CA-170–a potent small-molecule PD-L1 inhibitor or not? B Musielak, J Kocik, L Skalniak, K Magiera-Mularz, D Sala, M Czub, ... Molecules 24 (15), 2804, 2019 | 124 | 2019 |
Di-bromo-based small-molecule inhibitors of the PD-1/PD-L1 immune checkpoint M Konieczny, B Musielak, J Kocik, L Skalniak, D Sala, M Czub, ... Journal of Medicinal Chemistry 63 (19), 11271-11285, 2020 | 55 | 2020 |
Terphenyl-based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein− Protein Interaction D Muszak, E Surmiak, J Plewka, K Magiera-Mularz, J Kocik, B Musielak, ... | 49 | 2021 |
Human and mouse PD-L1: similar molecular structure, but different druggability profiles K Magiera-Mularz, J Kocik, B Musielak, J Plewka, D Sala, M Machula, ... Iscience 24 (1), 2021 | 49 | 2021 |
Multicomponent peptide stapling as a diversity‐driven tool for the development of inhibitors of protein–protein interactions MG Ricardo, AM Ali, J Plewka, E Surmiak, B Labuzek, CG Neochoritis, ... Angewandte Chemie International Edition 59 (13), 5235-5241, 2020 | 38 | 2020 |
Design, synthesis, and biological evaluation of imidazopyridines as PD-1/PD-L1 antagonists R Butera, M Ważyńska, K Magiera-Mularz, J Plewka, B Musielak, ... ACS Medicinal Chemistry Letters 12 (5), 768-773, 2021 | 37 | 2021 |
TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition MD Roganowicz, S Komurlu, S Mukherjee, J Plewka, SL Alam, ... PLoS pathogens 13 (10), e1006686, 2017 | 26 | 2017 |
Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity A Czarna, J Plewka, L Kresik, A Matsuda, A Karim, C Robinson, ... Structure 30 (8), 1050-1054. e2, 2022 | 25 | 2022 |
PD-L1 inhibitors: different classes, activities, and mechanisms of action E Surmiak, K Magiera-Mularz, B Musielak, D Muszak, J Kocik-Krol, R Kitel, ... International Journal of Molecular Sciences 22 (21), 11797, 2021 | 22 | 2021 |
Competition NMR for detection of hit/lead inhibitors of protein–protein interactions B Musielak, W Janczyk, I Rodriguez, J Plewka, D Sala, K Magiera-Mularz, ... Molecules 25 (13), 3017, 2020 | 16 | 2020 |
Antibody adsorption in protein‐A affinity chromatography–in situ measurement of nanoscale structure by small‐angle X‐ray scattering J Plewka, GL Silva, R Tscheließnig, H Rennhofer, C Dias‐Cabral, ... Journal of separation science 41 (22), 4122-4132, 2018 | 14 | 2018 |
The pearl necklace model in protein A chromatography: Molecular mechanisms at the resin interface G L. Silva, J Plewka, H Lichtenegger, AC Dias‐Cabral, A Jungbauer, ... Biotechnology and bioengineering 116 (1), 76-86, 2019 | 13 | 2019 |
Viscoelasticity and structure of blood clots generated in-vitro by rheometry: A comparison between human, horse, rat, and camel C Dibiasi, J Plewka, L Ploszczanski, V Glanz, H Lichtenegger, ... Clinical hemorheology and microcirculation 69 (4), 515-531, 2018 | 13 | 2018 |
Macrocyclic Peptide Inhibitor of PD‐1/PD‐L1 Immune Checkpoint K Magiera‐Mularz, K Kuska, L Skalniak, P Grudnik, B Musielak, J Plewka, ... Advanced Therapeutics 4 (2), 2000195, 2021 | 11 | 2021 |
Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2, 2′-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors H Zhang, S Zhou, J Plewka, C Wu, M Zhu, Q Yu, B Musielak, X Wang, ... Journal of Medicinal Chemistry 66 (15), 10579-10603, 2023 | 8 | 2023 |
A computationally designed β-amino acid-containing miniprotein M Bejger, P Fortuna, M Drewniak-Świtalska, J Plewka, W Rypniewski, ... Chemical Communications 57 (49), 6015-6018, 2021 | 8 | 2021 |
Antibody binding heterogeneity of protein A resins GFL da Silva, J Plewka, R Tscheließnig, H Lichtenegger, A Jungbauer, ... Biotechnology journal 14 (8), 1800632, 2019 | 8 | 2019 |
Human and mouse PD-L1: similar molecular structure, but different druggability profiles. IScience 2021; 24: 101960 K Magiera-Mularz, J Kocik, B Musielak, J Plewka, D Sala, M Machula, ... Article CAS, 2020 | 7 | 2020 |
Design, synthesis, and biological evaluation of 2-hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 antagonist and its comparison to available small molecular PD-L1 inhibitors MA Ważyńska, R Butera, M Requesens, A Plat, T Zarganes-Tzitzikas, ... Journal of Medicinal Chemistry 66 (14), 9577-9591, 2023 | 6 | 2023 |
Despite the odds: formation of the SARS-CoV-2 methylation complex A Matsuda, J Plewka, M Rawski, A Mourão, W Zajko, T Siebenmorgen, ... Nucleic Acids Research, gkae165, 2024 | 4 | 2024 |