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Douglas R. Hurst
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Year
Defining the hallmarks of metastasis
DR Welch, DR Hurst
Cancer research 79 (12), 3011-3027, 2019
5792019
Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis
DR Hurst, MD Edmonds, GK Scott, CC Benz, KS Vaidya, DR Welch
Cancer research 69 (4), 1279-1283, 2009
5112009
Metastamir: the field of metastasis-regulatory microRNA is spreading
DR Hurst, MD Edmonds, DR Welch
Cancer research 69 (19), 7495-7498, 2009
3892009
Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy
KT Nash, PA Phadke, JM Navenot, DR Hurst, MA Accavitti-Loper, E Sztul, ...
Journal of the National Cancer Institute 99 (4), 309-321, 2007
1892007
Inhibition of CXCR4 by CTCE-9908 inhibits breast cancer metastasis to lung and bone
MM Richert, KS Vaidya, CN Mills, D Wong, W Korz, DR Hurst, DR Welch
Oncology reports 21 (3), 761-767, 2009
1742009
Metastasis suppressor genes: at the interface between the environment and tumor cell growth
DR Hurst, DR Welch
International review of cell and molecular biology 286, 107-180, 2011
1572011
Matrix metalloproteinase inhibitors as prospective agents for the prevention and treatment of cardiovascular and neoplastic diseases
QXA Sang, Y Jin, RG Newcomer, SC Monroe, X Fang, DR Hurst, S Lee, ...
Current topics in medicinal chemistry 6 (4), 289-316, 2006
1452006
BRMS1 suppresses breast cancer experimental metastasis to multiple organs by inhibiting several steps of the metastatic process
PA Phadke, KS Vaidya, KT Nash, DR Hurst, DR Welch
The American journal of pathology 172 (3), 809-817, 2008
1402008
Heparanase-mediated loss of nuclear syndecan-1 enhances histone acetyltransferase (HAT) activity to promote expression of genes that drive an aggressive tumor phenotype
A Purushothaman, DR Hurst, C Pisano, S Mizumoto, K Sugahara, ...
Journal of Biological Chemistry 286 (35), 30377-30383, 2011
1242011
Breast cancer metastasis suppressor 1 coordinately regulates metastasis‐associated microRNA expression
MD Edmonds, DR Hurst, KS Vaidya, LJ Stafford, D Chen, DR Welch
International Journal of Cancer 125 (8), 1778-1785, 2009
1092009
Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells
DR Hurst, Y Xie, KS Vaidya, A Mehta, BP Moore, MA Accavitti-Loper, ...
Journal of Biological Chemistry 283 (12), 7438-7444, 2008
902008
Gli1 enhances migration and invasion via up-regulation of MMP-11 and promotes metastasis in ERα negative breast cancer cell lines
YJ Kwon, DR Hurst, AD Steg, K Yuan, KS Vaidya, DR Welch, AR Frost
Clinical & experimental metastasis 28, 437-449, 2011
862011
Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone
DR Hurst, A Mehta, BP Moore, PA Phadke, WJ Meehan, MA Accavitti, ...
Biochemical and biophysical research communications 348 (4), 1429-1435, 2006
842006
Metastasis suppressors and the tumor microenvironment
LM Cook, DR Hurst, DR Welch
Seminars in cancer biology 21 (2), 113-122, 2011
782011
Breast cancer metastasis suppressor-1 differentially modulates growth factor signaling
KS Vaidya, S Harihar, PA Phadke, LJ Stafford, DR Hurst, DG Hicks, ...
Journal of biological chemistry 283 (42), 28354-28360, 2008
732008
SOCS3 deficiency in myeloid cells promotes tumor development: involvement of STAT3 activation and myeloid-derived suppressor cells
H Yu, Y Liu, BC McFarland, JS Deshane, DR Hurst, S Ponnazhagan, ...
Cancer immunology research 3 (7), 727-740, 2015
692015
The intermediate S1′ pocket of the endometase/matrilysin-2 active site revealed by enzyme inhibition kinetic studies, protein sequence analyses, and homology modeling
HI Park, Y Jin, DR Hurst, CA Monroe, S Lee, MA Schwartz, QXA Sang
Journal of Biological Chemistry 278 (51), 51646-51653, 2003
692003
Histone deacetylase inhibitors improve the replication of oncolytic herpes simplex virus in breast cancer cells
JJ Cody, JM Markert, DR Hurst
PloS one 9 (3), e92919, 2014
652014
Catalytic-and ecto-domains of membrane type 1-matrix metalloproteinase have similar inhibition profiles but distinct endopeptidase activities
DR Hurst, MA Schwartz, MA Ghaffari, Y Jin, H Tschesche, GB Fields, ...
Biochemical Journal 377 (3), 775-779, 2004
602004
Unraveling the enigmatic complexities of BRMS1-mediated metastasis suppression
DR Hurst, DR Welch
FEBS letters 585 (20), 3185-3190, 2011
522011
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Articles 1–20