| Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology W Van Rheenen, RAA Van Der Spek, MK Bakker, JJFA Van Vugt, PJ Hop, ... Nature genetics 53 (12), 1636-1648, 2021 | 275 | 2021 |
| Genetic insights into biological mechanisms governing human ovarian ageing KS Ruth, FR Day, J Hussain, A Martínez-Marchal, CE Aiken, A Azad, ... Nature 596 (7872), 393-397, 2021 | 212 | 2021 |
| A practical view of fine-mapping and gene prioritization in the post-genome-wide association era RV Broekema, OB Bakker, IH Jonkers Open biology 10 (1), 190221, 2020 | 120 | 2020 |
| Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses OB Bakker, R Aguirre-Gamboa, S Sanna, M Oosting, SP Smeekens, ... Nature immunology 19 (7), 776-786, 2018 | 114 | 2018 |
| Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases N de Klein, EA Tsai, M Vochteloo, D Baird, Y Huang, CY Chen, ... Nature genetics 55 (3), 377-388, 2023 | 97 | 2023 |
| Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort K Mc Intyre, P Lanting, P Deelen, HH Wiersma, JM Vonk, APS Ori, ... BMJ open 11 (3), e044474, 2021 | 49 | 2021 |
| Deconvolution of bulk blood eQTL effects into immune cell subpopulations R Aguirre-Gamboa, N de Klein, J di Tommaso, A Claringbould, ... BMC bioinformatics 21, 1-23, 2020 | 47 | 2020 |
| Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease X Chu, M Jaeger, J Beumer, OB Bakker, R Aguirre-Gamboa, M Oosting, ... Genome biology 22, 1-22, 2021 | 31 | 2021 |
| An integrative genomics approach identifies KDM4 as a modulator of trained immunity SJ Moorlag, V Matzaraki, JH van Puffelen, C van der Heijden, S Keating, ... European journal of immunology 52 (3), 431-446, 2022 | 29 | 2022 |
| Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response DH de Vries, V Matzaraki, OB Bakker, H Brugge, HJ Westra, MG Netea, ... PLoS pathogens 16 (4), e1008408, 2020 | 23 | 2020 |
| Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases N Klein, EA Tsai, M Vochteloo, D Baird, Y Huang, CY Chen, S Dam, ... Nat Genet 55, 377-88, 2023 | 18 | 2023 |
| Evolution of cytokine production capacity in ancient and modern European populations J Domínguez-Andrés, Y Kuijpers, OB Bakker, M Jaeger, CJ Xu, ... Elife 10, e64971, 2021 | 17 | 2021 |
| Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: results from the REPAIR … JM Sánchez-Maldonado, R Cáliz, L Canet, R Horst, O Bakker, ... Scientific Reports 9 (1), 14812, 2019 | 10 | 2019 |
| Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells OB Bakker, AD Ramírez-Sánchez, ZA Borek, N de Klein, Y Li, ... Scientific reports 11 (1), 9252, 2021 | 9 | 2021 |
| Type 2 diabetes-related variants influence the risk of developing prostate cancer: A population-based case-control study and meta-analysis JM Sánchez-Maldonado, R Collado, AJ Cabrera-Serrano, R Ter Horst, ... Cancers 14 (10), 2376, 2022 | 8 | 2022 |
| Linking common and rare disease genetics through gene regulatory networks OB Bakker, A Claringbould, HJ Westra, H Wiersma, F Boulogne, U Võsa, ... medRxiv, 2021.10. 21.21265342, 2021 | 8 | 2021 |
| The Lifelines COVID-19 Cohort: a questionnaire-based study to investigate COVID-19 infection and its health and societal impacts in a Dutch population-based cohort KM Intyre, P Lanting, P Deelen, H Wiersma, JM Vonk, APS Ori, ... medRxiv, 2020.06. 19.20135426, 2020 | 8 | 2020 |
| Evolutionary trajectories of complex traits in European populations of modern humans Y Kuijpers, J Domínguez-Andrés, OB Bakker, MK Gupta, M Grasshoff, ... Frontiers in Genetics 13, 833190, 2022 | 6 | 2022 |
| Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific … W van Rheenen, RAA van der Spek, MK Bakker, JJFA van Vugt, PJ Hop, ... Nature genetics 54 (3), 361-361, 2022 | 1 | 2022 |
| Integration of similar to 10,000 metabolite features with genotype data and immune phenotypes reveals genetic determinants and common regulatory modules X Chu, M Jaeger, OB Bakker, R Aguirre-Gamboa, M Oosting, ... European Journal of Human Genetics 27, 787-787, 2019 | 1 | 2019 |
