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Jacek Plewka
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CA-170–a potent small-molecule PD-L1 inhibitor or not?
B Musielak, J Kocik, L Skalniak, K Magiera-Mularz, D Sala, M Czub, ...
Molecules 24 (15), 2804, 2019
1242019
Di-bromo-based small-molecule inhibitors of the PD-1/PD-L1 immune checkpoint
M Konieczny, B Musielak, J Kocik, L Skalniak, D Sala, M Czub, ...
Journal of Medicinal Chemistry 63 (19), 11271-11285, 2020
552020
Terphenyl-based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein− Protein Interaction
D Muszak, E Surmiak, J Plewka, K Magiera-Mularz, J Kocik, B Musielak, ...
492021
Human and mouse PD-L1: similar molecular structure, but different druggability profiles
K Magiera-Mularz, J Kocik, B Musielak, J Plewka, D Sala, M Machula, ...
Iscience 24 (1), 2021
492021
Multicomponent peptide stapling as a diversity‐driven tool for the development of inhibitors of protein–protein interactions
MG Ricardo, AM Ali, J Plewka, E Surmiak, B Labuzek, CG Neochoritis, ...
Angewandte Chemie International Edition 59 (13), 5235-5241, 2020
382020
Design, synthesis, and biological evaluation of imidazopyridines as PD-1/PD-L1 antagonists
R Butera, M Ważyńska, K Magiera-Mularz, J Plewka, B Musielak, ...
ACS Medicinal Chemistry Letters 12 (5), 768-773, 2021
372021
TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition
MD Roganowicz, S Komurlu, S Mukherjee, J Plewka, SL Alam, ...
PLoS pathogens 13 (10), e1006686, 2017
262017
Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity
A Czarna, J Plewka, L Kresik, A Matsuda, A Karim, C Robinson, ...
Structure 30 (8), 1050-1054. e2, 2022
252022
PD-L1 inhibitors: different classes, activities, and mechanisms of action
E Surmiak, K Magiera-Mularz, B Musielak, D Muszak, J Kocik-Krol, R Kitel, ...
International Journal of Molecular Sciences 22 (21), 11797, 2021
222021
Competition NMR for detection of hit/lead inhibitors of protein–protein interactions
B Musielak, W Janczyk, I Rodriguez, J Plewka, D Sala, K Magiera-Mularz, ...
Molecules 25 (13), 3017, 2020
162020
Antibody adsorption in protein‐A affinity chromatography–in situ measurement of nanoscale structure by small‐angle X‐ray scattering
J Plewka, GL Silva, R Tscheließnig, H Rennhofer, C Dias‐Cabral, ...
Journal of separation science 41 (22), 4122-4132, 2018
142018
The pearl necklace model in protein A chromatography: Molecular mechanisms at the resin interface
G L. Silva, J Plewka, H Lichtenegger, AC Dias‐Cabral, A Jungbauer, ...
Biotechnology and bioengineering 116 (1), 76-86, 2019
132019
Viscoelasticity and structure of blood clots generated in-vitro by rheometry: A comparison between human, horse, rat, and camel
C Dibiasi, J Plewka, L Ploszczanski, V Glanz, H Lichtenegger, ...
Clinical hemorheology and microcirculation 69 (4), 515-531, 2018
132018
Macrocyclic Peptide Inhibitor of PD‐1/PD‐L1 Immune Checkpoint
K Magiera‐Mularz, K Kuska, L Skalniak, P Grudnik, B Musielak, J Plewka, ...
Advanced Therapeutics 4 (2), 2000195, 2021
112021
Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2, 2′-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors
H Zhang, S Zhou, J Plewka, C Wu, M Zhu, Q Yu, B Musielak, X Wang, ...
Journal of Medicinal Chemistry 66 (15), 10579-10603, 2023
82023
A computationally designed β-amino acid-containing miniprotein
M Bejger, P Fortuna, M Drewniak-Świtalska, J Plewka, W Rypniewski, ...
Chemical Communications 57 (49), 6015-6018, 2021
82021
Antibody binding heterogeneity of protein A resins
GFL da Silva, J Plewka, R Tscheließnig, H Lichtenegger, A Jungbauer, ...
Biotechnology journal 14 (8), 1800632, 2019
82019
Human and mouse PD-L1: similar molecular structure, but different druggability profiles. IScience 2021; 24: 101960
K Magiera-Mularz, J Kocik, B Musielak, J Plewka, D Sala, M Machula, ...
Article CAS, 2020
72020
Design, synthesis, and biological evaluation of 2-hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 antagonist and its comparison to available small molecular PD-L1 inhibitors
MA Ważyńska, R Butera, M Requesens, A Plat, T Zarganes-Tzitzikas, ...
Journal of Medicinal Chemistry 66 (14), 9577-9591, 2023
62023
Despite the odds: formation of the SARS-CoV-2 methylation complex
A Matsuda, J Plewka, M Rawski, A Mourão, W Zajko, T Siebenmorgen, ...
Nucleic Acids Research, gkae165, 2024
42024
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Articles 1–20