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Benjamin G. Hale
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The multifunctional NS1 protein of influenza A viruses
BG Hale, RE Randall, J Ortín, D Jackson
Journal of General Virology 89 (10), 2359-2376, 2008
13802008
Influenza A virus NS1 protein binds p85β and activates phosphatidylinositol-3-kinase signaling
BG Hale, D Jackson, YH Chen, RA Lamb, RE Randall
Proceedings of the National Academy of Sciences 103 (38), 14194-14199, 2006
3422006
Innate immune evasion strategies of influenza viruses
BG Hale, RA Albrecht, A García-Sastre
Future Microbiology 5 (1), 23-41, 2010
2142010
Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein
BG Hale, J Steel, RA Medina, B Manicassamy, J Ye, D Hickman, R Hai, ...
Journal of Virology 84 (14), 6909-6922, 2010
2032010
Interplay between viruses and host SUMOylation pathways
RD Everett, C Boutell, BG Hale
Nature Reviews Microbiology 11 (6), 400-411, 2013
1872013
Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species
M Schmolke, B Manicassamy, L Pena, T Sutton, R Hai, ZT Varga, BG Hale, ...
PLOS Pathogens 7 (8), e1002186, 2011
1542011
Antiviral Activity of Type I, II, and III Interferons Counterbalances ACE2 Inducibility and Restricts SARS-CoV-2
I Busnadiego, S Fernbach, MO Pohl, U Karakus, M Huber, A Trkola, ...
mBio 11 (5), 2020
1452020
Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein
BG Hale, PS Kerry, D Jackson, BL Precious, A Gray, MJ Killip, RE Randall, ...
Proceedings of the National Academy of Sciences 107 (5), 1954-1959, 2010
1282010
MHC class II proteins mediate cross-species entry of bat influenza viruses
U Karakus, T Thamamongood, K Ciminski, W Ran, SC Günther, MO Pohl, ...
Nature 567 (7746), 109-112, 2019
1202019
Structure of an avian influenza A virus NS1 protein effector domain
BG Hale, WS Barclay, RE Randall, RJ Russell
Virology 378 (1), 1-5, 2008
1182008
Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein
GA Versteeg, BG Hale, S van Boheemen, T Wolff, DJ Lenschow, ...
Journal of Virology 84 (10), 5423-5430, 2010
972010
Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85β suggests a novel mechanism for phosphoinositide 3-kinase activation
BG Hale, IH Batty, CP Downes, RE Randall
Journal of Biological Chemistry 283 (3), 1372-1380, 2008
932008
Global reprogramming of host SUMOylation during influenza virus infection
P Domingues, F Golebiowski, MH Tatham, AM Lopes, A Taggart, RT Hay, ...
Cell Reports 13 (7), 1467-1480, 2015
922015
CDK/ERK-mediated phosphorylation of the human influenza A virus NS1 protein at threonine-215
BG Hale, A Knebel, CH Botting, CS Galloway, BL Precious, D Jackson, ...
Virology 383 (1), 6-11, 2009
922009
An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity
N Schmidt, P Domingues, F Golebiowski, C Patzina, MH Tatham, RT Hay, ...
Proceedings of the National Academy of Sciences 116 (35), 17399-17408, 2019
842019
Conformational plasticity of the influenza A virus NS1 protein
BG Hale
Journal of General Virology 95 (10), 2099-2105, 2014
802014
Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo
RA Benson, MKL MacLeod, BG Hale, A Patakas, P Garside, JM Brewer
eLife 4, e06994, 2015
782015
A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence
J Ayllon, P Domingues, R Rajsbaum, L Miorin, M Schmolke, BG Hale, ...
Journal of Virology 88 (20), 12146-12151, 2014
782014
Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus
BG Hale, J Steel, B Manicassamy, RA Medina, J Ye, D Hickman, ...
Journal of General Virology 91 (7), 1737-1742, 2010
762010
Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection
L Echavarría-Consuegra, GM Cook, I Busnadiego, C Lefèvre, S Keep, ...
PLOS Pathogens 17 (6), e1009644, 2021
732021
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