Self‐Assembled Amphotericin B Is Probably Surrounded by Ergosterol: Bimolecular Interactions as Evidenced by Solid‐State NMR and CD Spectra Y Kasai, N Matsumori, Y Umegawa, S Matsuoka, H Ueno, H Ikeuchi, ... Chemistry–A European Journal 14 (4), 1178-1185, 2008 | 56 | 2008 |
Head-to-tail interaction between amphotericin B and ergosterol occurs in hydrated phospholipid membrane Y Umegawa, Y Nakagawa, K Tahara, H Tsuchikawa, N Matsumori, ... Biochemistry 51 (1), 83-89, 2012 | 49 | 2012 |
Ergosterol increases the intermolecular distance of amphotericin B in the membrane-bound assembly as evidenced by solid-state NMR Y Umegawa, N Matsumori, T Oishi, M Murata Biochemistry 47 (51), 13463-13469, 2008 | 46 | 2008 |
Bioactive fluorinated derivative of amphotericin B N Matsumori, Y Umegawa, T Oishi, M Murata Bioorganic & medicinal chemistry letters 15 (15), 3565-3567, 2005 | 37 | 2005 |
Membrane interaction of amphotericin B as single-length assembly examined by solid state NMR for uniformly 13C-enriched agent S Matsuoka, H Ikeuchi, Y Umegawa, N Matsumori, M Murata Bioorganic & medicinal chemistry 14 (19), 6608-6614, 2006 | 32 | 2006 |
The structure of the bimolecular complex between amphotericin B and ergosterol in membranes is stabilized by face-to-face van der Waals interaction with their rigid cyclic cores Y Nakagawa, Y Umegawa, N Matsushita, T Yamamoto, H Tsuchikawa, ... Biochemistry 55 (24), 3392-3402, 2016 | 29 | 2016 |
The perpendicular orientation of amphotericin B methyl ester in hydrated lipid bilayers supports the barrel-stave model T Yamamoto, Y Umegawa, M Yamagami, T Suzuki, H Tsuchikawa, ... Biochemistry 58 (17), 2282-2291, 2019 | 27 | 2019 |
Amphotericin B covalent dimers with carbonyl-amino linkage: a new probe for investigating ion channel assemblies Y Umegawa, N Matsumori, T Oishi, M Murata Tetrahedron letters 48 (19), 3393-3396, 2007 | 27 | 2007 |
The amphotericin B–ergosterol complex spans a lipid bilayer as a single-length assembly T Yamamoto, Y Umegawa, H Tsuchikawa, S Hanashima, N Matsumori, ... Biochemistry 58 (51), 5188-5196, 2019 | 25 | 2019 |
Ion channel complex of antibiotics as viewed by NMR M Murata, Y Kasai, Y Umegawa, N Matsushita, H Tsuchikawa, ... Pure and Applied Chemistry 81 (6), 1123-1129, 2009 | 23 | 2009 |
Amphotericin B assembles into seven-molecule ion channels: An NMR and molecular dynamics study Y Umegawa, T Yamamoto, M Dixit, K Funahashi, S Seo, Y Nakagawa, ... Science Advances 8 (24), eabo2658, 2022 | 21 | 2022 |
Effect of sterol side chain on ion channel formation by amphotericin B in lipid bilayers Y Nakagawa, Y Umegawa, T Takano, H Tsuchikawa, N Matsumori, ... Biochemistry 53 (19), 3088-3094, 2014 | 21 | 2014 |
Axial hydrogen at C7 position and bumpy tetracyclic core markedly reduce sterol’s affinity to amphotericin B in membrane Y Nakagawa, Y Umegawa, K Nonomura, N Matsushita, T Takano, ... Biochemistry 54 (2), 303-312, 2015 | 20 | 2015 |
Cholesterol-induced conformational change in the sphingomyelin headgroup S Hanashima, K Murakami, M Yura, Y Yano, Y Umegawa, H Tsuchikawa, ... Biophysical Journal 117 (2), 307-318, 2019 | 16 | 2019 |
Role of polyol moiety of amphotericin B in ion channel formation and sterol selectivity in bilayer membrane T Yamamoto, Y Umegawa, H Tsuchikawa, N Matsumori, S Hanashima, ... Bioorganic & medicinal chemistry 23 (17), 5782-5788, 2015 | 15 | 2015 |
Evaluation of diacylphospholipids as boundary lipids for bacteriorhodopsin from structural and functional aspects S Kawatake, Y Umegawa, S Matsuoka, M Murata, M Sonoyama Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (9), 2106-2115, 2016 | 14 | 2016 |
Stereoselective synthesis of the head group of archaeal phospholipid PGP-Me to investigate bacteriorhodopsin–lipid interactions J Cui, S Kawatake, Y Umegawa, S Lethu, M Yamagami, S Matsuoka, ... Organic & Biomolecular Chemistry 13 (41), 10279-10284, 2015 | 11 | 2015 |
Diosgenin-induced physicochemical effects on phospholipid bilayers in comparison with cholesterol JC Ondevilla, S Hanashima, A Mukogawa, Y Umegawa, M Murata Bioorganic & Medicinal Chemistry Letters 36, 127816, 2021 | 9 | 2021 |
Average conformation of branched chain lipid PGP-Me that accounts for the thermal stability and high-salinity resistance of archaeal membranes M Yamagami, H Tsuchikawa, J Cui, Y Umegawa, Y Miyazaki, S Seo, ... Biochemistry 58 (37), 3869-3879, 2019 | 9 | 2019 |
13C‐TmDOTA as versatile thermometer compound for solid‐state NMR of hydrated lipid bilayer membranes Y Umegawa, Y Tanaka, M Nobuaki, M Murata Magnetic Resonance in Chemistry 54 (3), 227-233, 2016 | 8 | 2016 |