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Georg Kuenze
Georg Kuenze
Junior Research Group Leader, Institute for Drug Discovery, Leipzig University
Verified email at uni-leipzig.de - Homepage
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Cited by
Cited by
Year
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
5622020
The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors
L Joedicke, J Mao, G Kuenze, C Reinhart, T Kalavacherla, HRA Jonker, ...
Nature chemical biology 14 (3), 284-290, 2018
882018
Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein
G Künze, P Barré, HA Scheidt, L Thomas, D Eliezer, D Huster
Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (9), 2302-2313, 2012
862012
Mechanisms of KCNQ1 channel dysfunction in long QT syndrome involving voltage sensor domain mutations
H Huang, G Kuenze, JA Smith, KC Taylor, AM Duran, A Hadziselimovic, ...
Science advances 4 (3), eaar2631, 2018
762018
Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state
KC Taylor, PW Kang, P Hou, ND Yang, G Kuenze, JA Smith, J Shi, ...
Elife 9, e53901, 2020
372020
Chemoenzymatic synthesis of nonasulfated tetrahyaluronan with a paramagnetic tag for studying its complex with interleukin‐10
S Köhling, G Künze, K Lemmnitzer, M Bermudez, G Wolber, J Schiller, ...
Chemistry–A European Journal 22 (16), 5563-5574, 2016
362016
Identification of the glycosaminoglycan binding site of interleukin-10 by NMR spectroscopy
G Künze, S Köhling, A Vogel, J Rademann, D Huster
Journal of Biological Chemistry 291 (6), 3100-3113, 2016
362016
NMR characterization of the binding properties and conformation of glycosaminoglycans interacting with interleukin-10
G Künze, JP Gehrcke, MT Pisabarro, D Huster
Glycobiology 24 (11), 1036-1049, 2014
342014
Modeling immunity with rosetta: Methods for antibody and antigen design
CT Schoeder, S Schmitz, J Adolf-Bryfogle, AM Sevy, JA Finn, MF Sauer, ...
Biochemistry 60 (11), 825-846, 2021
292021
Regulation of an intracellular subtilisin protease activity by a short propeptide sequence through an original combined dual mechanism
M Gamble, G Künze, EJ Dodson, KS Wilson, DD Jones
Proceedings of the National Academy of Sciences 108 (9), 3536-3541, 2011
282011
Integrative protein modeling in RosettaNMR from sparse paramagnetic restraints
G Kuenze, R Bonneau, JK Leman, J Meiler
Structure 27 (11), 1721-1734. e5, 2019
252019
Upgraded molecular models of the human KCNQ1 potassium channel
G Kuenze, AM Duran, H Woods, KR Brewer, EF McDonald, CG Vanoye, ...
PloS one 14 (9), e0220415, 2019
252019
Structures illuminate cardiac ion channel functions in health and in long QT syndrome
KR Brewer, G Kuenze, CG Vanoye, AL George Jr, J Meiler, CR Sanders
Frontiers in Pharmacology 11, 550, 2020
242020
Integrated structural modeling of full-length LRH-1 reveals inter-domain interactions contribute to receptor structure and function
CD Seacrist, G Kuenze, RM Hoffmann, BE Moeller, JE Burke, J Meiler, ...
Structure 28 (7), 830-846. e9, 2020
232020
Crystal structure of an intracellular subtilisin reveals novel structural features unique to this subtilisin family
J Vevodova, M Gamble, G Künze, A Ariza, E Dodson, DD Jones, ...
Structure 18 (6), 744-755, 2010
222010
Structure and function of the metagenomic plastic-degrading polyester hydrolase PHL7 bound to its product
PK Richter, P Blázquez-Sánchez, Z Zhao, F Engelberger, C Wiebeler, ...
Nature Communications 14 (1), 1905, 2023
212023
Structure and Function of the Transmembrane Domain of NsaS, an Antibiotic Sensing Histidine Kinase in Staphylococcus aureus
MP Bhate, T Lemmin, G Kuenze, B Mensa, S Ganguly, JM Peters, ...
Journal of the American Chemical Society 140 (24), 7471-7485, 2018
212018
Site-specific dynamic nuclear polarization in a Gd (III)-labeled protein
J Heiliger, T Matzel, EC Çetiner, H Schwalbe, G Kuenze, B Corzilius
Physical Chemistry Chemical Physics 22 (44), 25455-25466, 2020
202020
Investigation of the structure of regulatory proteins interacting with glycosaminoglycans by combining NMR spectroscopy and molecular modeling–the beginning of a wonderful …
G Künze, D Huster, SA Samsonov
Biological chemistry 402 (11), 1337-1355, 2021
192021
Structural determinants of cholesterol recognition in helical integral membrane proteins
B Marlow, G Kuenze, B Li, CR Sanders, J Meiler
Biophysical journal 120 (9), 1592-1604, 2021
182021
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