| Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8 KB Gorden, KS Gorski, SJ Gibson, RM Kedl, WC Kieper, X Qiu, MA Tomai, ... The Journal of Immunology 174 (3), 1259-1268, 2005 | 847 | 2005 |
| Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3 KM Lammers, R Lu, J Brownley, B Lu, C Gerard, K Thomas, ... Gastroenterology 135 (1), 194-204. e3, 2008 | 679 | 2008 |
| Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity T Querec, S Bennouna, S Alkan, Y Laouar, K Gorden, R Flavell, S Akira, ... The Journal of experimental medicine 203 (2), 413-424, 2006 | 648 | 2006 |
| Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells. V Brinkmann, T Geiger, S Alkan, CH Heusser The Journal of experimental medicine 178 (5), 1655-1663, 1993 | 617 | 1993 |
| Epitope-specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro. CA Akdis, M Akdis, T Blesken, D Wymann, SS Alkan, U Müller, K Blaser The Journal of clinical investigation 98 (7), 1676-1683, 1996 | 406 | 1996 |
| Alteration of monocyte function following major injury E Faist, A Mewes, T Strasser, A Walz, S Alkan, C Baker, W Ertel, ... Archives of surgery 123 (3), 287-292, 1988 | 352 | 1988 |
| Prostaglandin E2 (PGE2)-dependent suppression of interleukin α (IL-2) production in patients with major trauma E Faist, A Mewes, CC Baker, T Strasser, SS Alkan, P Rieber, G Heberer Journal of Trauma and Acute Care Surgery 27 (8), 837-848, 1987 | 264 | 1987 |
| Cutting edge: activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyT oligodeoxynucleotides KKB Gorden, XX Qiu, CCA Binsfeld, JP Vasilakos, SS Alkan The Journal of Immunology 177 (10), 6584-6587, 2006 | 252 | 2006 |
| Tenascin, an extracellular matrix protein, exerts immunomodulatory activities. CR Rüegg, R Chiquet-Ehrismann, SS Alkan Proceedings of the National Academy of Sciences 86 (19), 7437-7441, 1989 | 193 | 1989 |
| Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists KS Gorski, EL Waller, J Bjornton-Severson, JA Hanten, CL Riter, ... International immunology 18 (7), 1115-1126, 2006 | 192 | 2006 |
| Mice lacking the IFN-gamma receptor have impaired ability to resolve a lung eosinophilic inflammatory response associated with a prolonged capacity of T cells to exhibit a Th2 … AJ Coyle, S Tsuyuki, C Bertrand, S Huang, M Aguet, SS Alkan, ... Journal of immunology (Baltimore, Md.: 1950) 156 (8), 2680-2685, 1996 | 172 | 1996 |
| Toll-like receptor (TLR) 2–9 agonists-induced cytokines and chemokines: I. Comparison with T cell receptor-induced responses TK Ghosh, DJ Mickelson, J Fink, JC Solberg, JR Inglefield, D Hook, ... Cellular immunology 243 (1), 48-57, 2006 | 164 | 2006 |
| Monoclonal anti-gamma interferon antibodies enhance experimental allergic encephalomyelitis FD Lublin, RL Knobler, B Kalman, M Goldhaber, J Marini, M Perrault, ... Autoimmunity 16 (4), 267-274, 1993 | 163 | 1993 |
| Genetic reprogramming of primary human T cells reveals functional plasticity in Th cell differentiation MS Sundrud, SM Grill, D Ni, K Nagata, SS Alkan, A Subramaniam, ... The Journal of Immunology 171 (7), 3542-3549, 2003 | 153 | 2003 |
| Comparison of human B cell activation by TLR7 and TLR9 agonists JA Hanten, JP Vasilakos, CL Riter, L Neys, KE Lipson, SS Alkan, ... BMC immunology 9, 1-15, 2008 | 148 | 2008 |
| Inhibition of T helper 2‐type responses, IgE production and eosinophilia by synthetic lipopeptides CA Akdis, F Kussebi, B Pulendran, M Akdis, RP Lauener, ... European journal of immunology 33 (10), 2717-2726, 2003 | 146 | 2003 |
| ANTIGEN RECOGNITION AND THE IMMUNE RESPONSE: HUMORAL AND CELLULAR IMMUNE RESPONSES TO SMALL MONO- AND BIFUNCTIONAL ANTIGEN M … SS Alkan, EB Williams, DE Nitecki, JW Goodman The Journal of Experimental Medicine 135 (6), 1228-1246, 1972 | 137 | 1972 |
| Monoclonal antibodies: the story of a discovery that revolutionized science and medicine SS Alkan Nature Reviews Immunology 4 (2), 153-156, 2004 | 130 | 2004 |
| TLR–TLR cross talk in human PBMC resulting in synergistic and antagonistic regulation of type-1 and 2 interferons, IL-12 and TNF-α TK Ghosh, DJ Mickelson, JC Solberg, KE Lipson, JR Inglefield, SS Alkan International immunopharmacology 7 (8), 1111-1121, 2007 | 126 | 2007 |
| Larazotide acetate regulates epithelial tight junctions in vitro and in vivo S Gopalakrishnan, M Durai, K Kitchens, AP Tamiz, R Somerville, M Ginski, ... Peptides 35 (1), 86-94, 2012 | 125 | 2012 |
Cezmi AkdisUniversity Zurich, Swiss Institute of Allergy and Asthma Research (SIAF), Davos, SwitzerlandVerified email at siaf.uzh.ch
