| Quaternary ammonium compounds: an antimicrobial mainstay and platform for innovation to address bacterial resistance MC Jennings, KPC Minbiole, WM Wuest ACS infectious diseases 1 (7), 288-303, 2015 | 586 | 2015 |
| Natural products as platforms to overcome antibiotic resistance SE Rossiter, MH Fletcher, WM Wuest Chemical reviews 117 (19), 12415-12474, 2017 | 507 | 2017 |
| A new class of synthetic retinoid antibiotics effective against bacterial persisters W Kim, W Zhu, GL Hendricks, D Van Tyne, AD Steele, CE Keohane, ... Nature 556 (7699), 103-107, 2018 | 347 | 2018 |
| Biofilm‐eradicating properties of quaternary ammonium amphiphiles: simple mimics of antimicrobial peptides MC Jennings, LE Ator, TJ Paniak, KPC Minbiole, WM Wuest ChemBioChem 15 (15), 2211-2215, 2014 | 162 | 2014 |
| Are quaternary ammonium compounds, the workhorse disinfectants, effective against severe acute respiratory syndrome-coronavirus-2? CL Schrank, KPC Minbiole, WM Wuest ACS infectious diseases 6 (7), 1553-1557, 2020 | 135 | 2020 |
| A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus W Kim, G Zou, TPA Hari, IK Wilt, W Zhu, N Galle, HA Faizi, GL Hendricks, ... Proceedings of the National Academy of Sciences 116 (33), 16529-16534, 2019 | 128 | 2019 |
| From antimicrobial activity to mechanism of resistance: the multifaceted role of simple quaternary ammonium compounds in bacterial eradication KPC Minbiole, MC Jennings, LE Ator, JW Black, MC Grenier, JE LaDow, ... Tetrahedron 72 (25), 3559-3566, 2016 | 108 | 2016 |
| The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2 AR Mahoney, MM Safaee, WM Wuest, AL Furst Iscience 24 (4), 2021 | 105 | 2021 |
| Evolution of multi-component anion relay chemistry (ARC): construction of architecturally complex natural and unnatural products AB Smith III, WM Wuest Chemical communications, 5883-5895, 2008 | 100 | 2008 |
| Bioorganic Investigation of Multicationic Antimicrobials to Combat QAC-Resistant Staphylococcus aureus MC Jennings, BA Buttaro, KPC Minbiole, WM Wuest ACS infectious diseases 1 (7), 304-309, 2015 | 94 | 2015 |
| Intramolecular hydroamination of aminoalkynes with silver-phenanthroline catalysts. JM Carney, PJ Donoghue, WM Wuest, O Wiest, P Helquist Organic letters 10 (17), 3903-3906, 2008 | 93 | 2008 |
| Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms P Le, E Kunold, R Macsics, K Rox, MC Jennings, I Ugur, M Reinecke, ... Nature chemistry 12 (2), 145-158, 2020 | 84 | 2020 |
| Targeting S. mutans biofilms: a perspective on preventing dental caries AM Scharnow, AE Solinski, WM Wuest MedChemComm 10 (7), 1057-1067, 2019 | 80 | 2019 |
| Three siderophores from one bacterial enzymatic assembly line WM Wuest, ES Sattely, CT Walsh Journal of the American Chemical Society 131 (14), 5056-5057, 2009 | 76 | 2009 |
| Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase CE Keohane, AD Steele, C Fetzer, J Khowsathit, D Van Tyne, L Moynié, ... Journal of the American Chemical Society 140 (5), 1774-1782, 2018 | 68 | 2018 |
| Building a better quaternary ammonium compound (QAC): branched tetracationic antiseptic amphiphiles ME Forman, MC Jennings, WM Wuest, KPC Minbiole ChemMedChem 11 (13), 1401-1405, 2016 | 62 | 2016 |
| More QACs, more questions: Recent advances in structure activity relationships and hurdles in understanding resistance mechanisms KR Morrison, RA Allen, KPC Minbiole, WM Wuest Tetrahedron letters 60 (37), 150935, 2019 | 60 | 2019 |
| The antimicrobial activity of mono-, bis-, tris-, and tetracationic amphiphiles derived from simple polyamine platforms TJ Paniak, MC Jennings, PC Shanahan, MD Joyce, CN Santiago, ... Bioorganic & Medicinal Chemistry Letters 24 (24), 5824-5828, 2014 | 58 | 2014 |
| Computational screening and selection of cyclic peptide hairpin mimetics by molecular simulation and kinetic network models AM Razavi, WM Wuest, VA Voelz Journal of chemical information and modeling 54 (5), 1425-1432, 2014 | 56 | 2014 |
| SylC catalyzes ureido-bond formation during biosynthesis of the proteasome inhibitor syringolin A HJ Imker, CT Walsh, WM Wuest Journal of the American Chemical Society 131 (51), 18263-18265, 2009 | 55 | 2009 |
Kevin MinbioleProfessor of Chemistry, Villanova UniversityVerified email at villanova.edu
