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Jianbin Zheng
Jianbin Zheng
Vanqua Bio
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Title
Cited by
Cited by
Year
Anticarcinogenic and antioxidant activity of diindolylmethane derivatives
SH Benabadji, R Wen, JB Zheng, XC Dong, SG Yuan
Acta Pharmacologica Sinica 25 (5), 666-671, 2004
1752004
A modulator of wild-type glucocerebrosidase improves pathogenic phenotypes in dopaminergic neuronal models of Parkinson’s disease
LF Burbulla, S Jeon, J Zheng, P Song, RB Silverman, D Krainc
Science translational medicine 11 (514), eaau6870, 2019
962019
Progranulin mutations result in impaired processing of prosaposin and reduced glucocerebrosidase activity
C Valdez, D Ysselstein, TJ Young, J Zheng, D Krainc
Human molecular genetics 29 (5), 716-726, 2020
612020
Characterization of a novel curcumin analog P1 as potent inhibitor of the NF-κB signaling pathway with distinct mechanisms
Y Peng, J Zheng, Y Zhou, J Li
Acta Pharmacologica Sinica 34 (7), 939-950, 2013
422013
β-Glucocerebrosidase modulators promote dimerization of β-glucocerebrosidase and reveal an allosteric binding site
J Zheng, L Chen, OS Skinner, D Ysselstein, J Remis, P Lansbury, R Skerlj, ...
Journal of the American Chemical Society 140 (18), 5914-5924, 2018
342018
Substituted 4-methyl-pyrrolo [1, 2-A] pyrimidine-8-carboxamide compounds and uses thereof for modulating glucocerebrosidase activity
D Krainc, RB Silverman, J Zheng
US Patent 9,802,942, 2017
262017
Substituted quinazoline compounds and uses thereof for modulating glucocerebrosidase activity
D Krainc, RB Silverman, J Zheng
US Patent 10,167,270, 2019
252019
Direct synthesis of β-N-glycosides by the reductive glycosylation of azides with protected and native carbohydrate donors
J Zheng, KB Urkalan, SB Herzon
Angewandte Chemie (International ed. in English) 52 (23), 6068, 2013
252013
Design and Synthesis of Potent Quinazolines as Selective β-Glucocerebrosidase Modulators
DK Jianbin Zheng, Long Chen, Michael Schwake, Richard B. Silverman
Journal of Medicinal Chemistry 59 (18), 8508–8520, 2016
242016
Conversion of quinazoline modulators from inhibitors to activators of β-glucocerebrosidase
J Zheng, S Jeon, W Jiang, LF Burbulla, D Ysselstein, K Oevel, D Krainc, ...
Journal of medicinal chemistry 62 (3), 1218-1230, 2019
222019
Synthesis of 1-indole substituted beta-carboline alkaloid and its derivatives and evaluation of their preliminary antitumor activities. 2004, 39(4): 259-262.
X Dong, R Wen, J Zheng
Acta Pharmaceutica Sinica. 39 (4), 259-262, 2004
22*2004
Design, synthesis, and biological evaluation of the N,N-diarylalkenyl-piperidinecarboxylic acid derivatives as GABA uptake inhibitors (I)
J Zheng, R Wen, X Luo, G Lin, J Zhang, L Xu, L Guo, H Jiang
Bioorganic & medicinal chemistry letters 16 (1), 225-227, 2006
192006
Discovery of di-indolinone as a novel scaffold for protein tyrosine phosphatase 1B inhibitors
H Dai, L Gao, Y Yang, J Li, J Cheng, J Li, R Wen, Y Peng, J Zheng
Bioorganic & medicinal chemistry letters 22 (24), 7440-7443, 2012
132012
Substituted pyrrolo [1, 2-a] pyrimidines and their use in the treatment of medical disorders
RT Skerlj, PT Lansbury, AC Good, EMJ Bourque, RB Silverman, D Krainc, ...
US Patent 10,751,341, 2020
122020
Synthesis and biological evaluation of novel indolin-2-one derivatives as protein tyrosine phosphatase 1B inhibitors
HL Dai, Q Shen, JB Zheng, JY Lib, R Wen, J Li
Letters in Organic Chemistry 8 (7), 526-530, 2011
122011
Synthesis and antitumor activities of 3-substituted 1-(5-formylfurfuryl) indolin-2-one derivatives
F Zhou, J Zheng, X Dong, Z Zhang, L Zhao, X Sha, L Li, R Wen
Letters in Organic Chemistry 4 (8), 601-605, 2007
122007
Substituted 4-methyl-pyrrolo [1, 2-A] pyrimidine-8-carboxamide compounds and uses thereof for modulating glucocerebrosidase activity
D Krainc, RB Silverman, J Zheng
US Patent 10,040,799, 2018
112018
Three-dimensional quantitative structure-activity relationship (CoMFA and CoMSIA) studies on galardin derivatives as gelatinase A (matrix metalloproteinase 2) inhibitors
J Zheng, R Wen, D Guillaume
Journal of Enzyme Inhibition and Medicinal Chemistry 23 (4), 445-453, 2008
102008
Synthesis of 1-indole substituted beta-carboline alkaloid and its derivatives and evaluation of their preliminary antitumor activities
X Dong, R Wen, J Zheng
Acta Pharmaceutica Sinica, 259-262, 2004
102004
Substituted 4-methyl-pyrrolo [1, 2-a] pyrimidine-8-carboxamide compounds and uses thereof for modulating glucocerebrosidase activity
D Krainc, RB Silverman, J Zheng
US Patent 10,442,812, 2019
92019
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