Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain DJ Cua, J Sherlock, YI Chen, CA Murphy, B Joyce, B Seymour, L Lucian, ... Nature 421 (6924), 744-748, 2003 | 3802 | 2003 |
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo MJ McGeachy, Y Chen, CM Tato, A Laurence, B Joyce-Shaikh, ... Nature immunology 10 (3), 314-324, 2009 | 1286 | 2009 |
IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells JP Sherlock, B Joyce-Shaikh, SP Turner, CC Chao, M Sathe, J Grein, ... Nature medicine 18 (7), 1069-1076, 2012 | 1164 | 2012 |
Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology HH Uhlig, BS McKenzie, S Hue, C Thompson, B Joyce-Shaikh, ... Immunity 25 (2), 309-318, 2006 | 813 | 2006 |
Anti–IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis Y Chen, CL Langrish, B Mckenzie, B Joyce-Shaikh, JS Stumhofer, ... The Journal of clinical investigation 116 (5), 1317-1326, 2006 | 777 | 2006 |
Interleukin-23-independent IL-17 production regulates intestinal epithelial permeability JS Lee, CM Tato, B Joyce-Shaikh, MF Gulen, C Cayatte, Y Chen, ... Immunity 43 (4), 727-738, 2015 | 671 | 2015 |
IL-25 regulates Th17 function in autoimmune inflammation MA Kleinschek, AM Owyang, B Joyce-Shaikh, CL Langrish, Y Chen, ... The Journal of experimental medicine 204 (1), 161-170, 2007 | 530 | 2007 |
IL-17 regulates adipogenesis, glucose homeostasis, and obesity LA Zúñiga, WJ Shen, B Joyce-Shaikh, EA Pyatnova, AG Richards, ... The Journal of Immunology 185 (11), 6947-6959, 2010 | 449 | 2010 |
IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells C Diveu, MJ McGeachy, K Boniface, JS Stumhofer, M Sathe, ... The Journal of Immunology 182 (9), 5748-5756, 2009 | 443 | 2009 |
The CD200 receptor is a novel and potent regulator of murine and human mast cell function HM Cherwinski, CA Murphy, BL Joyce, ME Bigler, YS Song, SM Zurawski, ... the Journal of Immunology 174 (3), 1348-1356, 2005 | 169 | 2005 |
Interleukin-23-induced transcription factor Blimp-1 promotes pathogenicity of T helper 17 cells R Jain, Y Chen, Y Kanno, B Joyce-Shaikh, G Vahedi, K Hirahara, ... Immunity 44 (1), 131-142, 2016 | 159 | 2016 |
LAG3+ regulatory T cells restrain interleukin-23-producing CX3CR1+ gut-resident macrophages during group 3 innate lymphoid cell-driven colitis D Bauché, B Joyce-Shaikh, R Jain, J Grein, KS Ku, WM Blumenschein, ... Immunity 49 (2), 342-352. e5, 2018 | 154 | 2018 |
IL-23 is required for the development of severe egg-induced immunopathology in schistosomiasis and for lesional expression of IL-17 LI Rutitzky, L Bazzone, MG Shainheit, B Joyce-Shaikh, DJ Cua, ... The Journal of Immunology 180 (4), 2486-2495, 2008 | 144 | 2008 |
Dual roles for regulatory T-cell depletion and costimulatory signaling in agonistic GITR targeting for tumor immunotherapy AE Mahne, S Mauze, B Joyce-Shaikh, J Xia, EP Bowman, AM Beebe, ... Cancer research 77 (5), 1108-1118, 2017 | 128 | 2017 |
Autoimmune memory T helper 17 cell function and expansion are dependent on interleukin-23 CJ Haines, Y Chen, WM Blumenschein, R Jain, C Chang, B Joyce-Shaikh, ... Cell reports 3 (5), 1378-1388, 2013 | 101 | 2013 |
Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis B Joyce-Shaikh, ME Bigler, CC Chao, EE Murphy, WM Blumenschein, ... Journal of Experimental Medicine 207 (3), 579-589, 2010 | 87 | 2010 |
Biomarkers of therapeutic response in the IL-23 pathway in inflammatory bowel disease C Cayatte, B Joyce-Shaikh, F Vega, K Boniface, J Grein, E Murphy, ... Clinical and translational gastroenterology 3 (2), e10, 2012 | 57 | 2012 |
Inhibition of RORγT skews TCRα gene rearrangement and limits T cell repertoire diversity Y Guo, KD MacIsaac, Y Chen, RJ Miller, R Jain, B Joyce-Shaikh, ... Cell reports 17 (12), 3206-3218, 2016 | 52 | 2016 |
GITR Agonism Enhances Cellular Metabolism to Support CD8+ T-cell Proliferation and Effector Cytokine Production in a Mouse Tumor Model SS Sabharwal, DB Rosen, J Grein, D Tedesco, B Joyce-Shaikh, R Ueda, ... Cancer Immunology Research 6 (10), 1199-1211, 2018 | 48 | 2018 |
ILT3 (LILRB4) promotes the immunosuppressive function of tumor-educated human monocytic myeloid-derived suppressor cells L Singh, ES Muise, A Bhattacharya, J Grein, S Javaid, P Stivers, J Zhang, ... Molecular cancer research 19 (4), 702-716, 2021 | 36 | 2021 |