Dipicolinic acid derivatives as inhibitors of New Delhi metallo-β-lactamase-1 AY Chen, PW Thomas, AC Stewart, A Bergstrom, Z Cheng, C Miller, ... Journal of medicinal chemistry 60 (17), 7267-7283, 2017 | 148 | 2017 |
The continuing challenge of metallo-β-lactamase inhibition: mechanism matters LC Ju, Z Cheng, W Fast, RA Bonomo, MW Crowder Trends in pharmacological sciences 39 (7), 635-647, 2018 | 134 | 2018 |
Evolution of New Delhi metallo-β-lactamase (NDM) in the clinic: effects of NDM mutations on stability, zinc affinity, and mono-zinc activity Z Cheng, PW Thomas, L Ju, A Bergstrom, K Mason, D Clayton, C Miller, ... Journal of Biological Chemistry 293 (32), 12606-12618, 2018 | 94 | 2018 |
Copper binding in IscA inhibits iron‐sulphur cluster assembly in Escherichia coli G Tan, Z Cheng, Y Pang, AP Landry, J Li, J Lu, H Ding Molecular microbiology 93 (4), 629-644, 2014 | 74 | 2014 |
Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7 A Bergstrom, A Katko, Z Adkins, J Hill, Z Cheng, M Burnett, H Yang, ... ACS infectious diseases 4 (2), 135-145, 2018 | 57 | 2018 |
Clinical variants of New Delhi metallo-β-lactamase are evolving to overcome zinc scarcity AC Stewart, CR Bethel, J VanPelt, A Bergstrom, Z Cheng, CG Miller, ... ACS infectious diseases 3 (12), 927-940, 2017 | 56 | 2017 |
Reduction of mitochondrial protein mitoNEET [2Fe–2S] clusters by human glutathione reductase AP Landry, Z Cheng, H Ding Free Radical Biology and Medicine 81, 119-127, 2015 | 50 | 2015 |
Binding of nitric oxide in CDGSH-type [2Fe-2S] clusters of the human mitochondrial protein Miner2 Z Cheng, AP Landry, Y Wang, H Ding Journal of Biological Chemistry 292 (8), 3146-3153, 2017 | 36 | 2017 |
Iron binding activity is essential for the function of IscA in iron–sulphur cluster biogenesis AP Landry, Z Cheng, H Ding Dalton Transactions 42 (9), 3100-3106, 2013 | 33 | 2013 |
Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo‐β‐Lactamases AY Chen, PW Thomas, Z Cheng, NY Xu, DL Tierney, MW Crowder, ... ChemMedChem 14 (13), 1271-1282, 2019 | 31 | 2019 |
Flavin nucleotides act as electron shuttles mediating reduction of the [2Fe-2S] clusters in mitochondrial outer membrane protein mitoNEET AP Landry, Y Wang, Z Cheng, RB Crochet, YH Lee, H Ding Free Radical Biology and Medicine 102, 240-247, 2017 | 27 | 2017 |
Probing the mechanisms of inhibition for various inhibitors of metallo-β-lactamases VIM-2 and NDM-1 CA Thomas, Z Cheng, K Yang, E Hellwarth, CJ Yurkiewicz, FM Baxter, ... Journal of Inorganic Biochemistry 210, 111123, 2020 | 24 | 2020 |
Carbapenem use is driving the evolution of imipenemase 1 variants Z Cheng, CR Bethel, PW Thomas, BA Shurina, JP Alao, CA Thomas, ... Antimicrobial Agents and Chemotherapy 65 (4), 10.1128/aac. 01714-20, 2021 | 23 | 2021 |
Stimulation of Escherichia coli DNA damage inducible DNA helicase DinG by the single-stranded DNA binding protein SSB Z Cheng, A Caillet, B Ren, H Ding FEBS letters 586 (21), 3825-3830, 2012 | 22 | 2012 |
Visualizing the dynamic metalation state of New Delhi metallo-β-lactamase-1 in bacteria using a reversible fluorescent probe R Mehta, DD Rivera, DJ Reilley, D Tan, PW Thomas, A Hinojosa, ... Journal of the American Chemical Society 143 (22), 8314-8323, 2021 | 21 | 2021 |
Iminodiacetic Acid as a Novel Metal‐Binding Pharmacophore for New Delhi Metallo‐β‐lactamase Inhibitor Development AY Chen, CA Thomas, PW Thomas, K Yang, Z Cheng, W Fast, ... ChemMedChem 15 (14), 1272-1282, 2020 | 21 | 2020 |
A single salt bridge in VIM-20 increases protein stability and antibiotic resistance under low-zinc conditions Z Cheng, BA Shurina, CR Bethel, PW Thomas, SH Marshall, CA Thomas, ... Mbio 10 (6), 10.1128/mbio. 02412-19, 2019 | 18 | 2019 |
MBlinhibitors. com, a website resource offering information and expertise for the continued development of metallo-β-lactamase inhibitors Z Cheng, CA Thomas, AR Joyner, RL Kimble, AM Sturgill, NY Tran, ... Biomolecules 10 (3), 459, 2020 | 15 | 2020 |
Analysis of barrel-aged Kentucky bourbon whiskey by ultrahigh resolution mass spectrometry K Yang, A Somogyi, C Thomas, H Zhang, Z Cheng, S Xu, C Miller, ... Food Analytical Methods 13, 2301-2311, 2020 | 14 | 2020 |
Elusive structural changes of New Delhi metallo-β-lactamase revealed by ultraviolet photodissociation mass spectrometry MR Mehaffey, YC Ahn, DD Rivera, PW Thomas, Z Cheng, MW Crowder, ... Chemical Science 11 (33), 8999-9010, 2020 | 13 | 2020 |