Systematic integration of biomedical knowledge prioritizes drugs for repurposing DS Himmelstein, A Lizee, C Hessler, L Brueggeman, SL Chen, D Hadley, ... Elife 6, e26726, 2017 | 422 | 2017 |
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease J Bryois, NG Skene, TF Hansen, LJA Kogelman, HJ Watson, Z Liu, ... Nature genetics 52 (5), 482-493, 2020 | 222 | 2020 |
Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes P Feliciano, X Zhou, I Astrovskaya, TN Turner, T Wang, L Brueggeman, ... NPJ genomic medicine 4 (1), 19, 2019 | 186 | 2019 |
Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes X Zhou, P Feliciano, C Shu, T Wang, I Astrovskaya, JB Hall, JU Obiajulu, ... Nature genetics 54 (9), 1305-1319, 2022 | 119 | 2022 |
Forecasting risk gene discovery in autism with machine learning and genome-scale data L Brueggeman, T Koomar, JJ Michaelson Scientific reports 10 (1), 4569, 2020 | 42 | 2020 |
Drug repositioning in epilepsy reveals novel antiseizure candidates L Brueggeman, ML Sturgeon, RM Martin, AJ Grossbach, Y Nagahama, ... Annals of clinical and translational neurology 6 (2), 295-309, 2019 | 41 | 2019 |
Neuronal PAS domain proteins 1 and 3 are master regulators of neuropsychiatric risk genes JJ Michaelson, MK Shin, JY Koh, L Brueggeman, A Zhang, A Katzman, ... Biological psychiatry 82 (3), 213-223, 2017 | 33 | 2017 |
Beliefs in vaccine as causes of autism among SPARK cohort caregivers E Fombonne, RP Goin-Kochel, BJ O'Roak, L Abbeduto, G Aberbach, ... Vaccine 38 (7), 1794-1803, 2020 | 27 | 2020 |
Association of copy number variation signature and survival in patients with serous ovarian cancer RP Graf, R Eskander, L Brueggeman, DG Stupack JAMA Network Open 4 (6), e2114162-e2114162, 2021 | 21 | 2021 |
Genetic Identification of Cell Types Underlying Brain Complex Traits Yields Novel Insights Into the Etiology of Parkinson’s Disease J Bryois, NG Skene, TF Hansen, L Kogelman, HJ Watson, Z Liu, ... bioRxiv, 528463, 2019 | 20 | 2019 |
Heterochromatin formation via recruitment of DNA repair proteins JG Kirkland, MR Peterson, CD Still, L Brueggeman, N Dhillon, ... Molecular biology of the cell 26 (7), 1395-1410, 2015 | 11 | 2015 |
Train marshalling is fixed parameter tractable L Brueggeman, M Fellows, R Fleischer, M Lackner, C Komusiewicz, ... Fun with Algorithms: 6th International Conference, FUN 2012, Venice, Italy …, 2012 | 9 | 2012 |
Rephetio: Repurposing drugs on a hetnet D Himmelstein, A Lizee, P Khankhanian, L Brueggeman, S Chen, ... Thinklab, 2015 | 8 | 2015 |
Integrating de novo and inherited variants in over 42,607 autism cases identifies mutations in new moderate risk genes X Zhou, P Feliciano, T Wang, I Astrovskaya, C Shu, JB Hall, JU Obiajulu, ... medRxiv, 2021.10. 08.21264256, 2021 | 7 | 2021 |
Genetic and morphological estimates of androgen exposure predict social deficits in multiple neurodevelopmental disorder cohorts BG McKenna, Y Huang, K Vervier, D Hofammann, M Cafferata, ... Molecular autism 12 (1), 43, 2021 | 7 | 2021 |
Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes. NPJ Genomic Medicine. 2019; 4: 19 P Feliciano, X Zhou, I Astrovskaya, TN Turner, T Wang, L Brueggeman, ... | 5 | |
Ensemble modeling of neurocognitive performance using MRI-derived brain structure volumes L Brueggeman, T Koomar, Y Huang, B Hoskins, T Tong, J Kent, E Bahl, ... Adolescent Brain Cognitive Development Neurocognitive Prediction: First …, 2019 | 2 | 2019 |
eP121: Integrating de novo and inherited variants in over 42,607 autism cases identifies variants in new moderate risk genes P Feliciano, X Zhou, T Wang, I Astrovskaya, C Shu, J Hall, J Obiajulu, ... Genetics in Medicine 24 (3), S76, 2022 | 1 | 2022 |
Sex Differences in the Brain: Divergent Results from Traditional Machine Learning and Convolutional Networks L Brueggeman, TR Thomas, T Koomar, B Hoskins, JJ Michaelson 2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI), 1-4, 2020 | 1 | 2020 |
Identifying genomic risk factors for neurodevelopmental disorders using machine learning L Brueggeman The University of Iowa, 2022 | | 2022 |