| Induction of human cardiomyocyte-like cells from fibroblasts by defined factors R Wada, N Muraoka, K Inagawa, H Yamakawa, K Miyamoto, T Sadahiro, ... Proceedings of the National Academy of Sciences 110 (31), 12667-12672, 2013 | 353 | 2013 |
| MiR‐133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures N Muraoka, H Yamakawa, K Miyamoto, T Sadahiro, T Umei, M Isomi, ... The EMBO journal 33 (14), 1565-1581, 2014 | 322 | 2014 |
| Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5 K Inagawa, K Miyamoto, H Yamakawa, N Muraoka, T Sadahiro, T Umei, ... Circulation research 111 (9), 1147-1156, 2012 | 316 | 2012 |
| Fibroblast growth factors and vascular endothelial growth factor promote cardiac reprogramming under defined conditions H Yamakawa, N Muraoka, K Miyamoto, T Sadahiro, M Isomi, S Haginiwa, ... Stem cell reports 5 (6), 1128-1142, 2015 | 169 | 2015 |
| Direct in vivo reprogramming with Sendai virus vectors improves cardiac function after myocardial infarction K Miyamoto, M Akiyama, F Tamura, M Isomi, H Yamakawa, T Sadahiro, ... Cell stem cell 22 (1), 91-103. e5, 2018 | 167 | 2018 |
| Direct cardiac reprogramming: progress and challenges in basic biology and clinical applications T Sadahiro, S Yamanaka, M Ieda Circulation research 116 (8), 1378-1391, 2015 | 140 | 2015 |
| Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming N Muraoka, K Nara, F Tamura, H Kojima, H Yamakawa, T Sadahiro, ... Nature communications 10 (1), 674, 2019 | 82 | 2019 |
| Progress and challenge of cardiac regeneration to treat heart failure M Isomi, T Sadahiro, M Ieda Journal of cardiology 73 (2), 97-101, 2019 | 70 | 2019 |
| Soft matrix promotes cardiac reprogramming via inhibition of YAP/TAZ and suppression of fibroblast signatures S Kurotsu, T Sadahiro, R Fujita, H Tani, H Yamakawa, F Tamura, M Isomi, ... Stem cell reports 15 (3), 612-628, 2020 | 59 | 2020 |
| Tbx6 induces nascent mesoderm from pluripotent stem cells and temporally controls cardiac versus somite lineage diversification T Sadahiro, M Isomi, N Muraoka, H Kojima, S Haginiwa, S Kurotsu, ... Cell Stem Cell 23 (3), 382-395. e5, 2018 | 59 | 2018 |
| Real‐time analysis of the heart rate variability during incremental exercise for the detection of the ventilatory threshold Y Shiraishi, Y Katsumata, T Sadahiro, K Azuma, K Akita, S Isobe, ... Journal of the American Heart Association 7 (1), e006612, 2018 | 57 | 2018 |
| Direct cardiac reprogramming: a novel approach for heart regeneration H Tani, T Sadahiro, M Ieda International journal of molecular sciences 19 (9), 2629, 2018 | 42 | 2018 |
| Direct reprogramming improves cardiac function and reverses fibrosis in chronic myocardial infarction H Tani, T Sadahiro, Y Yamada, M Isomi, H Yamakawa, R Fujita, Y Abe, ... Circulation 147 (3), 223-238, 2023 | 31 | 2023 |
| Single-construct polycistronic doxycycline-inducible vectors improve direct cardiac reprogramming and can be used to identify the critical timing of transgene expression TC Umei, H Yamakawa, N Muraoka, T Sadahiro, M Isomi, S Haginiwa, ... International journal of molecular sciences 18 (8), 1805, 2017 | 26 | 2017 |
| Direct reprogramming with Sendai virus vectors repaired infarct hearts at the chronic stage M Isomi, T Sadahiro, R Fujita, Y Abe, Y Yamada, T Akiyama, H Mizukami, ... Biochemical and biophysical research communications 560, 87-92, 2021 | 23 | 2021 |
| Cardiac regeneration with pluripotent stem cell-derived cardiomyocytes and direct cardiac reprogramming T Sadahiro Regenerative therapy 11, 95-100, 2019 | 23 | 2019 |
| Distinct expression patterns of Flk1 and Flt1 in the coronary vascular system during development and after myocardial infarction S Kurotsu, R Osakabe, M Isomi, F Tamura, T Sadahiro, N Muraoka, ... Biochemical and biophysical research communications 495 (1), 884-891, 2018 | 18 | 2018 |
| MRI and serum high-sensitivity C reactive protein predict long-term mortality in non-ischaemic cardiomyopathy T Sadahiro, S Kohsaka, S Okuda, T Inohara, Y Shiraishi, T Kohno, ... Open Heart 2 (1), e000298, 2015 | 18 | 2015 |
| In vivo reprogramming as a new approach to cardiac regenerative therapy T Sadahiro, M Ieda Seminars in Cell & Developmental Biology 122, 21-27, 2022 | 16 | 2022 |
| Overexpression of Gata4, Mef2c, and Tbx5 generates induced cardiomyocytes via direct reprogramming and rare fusion in the heart M Isomi, T Sadahiro, H Yamakawa, R Fujita, Y Yamada, Y Abe, ... Circulation 143 (21), 2123-2125, 2021 | 11 | 2021 |
