Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening O Abian, D Ortega-Alarcon, A Jimenez-Alesanco, L Ceballos-Laita, ... International journal of biological macromolecules 164, 1693-1703, 2020 | 260 | 2020 |
Identification of a drug targeting an intrinsically disordered protein involved in pancreatic adenocarcinoma JL Neira, J Bintz, M Arruebo, B Rizzuti, T Bonacci, S Vega, A Lanas, ... Scientific reports 7 (1), 39732, 2017 | 131 | 2017 |
Targeting intrinsically disordered proteins involved in cancer P Santofimia-Castaño, B Rizzuti, Y Xia, O Abian, L Peng, ... Cellular and Molecular Life Sciences 77, 1695-1707, 2020 | 94 | 2020 |
Multiple binding modes of ibuprofen in human serum albumin identified by absolute binding free energy calculations S Evoli, DL Mobley, R Guzzi, B Rizzuti Physical Chemistry Chemical Physics 18 (47), 32358-32368, 2016 | 91 | 2016 |
Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis P Santofimia-Castaño, Y Xia, W Lan, Z Zhou, C Huang, L Peng, ... The Journal of clinical investigation 129 (6), 2500-2513, 2019 | 85 | 2019 |
Using simulations to provide the framework for experimental protein folding studies B Rizzuti, V Daggett Archives of biochemistry and biophysics 531 (1-2), 128-135, 2013 | 72 | 2013 |
Rutin is a low micromolar inhibitor of SARS-CoV-2 main protease 3CLpro: Implications for drug design of quercetin analogs B Rizzuti, F Grande, F Conforti, A Jimenez-Alesanco, L Ceballos-Laita, ... Biomedicines 9 (4), 375, 2021 | 67 | 2021 |
Identification by Molecular Docking of Homoisoflavones from Leopoldia comosa as Ligands of Estrogen Receptors F Grande, B Rizzuti, MA Occhiuzzi, G Ioele, T Casacchia, F Gelmini, ... Molecules 23 (4), 894, 2018 | 63 | 2018 |
Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of Mpro and Its Antiviral Activity in Cells against SARS-CoV-2 F Mangiavacchi, P Botwina, E Menichetti, L Bagnoli, O Rosati, F Marini, ... International journal of molecular sciences 22 (13), 7048, 2021 | 62 | 2021 |
Early stage aggregation of human serum albumin in the presence of metal ions A Stirpe, M Pantusa, B Rizzuti, L Sportelli, R Bartucci, R Guzzi International journal of biological macromolecules 49 (3), 337-342, 2011 | 56 | 2011 |
Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B P Santofimia-Castaño, B Rizzuti, ÁL Pey, P Soubeyran, M Vidal, R Urrutia, ... Proceedings of the National Academy of Sciences 114 (31), E6332-E6341, 2017 | 55 | 2017 |
Stability of trans-Resveratrol Associated with Transport Proteins M Pantusa, R Bartucci, B Rizzuti Journal of agricultural and food chemistry 62 (19), 4384-4391, 2014 | 46 | 2014 |
Thermally induced denaturation and aggregation of BLG-A: effect of the Cu2+ and Zn2+ metal ions A Stirpe, B Rizzuti, M Pantusa, R Bartucci, L Sportelli, R Guzzi European Biophysics Journal 37, 1351-1360, 2008 | 45 | 2008 |
CCR5/CXCR4 dual antagonism for the improvement of HIV infection therapy F Grande, MA Occhiuzzi, B Rizzuti, G Ioele, M De Luca, P Tucci, V Svicher, ... Molecules 24 (3), 550, 2019 | 40 | 2019 |
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) F Cirillo, R Lappano, L Bruno, B Rizzuti, F Grande, R Guzzi, S Briguori, ... Journal of Experimental & Clinical Cancer Research 38, 1-18, 2019 | 39 | 2019 |
Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization J Ceramella, A Caruso, MA Occhiuzzi, D Iacopetta, A Barbarossa, ... European Journal of Medicinal Chemistry 181, 111583, 2019 | 38 | 2019 |
Determinants of the pKa values of ionizable residues in an intrinsically disordered protein JL Neira, B Rizzuti, JL Iovanna Archives of Biochemistry and Biophysics 598, 18-27, 2016 | 38 | 2016 |
Stereoselective and domain-specific effects of ibuprofen on the thermal stability of human serum albumin A Guglielmelli, B Rizzuti, R Guzzi European Journal of Pharmaceutical Sciences 112, 122-131, 2018 | 37 | 2018 |
Fatty acid binding into the highest affinity site of human serum albumin observed in molecular dynamics simulation B Rizzuti, R Bartucci, L Sportelli, R Guzzi Archives of biochemistry and biophysics 579, 18-25, 2015 | 37 | 2015 |
ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents W Lan, P Santofimia-Castaño, M Swayden, Y Xia, Z Zhou, S Audebert, ... JCI insight 5 (18), 2020 | 36 | 2020 |