| The perivascular niche regulates breast tumour dormancy CM Ghajar, H Peinado, H Mori, IR Matei, KJ Evason, H Brazier, D Almeida, ... Nature cell biology 15 (7), 807-817, 2013 | 1116 | 2013 |
| Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2 CA Doege, K Inoue, T Yamashita, DB Rhee, S Travis, R Fujita, ... Nature 488 (7413), 652-655, 2012 | 408 | 2012 |
| Adaptation of energy metabolism in breast cancer brain metastases EI Chen, J Hewel, JS Krueger, C Tiraby, MR Weber, A Kralli, K Becker, ... Cancer research 67 (4), 1472-1486, 2007 | 375 | 2007 |
| Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system SM Buckley, B Aranda-Orgilles, A Strikoudis, E Apostolou, E Loizou, ... Cell stem cell 11 (6), 783-798, 2012 | 288 | 2012 |
| Optimization of mass spectrometry-compatible surfactants for shotgun proteomics EI Chen, D Cociorva, JL Norris, JR Yates Journal of proteome research 6 (7), 2529-2538, 2007 | 275 | 2007 |
| Substrate hydrolysis by matrix metalloproteinase-9 SJ Kridel, E Chen, LP Kotra, EW Howard, S Mobashery, JW Smith Journal of Biological Chemistry 276 (23), 20572-20578, 2001 | 261 | 2001 |
| Large scale protein profiling by combination of protein fractionation and multidimensional protein identification technology (MudPIT) EI Chen, J Hewel, B Felding-Habermann, JR Yates III Molecular & Cellular Proteomics 5 (1), 53-56, 2006 | 216 | 2006 |
| Identification of a stem-like cell population by exposing metastatic breast cancer cell lines to repetitive cycles of hypoxia and reoxygenation E Louie, S Nik, J Chen, M Schmidt, B Song, C Pacson, XF Chen, S Park, ... Breast Cancer Research 12 (6), 1-14, 2010 | 189 | 2010 |
| Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway K Inoue, J Rispoli, H Kaphzan, E Klann, EI Chen, J Kim, M Komatsu, ... Molecular neurodegeneration 7 (1), 1-13, 2012 | 174 | 2012 |
| A unique substrate recognition profile for matrix metalloproteinase-2 EI Chen, SJ Kridel, EW Howard, W Li, A Godzik, JW Smith Journal of Biological Chemistry 277 (6), 4485-4491, 2002 | 161 | 2002 |
| Keratin 17 in premalignant and malignant squamous lesions of the cervix: proteomic discovery and immunohistochemical validation as a diagnostic and prognostic biomarker LF Escobar-Hoyos, J Yang, J Zhu, JA Cavallo, H Zhai, S Burke, A Koller, ... Modern Pathology 27 (4), 621-630, 2014 | 155 | 2014 |
| PatternLab for proteomics: a tool for differential shotgun proteomics PC Carvalho, JSG Fischer, EI Chen, JR Yates, VC Barbosa BMC bioinformatics 9 (1), 1-14, 2008 | 150 | 2008 |
| Proteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-RKT, a major regulator of cell surface … NM Andronicos, EI Chen, N Baik, H Bai, CM Parmer, WB Kiosses, ... Blood, The Journal of the American Society of Hematology 115 (7), 1319-1330, 2010 | 148 | 2010 |
| FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification N Kourtis, RS Moubarak, B Aranda-Orgilles, K Lui, IT Aydin, T Trimarchi, ... Nature cell biology 17 (3), 322-332, 2015 | 145 | 2015 |
| MicroRNA-195 regulates metabolism in failing myocardium via alterations in sirtuin 3 expression and mitochondrial protein acetylation X Zhang, R Ji, X Liao, E Castillero, PJ Kennel, DL Brunjes, M Franz, ... Circulation 137 (19), 2052-2067, 2018 | 137 | 2018 |
| Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo A Beliveau, JD Mott, A Lo, EI Chen, AA Koller, P Yaswen, J Muschler, ... Genes & development 24 (24), 2800-2811, 2010 | 125 | 2010 |
| A unique substrate binding mode discriminates membrane type-1 matrix metalloproteinase from other matrix metalloproteinases SJ Kridel, H Sawai, BI Ratnikov, EI Chen, W Li, A Godzik, AY Strongin, ... Journal of Biological Chemistry 277 (26), 23788-23793, 2002 | 125 | 2002 |
| Cancer proteomics by quantitative shotgun proteomics EI Chen, JR Yates III Molecular oncology 1 (2), 144-159, 2007 | 116 | 2007 |
| Neurotrophin-3 modulates breast cancer cells and the microenvironment to promote the growth of breast cancer brain metastasis E Louie, XF Chen, A Coomes, K Ji, S Tsirka, EI Chen Oncogene 32 (35), 4064-4077, 2013 | 115 | 2013 |
| Lambda interferon restructures the nasal microbiome and increases susceptibility to Staphylococcus aureus superinfection PJ Planet, D Parker, TS Cohen, H Smith, JD Leon, C Ryan, TJ Hammer, ... MBio 7 (1), 2016 | 109 | 2016 |
