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Dr Isabel Castanho
Dr Isabel Castanho
BIDMC, Harvard Medical School
Verified email at bidmc.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing
SK Leung, AR Jeffries, I Castanho, BT Jordan, K Moore, JP Davies, ...
Cell reports 37 (7), 2021
862021
Transcriptional signatures of tau and amyloid neuropathology
I Castanho, TK Murray, E Hannon, A Jeffries, E Walker, E Laing, H Baulf, ...
Cell reports 30 (6), 2040-2054. e5, 2020
522020
Characterizing the properties of bisulfite sequencing data: maximizing power and sensitivity to identify between-group differences in DNA methylation
D Seiler Vellame, I Castanho, A Dahir, J Mill, E Hannon
BMC genomics 22, 1-16, 2021
172021
Phospholipase D1 ablation disrupts mouse longitudinal hippocampal axis organization and functioning
L Santa-Marinha, I Castanho, RR Silva, FV Bravo, AM Miranda, T Meira, ...
Cell reports 30 (12), 4197-4208. e6, 2020
172020
Epigenetic processes in Alzheimer's disease
I Castanho, K Lunnon
Chromatin Signaling and Neurological Disorders, 153-180, 2019
122019
Full-length transcript sequencing of human and mouse identifies widespread isoform diversity and alternative splicing in the cerebral cortex
AR Jeffries, SK Leung, I Castanho, K Moore, JP Davies, EL Dempster, ...
bioRxiv, 2020.10. 14.339200, 2020
82020
The Neuroepigenetic Landscape of Vertebrate and Invertebrate Models of Neurodegenerative Diseases
TH Sundaramoorthy, I Castanho
Epigenetics Insights 15, 25168657221135848, 2022
42022
Transcriptional signatures of tau and amyloid neuropathology. Cell Rep 30: 2040–2054. e5
I Castanho, TK Murray, E Hannon, A Jeffries, E Walker, E Laing, H Baulf, ...
42020
Novel CYP1B1-RMDN2 Alzheimer’s disease locus identified by genome-wide association analysis of cerebral tau deposition on PET
K Nho, SL Risacher, L Apostolova, PJ Bice, J Brosch, R Deardorff, ...
medRxiv, 2023.02. 27.23286048, 2023
22023
Long-read transcript sequencing identifies differential isoform expression in the entorhinal cortex in a transgenic model of tau pathology
SK Leung, AR Jeffries, I Castanho, RA Bamford, K Moore, EL Dempster, ...
bioRxiv, 2023.09. 20.558220, 2023
12023
Understanding Alzheimer’s disease resilience at the cellular level
I Castanho, PN Yeganeh, S Shah, D Prokopenko, R Tanzi, W Hide, ...
Alzheimer's Association International Conference, 2022
12022
Functional genomic characterisation of animal models of AD: relevance to human dementia
I Castanho
PQDT-UK & Ireland, 2019
12019
Transcriptional signatures of progressive neuropathology in transgenic tau and amyloid mouse models
I Castanho, TK Murray, E Hannon, A Jeffries, E Walker, E Laing, H Baulf, ...
bioRxiv, 548578, 2019
12019
Epigenetic insights into neuropsychiatric and cognitive symptoms in Parkinson's disease: A DNA co-methylation network analysis
K Lunnon, J Harvey, A Smith, L Weymouth, R Smith, I Castanho, ...
2023
Isoform characterisation & splicing signatures of AD-risk genes using long-read sequencing
SK Leung, I Castanho, A Jeffries, K Moore, E Dempster, JT Brown, ...
Alzheimer's Association International Conference, 2023
2023
Novel CYP1B1-RMDN2 Alzheimer’s disease locus identified by genome-wide association analysis of cerebral tau deposition on PET in 3,136 individuals from 12 …
K Nho, SL Risacher, LG Apostolova, PJ Bice, JR Brosch, R Deardorff, ...
Alzheimer's Association International Conference, 2023
2023
Epigenetic insights into neuropsychiatric and cognitive symptoms in Parkinson's disease: A DNA co-methylation network analysis
J Harvey, AR Smith, LS Weymouth, RG Smith, I Castanho, L Hubbard, ...
bioRxiv, 2023.07. 20.549825, 2023
2023
Fluorescence-activated nuclei sorting (FANS) of purified neural cell populations from mouse cortex for multi-omic profiling
SS Policicchio, I Castanho, B Chioza, J Burrage, J Mill, EL Dempster, ...
2022
Global shifts in DNA methylation and DNA hydroxymethylation across multiple brain regions in transgenic models of tau and amyloid pathology: Molecular and cell biology/others
I Castanho, TK Murray, J Harvey, SK Leung, K Lunnon, Z Ahmed, J Mill
Alzheimer's & Dementia 16, e045877, 2020
2020
Genome‐wide DNA methylation signatures of tau and amyloid neuropathology: Genetics: Genetics of cognitive aging, other dementia, and endophenotypes
I Castanho, TK Murray, SK Leung, E Hannon, A Jeffries, K Lunnon, ...
Alzheimer's & Dementia 16, e045864, 2020
2020
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