| Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex JM Brittain, DB Duarte, SM Wilson, W Zhu, C Ballard, PL Johnson, N Liu, ... Nature medicine 17 (7), 822-829, 2011 | 240 | 2011 |
| Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation R Zhao, Y Kakihara, A Gribun, J Huen, G Yang, M Khanna, M Costanzo, ... The Journal of cell biology 180 (3), 563-578, 2008 | 218 | 2008 |
| Discovery and characterization of small molecules that target the GTPase Ral C Yan, D Liu, L Li, MF Wempe, S Guin, M Khanna, J Meier, B Hoffman, ... Nature 515 (7527), 443-447, 2014 | 154 | 2014 |
| Unique structural and stabilizing roles for the individual pseudouridine residues in the 1920 region of Escherichia coli 23S rRNA M Meroueh, PJ Grohar, J Qiu, J SantaLucia Jr, SA Scaringe, CS Chow Nucleic acids research 28 (10), 2075-2083, 2000 | 123 | 2000 |
| Hierarchical CRMP2 posttranslational modifications control NaV1. 7 function ET Dustrude, A Moutal, X Yang, Y Wang, M Khanna, R Khanna Proceedings of the National Academy of Sciences 113 (52), E8443-E8452, 2016 | 111 | 2016 |
| Structural insights into TDP-43 and effects of post-translational modifications L François-Moutal, S Perez-Miller, DD Scott, VG Miranda, N Mollasalehi, ... Frontiers in molecular neuroscience 12, 301, 2019 | 104 | 2019 |
| Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases M Khanna, CH Chen, A Kimble-Hill, B Parajuli, S Perez-Miller, ... Journal of Biological Chemistry 286 (50), 43486-43494, 2011 | 89 | 2011 |
| A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2. 2 trafficking and reverses inflammatory and postoperative pain behaviors L François-Moutal, Y Wang, A Moutal, KE Cottier, OK Melemedjian, ... Pain 156 (7), 1247-1264, 2015 | 77 | 2015 |
| CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide A Moutal, X Yang, W Li, KB Gilbraith, S Luo, S Cai, L François-Moutal, ... Pain 158 (12), 2301-2319, 2017 | 75 | 2017 |
| Target-specific support vector machine scoring in structure-based virtual screening: computational validation, in vitro testing in kinases, and effects on lung cancer cell … L Li, M Khanna, I Jo, F Wang, NM Ashpole, A Hudmon, SO Meroueh Journal of chemical information and modeling 51 (4), 755-759, 2011 | 67 | 2011 |
| (S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation … A Moutal, LA Chew, X Yang, Y Wang, SK Yeon, E Telemi, S Meroueh, ... Pain 157 (7), 1448-1463, 2016 | 61 | 2016 |
| (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5 A Moutal, L François-Moutal, S Perez-Miller, K Cottier, LA Chew, SK Yeon, ... Molecular neurobiology 53, 1959-1976, 2016 | 60 | 2016 |
| Small-molecule inhibition of the uPAR· uPA interaction: Synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis T Mani, F Wang, WE Knabe, AL Sinn, M Khanna, I Jo, GE Sandusky, ... Bioorganic & medicinal chemistry 21 (7), 2145-2155, 2013 | 60 | 2013 |
| Blocking CRMP2 SUMOylation reverses neuropathic pain A Moutal, ET Dustrude, TM Largent-Milnes, TW Vanderah, M Khanna, ... Molecular psychiatry 23 (11), 2119-2121, 2018 | 56 | 2018 |
| Thermodynamics of RNA hairpins containing single internal mismatches M Meroueh, CS Chow Nucleic acids research 27 (4), 1118-1125, 1999 | 56 | 1999 |
| Targeting multiple conformations leads to small molecule inhibitors of the uPAR· uPA protein–protein interaction that block cancer cell invasion M Khanna, F Wang, I Jo, WE Knabe, SM Wilson, L Li, K Bum-Erdene, J Li, ... ACS chemical biology 6 (11), 1232-1243, 2011 | 54 | 2011 |
| Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury–associated peripheral sensory neuropathy via block of N-and T … SS Bellampalli, Y Ji, A Moutal, S Cai, EMK Wijeratne, MA Gandini, J Yu, ... Pain 160 (1), 117-135, 2019 | 53 | 2019 |
| Inhibition of the Ubc9 E2 SUMO-conjugating enzyme–CRMP2 interaction decreases NaV1. 7 currents and reverses experimental neuropathic pain L François-Moutal, ET Dustrude, Y Wang, T Brustovetsky, A Dorame, W Ju, ... Pain 159 (10), 2115-2127, 2018 | 53 | 2018 |
| Discovery of novel regulators of aldehyde dehydrogenase isoenzymes B Parajuli, AC Kimble-Hill, M Khanna, Y Ivanova, S Meroueh, TD Hurley Chemico-biological interactions 191 (1-3), 153-158, 2011 | 53 | 2011 |
| CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy … AD Piekarz, MR Due, M Khanna, B Wang, MS Ripsch, R Wang, ... Molecular pain 8, 1744-8069-8-54, 2012 | 52 | 2012 |
Aubin MoutalSaint Louis UniversityVerified email at health.slu.edu
