| Base editing with a Cpf1–cytidine deaminase fusion X Li, Y Wang, Y Liu, B Yang, X Wang, J Wei, Z Lu, Y Zhang, J Wu, ... Nature biotechnology 36 (4), 324-327, 2018 | 437 | 2018 |
| Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion X Wang, J Li, Y Wang, B Yang, J Wei, J Wu, R Wang, X Huang, J Chen, ... Nature biotechnology 36 (10), 946-949, 2018 | 236 | 2018 |
| Correction of the Marfan syndrome pathogenic FBN1 mutation by base editing in human cells and heterozygous embryos Y Zeng, J Li, G Li, S Huang, W Yu, Y Zhang, D Chen, J Chen, J Liu, ... Molecular Therapy 26 (11), 2631-2637, 2018 | 158 | 2018 |
| Efficient generation of mouse models of human diseases via ABE-and BE-mediated base editing Z Liu, Z Lu, G Yang, S Huang, G Li, S Feng, Y Liu, J Li, W Yu, Y Zhang, ... Nature Communications 9 (1), 2338, 2018 | 150 | 2018 |
| BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity W Jiang, S Feng, S Huang, W Yu, G Li, G Yang, Y Liu, Y Zhang, L Zhang, ... Cell research 28 (8), 855-861, 2018 | 141 | 2018 |
| Enhanced base editing by co-expression of free uracil DNA glycosylase inhibitor L Wang, W Xue, L Yan, X Li, J Wei, M Chen, J Wu, B Yang, L Yang, ... Cell Research, 2017 | 133 | 2017 |
| Repair of naturally occurring mismatches can induce mutations in flanking DNA J Chen, BF Miller, AV Furano Elife 3, e02001, 2014 | 105 | 2014 |
| Highly efficient and precise base editing in discarded human tripronuclear embryos G Li, Y Liu, Y Zeng, J Li, L Wang, G Yang, D Chen, X Shang, J Chen, ... Protein & Cell 8 (10), 776-779, 2017 | 93 | 2017 |
| TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation L Lei, Y Xiong, J Chen, JB Yang, Y Wang, XY Yang, CCY Chang, ... Journal of lipid research 50 (6), 1057-1067, 2009 | 85 | 2009 |
| Enhancement of human ACAT1 gene expression to promote the macrophage-derived foam cell formation by dexamethasone L Yang, JB Yang, J Chen, GY Yu, P Zhou, LEI Lei, ZZ Wang, CC Chang, ... Cell research 14 (4), 315, 2004 | 83 | 2004 |
| Cas12a base editors induce efficient and specific editing with low DNA damage response X Wang, C Ding, W Yu, Y Wang, S He, B Yang, YC Xiong, J Wei, J Li, ... Cell reports 31 (9), 2020 | 71 | 2020 |
| Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure X Li, L Zhou, BQ Gao, G Li, X Wang, Y Wang, J Wei, W Han, Z Wang, J Li, ... Nature Communications 13 (1), 1669, 2022 | 66 | 2022 |
| Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations L Wang, W Xue, H Zhang, R Gao, H Qiu, J Wei, L Zhou, YN Lei, X Wu, X Li, ... Nature Cell Biology 23 (5), 552-563, 2021 | 64 | 2021 |
| Development and Application of Base Editors B Yang, L Yang, J Chen The CRISPR Journal 2 (2), 91-104, 2019 | 63 | 2019 |
| APOBEC: From mutator to editor B Yang, X Li, L Lei, J Chen Journal of Genetics and Genomics, 2017 | 63 | 2017 |
| APOBEC3 induces mutations during repair of CRISPR–Cas9-generated DNA breaks L Lei, H Chen, W Xue, B Yang, B Hu, J Wei, L Wang, Y Cui, W Li, J Wang, ... Nature structural & molecular biology 25 (1), 45-52, 2018 | 48 | 2018 |
| Human acyl-coenzyme A: cholesterol acyltransferase 1 (acat1) sequences located in two different chromosomes (7 and 1) are required to produce a novel ACAT1 isoenzyme with … L Yang, O Lee, J Chen, J Chen, CCY Chang, P Zhou, ZZ Wang, HH Ma, ... Journal of Biological Chemistry 279 (44), 46253-46262, 2004 | 43 | 2004 |
| Genomic and Transcriptomic Analyses of Prime Editing Guide RNA–independent Off-target Effects by Prime Editors R Gao, ZC Fu, X Li, Y Wang, J Wei, G Li, L Wang, J Wu, X Huang, L Yang, ... The CRISPR Journal 5 (2), 276-293, 2022 | 37 | 2022 |
| One Prime for All Editing L Yang, B Yang, J Chen Cell 179 (7), 1448-1450, 2019 | 34 | 2019 |
| Breaking bad: The mutagenic effect of DNA repair J Chen, AV Furano DNA repair 32, 43-51, 2015 | 32 | 2015 |
Li YangFudan UniversityVerified email at fudan.edu.cn
