 2020 |