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Marcus R Kelly
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CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities
K Han, SE Pierce, A Li, K Spees, GR Anderson, JA Seoane, YH Lo, ...
Nature 580 (7801), 136-141, 2020
2262020
The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery
M Toriyama, C Lee, SP Taylor, I Duran, DH Cohn, AL Bruel, JM Tabler, ...
Nature genetics 48 (6), 648-656, 2016
1432016
Drebrin restricts rotavirus entry by inhibiting dynamin-mediated endocytosis
B Li, S Ding, N Feng, N Mooney, YS Ooi, L Ren, J Diep, MR Kelly, ...
Proceedings of the National Academy of Sciences 114 (18), E3642-E3651, 2017
672017
Comparative proteomics reveals strain-specific β-TrCP degradation via rotavirus NSP1 hijacking a host Cullin-3-Rbx1 complex
S Ding, N Mooney, B Li, MR Kelly, N Feng, AV Loktev, A Sen, JT Patton, ...
PLoS pathogens 12 (10), e1005929, 2016
622016
A multi-scale map of cell structure fusing protein images and interactions
Y Qin, EL Huttlin, CF Winsnes, ML Gosztyla, L Wacheul, MR Kelly, ...
Nature 600 (7889), 536-542, 2021
522021
Interpretation of cancer mutations using a multiscale map of protein systems
F Zheng, MR Kelly, DJ Ramms, ML Heintschel, K Tao, B Tutuncuoglu, ...
Science 374 (6563), eabf3067, 2021
352021
Combined proteomic and genetic interaction mapping reveals new RAS effector pathways and susceptibilities
MR Kelly, K Kostyrko, K Han, NA Mooney, EE Jeng, K Spees, PT Dinh, ...
Cancer discovery 10 (12), 1950-1967, 2020
332020
Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth
R Tang, EG Shuldiner, M Kelly, CW Murray, JD Hebert, L Andrejka, ...
Nature cell biology 25 (1), 159-169, 2023
82023
A multi-scale map of protein assemblies in the DNA damage response
A Kratz, M Kim, MR Kelly, F Zheng, CA Koczor, J Li, K Ono, Y Qin, ...
Cell Systems 14 (6), 447-463. e8, 2023
72023
University of Washington Center for Mendelian Genomics The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery
M Toriyama, C Lee, SP Taylor, I Duran, DH Cohn, AL Bruel, JM Tabler, ...
Nat. Genet 48, 648-656, 2016
72016
Duffourd Y, Faivre L, Rivière JB, Chen J, Liu KJ, Marcotte EM, Hildebrandt F, Thauvin-Robinet C, Krakow D, Jackson PK, Wallingford JB. The ciliopathy-associated CPLANE proteins …
M Toriyama, C Lee, SP Taylor, I Duran, DH Cohn, AL Bruel, JM Tabler, ...
Nat Genet 48, 648-56, 2016
52016
UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma
K Kostyrko, M Román, AG Lee, DR Simpson, PT Dinh, SG Leung, ...
Nature communications 14 (1), 3966, 2023
32023
Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growth
R Tang, EG Shuldiner, M Kelly, CW Murray, JD Hebert, L Andrejka, ...
bioRxiv, 2021.07. 08.451571, 2021
22021
A deep learning model of tumor cell architecture elucidates response and resistance to CDK4/6 inhibitors
S Park, E Silva, A Singhal, MR Kelly, K Licon, I Panagiotou, C Fogg, ...
Nature Cancer, 1-14, 2024
12024
Abstract B25: Combined proteomic and genetic interaction mapping reveals new Ras pathway effectors and regulators
M Kelly, K Han, K Kostyrko, N Mooney, E Jeng, J Demeter, ...
Molecular Cancer Research 18 (5_Supplement), B25-B25, 2020
2020
Combinatorial knockout of Rap1GDS1 and RhoA leads to lethality in KRAS-driven non-small cell lung cancer.
K Kostyrko, M Kelly, K Han, E Jeng, D Morgens, M Bassik, P Jackson, ...
MOLECULAR CANCER RESEARCH 18 (5), 33-33, 2020
2020
Abstract PR07: Combinatorial knockout of Rap1GDS1 and RhoA leads to lethality in KRAS-driven non-small cell lung cancer
K Kostyrko, M Kelly, K Han, E Jeng, D Morgens, M Bassik, P Jackson, ...
Molecular Cancer Research 18 (5_Supplement), PR07-PR07, 2020
2020
Proteomic and Genomic Mapping of the RAS Pathway in Lung Adenocarcinoma
MR Kelly
Stanford University, 2020
2020
A Physical and Genetic Interaction Map of the Ras Pathway in Lung Adenocarcinoma
MR Kelly
Stanford University, 2020
2020
Proteomic and genetic interaction mapping of the Ras pathway reveals new effectors and vulnerabilities
MR Kelly, K Han, K Kostyrko, EE Jeng, N Mooney, A Sweet-Cordero, ...
Cancer Research 79 (13_Supplement), 959-959, 2019
2019
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