Pulmonary delivery of therapeutic siRNA JKW Lam, W Liang, HK Chan Advanced drug delivery reviews 64 (1), 1-15, 2012 | 268 | 2012 |
Endosomal escape pathways for non-viral nucleic acid delivery systems W Liang, JKW Lam Molecular regulation of endocytosis 2, 64, 2012 | 165 | 2012 |
Pulmonary delivery of biological drugs W Liang, HW Pan, D Vllasaliu, JKW Lam Pharmaceutics 12 (11), 1025, 2020 | 104 | 2020 |
Delivery of RNAi therapeutics to the airways—from bench to bedside Y Qiu, JKW Lam, SWS Leung, W Liang Molecules 21 (9), 1249, 2016 | 70 | 2016 |
Spray freeze drying of small nucleic acids as inhaled powder for pulmonary delivery W Liang, AYL Chan, MYT Chow, FFK Lo, Y Qiu, PCL Kwok, JKW Lam asian journal of pharmaceutical sciences 13 (2), 163-172, 2018 | 58 | 2018 |
Inhalable dry powder formulations of siRNA and pH-responsive peptides with antiviral activity against H1N1 influenza virus W Liang, MYT Chow, PN Lau, QT Zhou, PCL Kwok, GPH Leung, ... Molecular pharmaceutics 12 (3), 910-921, 2015 | 57 | 2015 |
Formulation of pH responsive peptides as inhalable dry powders for pulmonary delivery of nucleic acids W Liang, PCL Kwok, MYT Chow, P Tang, AJ Mason, HK Chan, JKW Lam European Journal of Pharmaceutics and Biopharmaceutics 86 (1), 64-73, 2014 | 56 | 2014 |
Effective endogenous gene silencing mediated by pH responsive peptides proceeds via multiple pathways JKW Lam, W Liang, Y Lan, P Chaudhuri, MYT Chow, K Witt, L Kudsiova, ... Journal of controlled release 158 (2), 293-303, 2012 | 52 | 2012 |
Incorporation of a nuclear localization signal in pH responsive LAH4-L1 peptide enhances transfection and nuclear uptake of plasmid DNA Y Xu, W Liang, Y Qiu, M Cespi, GF Palmieri, AJ Mason, JKW Lam Molecular pharmaceutics 13 (9), 3141-3152, 2016 | 48 | 2016 |
Using two-fluid nozzle for spray freeze drying to produce porous powder formulation of naked siRNA for inhalation W Liang, MYT Chow, SF Chow, HK Chan, PCL Kwok, JKW Lam International journal of pharmaceutics 552 (1-2), 67-75, 2018 | 45 | 2018 |
From pulmonary surfactant, synthetic KL4 peptide as effective siRNA delivery vector for pulmonary delivery Y Qiu, MYT Chow, W Liang, WWY Chung, JCW Mak, JKW Lam Molecular Pharmaceutics 14 (12), 4606-4617, 2017 | 40 | 2017 |
Synthesis, structure–activity relationships and in vitro toxicity profile of lactose-based fatty acid monoesters as possible drug permeability enhancers S Lucarini, L Fagioli, R Cavanagh, W Liang, DR Perinelli, M Campana, ... Pharmaceutics 10 (3), 81, 2018 | 34 | 2018 |
DNA-loaded chitosan oligosaccharide nanoparticles with enhanced permeability across Calu-3 cells Y Ye, Y Xu, W Liang, GPH Leung, KH Cheung, C Zheng, F Chen, ... Journal of Drug Targeting 21 (5), 474-486, 2013 | 23 | 2013 |
Western blot evaluation of siRNA delivery by pH-responsive peptides W Liang, AJ Mason, JKW Lam Target Identification and Validation in Drug Discovery: Methods and …, 2013 | 17 | 2013 |
Manipulating the pH response of 2, 3-diaminopropionic acid rich peptides to mediate highly effective gene silencing with low-toxicity V Abbate, W Liang, J Patel, Y Lan, L Capriotti, V Iacobucci, TT Bui, ... Journal of controlled release 172 (3), 929-938, 2013 | 10 | 2013 |
Development of carrier-free, inhalable powder formulation of siRNA therapeutics for the treatment of respiratory diseases JK Lam, W Liang, MY Chow Proceedings for Annual Meeting of The Japanese Pharmacological Society …, 2018 | | 2018 |
Inhibition of influenza viral replication using siRNA delivered by pH-responsive peptides W Liang, PN Lau, J Mason, LLM Poon, JKW Lam Annual RNAi International Conference and Exhibition, RNAi 2013, 2013 | | 2013 |
Spray and spray freeze dried powders containing pH responsive peptides and mannitol as DNA carriers for pulmonary delivery W Liang, PCL Kwok, YT CHOW, AJ Mason, HK Chan, JKW Lam Respiratory Drug Delivery Conference, RDD 2013 Proceedings, 2013 | | 2013 |
Formulation of siRNA with pH-responsive amphipathic peptides for inhalation against respiratory infectious diseases W Liang, AJ Mason, HK Chan, LLM Poon, JKW Lam Research Postgraduate Symposium, RPS 2013, 2013 | | 2013 |
Design of dry powder formulations of pH responsive peptide/plasmid DNA complexes for pulmonary delivery W Liang, PCL Kwok, YT Chow, P Tang, AJ Mason, HK Chan, JKW Lam Inhalation Asia Conference, 2013 | | 2013 |