A biomarker that identifies senescent human cells in culture and in aging skin in vivo. GP Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, EE Medrano, ... Proceedings of the National Academy of Sciences 92 (20), 9363-9367, 1995 | 8622 | 1995 |
Cellular senescence: when bad things happen to good cells J Campisi, F d'Adda di Fagagna Nature reviews Molecular cell biology 8 (9), 729-740, 2007 | 5001 | 2007 |
The senescence-associated secretory phenotype: the dark side of tumor suppression JP Coppé, PY Desprez, A Krtolica, J Campisi Annual review of pathology: mechanisms of disease 5 (1), 99-118, 2010 | 4705 | 2010 |
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor JP Coppé, CK Patil, F Rodier, YU Sun, DP Muñoz, J Goldstein, PS Nelson, ... PLoS biology 6 (12), e301, 2008 | 4080 | 2008 |
Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases C Franceschi, J Campisi Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2014 | 3703 | 2014 |
Chronic inflammation in the etiology of disease across the life span D Furman, J Campisi, E Verdin, P Carrera-Bastos, S Targ, C Franceschi, ... Nature medicine 25 (12), 1822-1832, 2019 | 3224 | 2019 |
Aging, cellular senescence, and cancer J Campisi Annual review of physiology 75 (1), 685-705, 2013 | 2975 | 2013 |
Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors J Campisi Cell 120 (4), 513-522, 2005 | 2788 | 2005 |
Four faces of cellular senescence F Rodier, J Campisi Journal of Cell Biology 192 (4), 547-556, 2011 | 2344 | 2011 |
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion F Rodier, JP Coppé, CK Patil, WAM Hoeijmakers, DP Muñoz, SR Raza, ... Nature cell biology 11 (8), 973-979, 2009 | 2295 | 2009 |
Geroscience: linking aging to chronic disease BK Kennedy, SL Berger, A Brunet, J Campisi, AM Cuervo, ES Epel, ... Cell 159 (4), 709-713, 2014 | 2123 | 2014 |
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging A Krtolica, S Parrinello, S Lockett, PY Desprez, J Campisi Proceedings of the National Academy of Sciences 98 (21), 12072-12077, 2001 | 1966 | 2001 |
Cellular senescence: defining a path forward V Gorgoulis, PD Adams, A Alimonti, DC Bennett, O Bischof, C Bishop, ... Cell 179 (4), 813-827, 2019 | 1960 | 2019 |
An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA M Demaria, N Ohtani, SA Youssef, F Rodier, W Toussaint, JR Mitchell, ... Developmental cell 31 (6), 722-733, 2014 | 1824 | 2014 |
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities T Tchkonia, Y Zhu, J Van Deursen, J Campisi, JL Kirkland The Journal of clinical investigation 123 (3), 966-972, 2013 | 1740 | 2013 |
Reversal of human cellular senescence: roles of the p53 and p16 pathways CM Beauséjour, A Krtolica, F Galimi, M Narita, SW Lowe, P Yaswen, ... The EMBO journal, 2003 | 1716 | 2003 |
Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo F Debacq-Chainiaux, JD Erusalimsky, J Campisi, O Toussaint Nature protocols 4 (12), 1798-1806, 2009 | 1684 | 2009 |
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice J Chang, Y Wang, L Shao, RM Laberge, M Demaria, J Campisi, ... Nature medicine 22 (1), 78-83, 2016 | 1663 | 2016 |
Inflammatory networks during cellular senescence: causes and consequences A Freund, AV Orjalo, PY Desprez, J Campisi Trends in molecular medicine 16 (5), 238-246, 2010 | 1518 | 2010 |
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts S Parrinello, E Samper, A Krtolica, J Goldstein, S Melov, J Campisi Nature cell biology 5 (8), 741-747, 2003 | 1337 | 2003 |