| 14-3-3ζ Turns TGF-β’s Function from Tumor Suppressor to Metastasis Promoter in Breast Cancer by Contextual Changes of Smad Partners from p53 to Gli2 J Xu, S Acharya, O Sahin, Q Zhang, Y Saito, J Yao, H Wang, P Li, L Zhang, ... Cancer Cell 27 (2), 177-192, 2015 | 185 | 2015 |
| Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells A Kumar, J Xu, S Brady, H Gao, D Yu, J Reuben, K Mehta PloS one 5 (10), e13390, 2010 | 152 | 2010 |
| Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit CL Neal, J Xu, P Li, S Mori, J Yang, NN Neal, X Zhou, SL Wyszomierski, ... Oncogene 31 (7), 897-906, 2012 | 118 | 2012 |
| Tumor suppressor genes are frequently methylated in lymph node metastases of breast cancers W Feng, R Orlandi, N Zhao, ML Carcangiu, E Tagliabue, J Xu, RC Bast, ... BMC cancer 10, 1-10, 2010 | 80 | 2010 |
| Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome J Xu, PB Shetty, W Feng, C Chenault, RC Bast, JPJ Issa, SG Hilsenbeck, ... BMC cancer 12 (1), 243, 2012 | 79 | 2012 |
| p53 maintains baseline expression of multiple tumor suppressor genes K Pappas, J Xu, S Zairis, L Resnick-Silverman, F Abate, N Steinbach, ... Molecular Cancer Research 15 (8), 1051-1062, 2017 | 74 | 2017 |
| Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells A Kumar, J Xu, B Sung, S Kumar, D Yu, BB Aggarwal, K Mehta Breast Cancer Research 14, 1-15, 2012 | 74 | 2012 |
| Evidence that aberrant expression of tissue transglutaminase promotes stem cell characteristics in mammary epithelial cells A Kumar, H Gao, J Xu, J Reuben, D Yu, K Mehta PLoS One 6 (6), e20701, 2011 | 72 | 2011 |
| Upregulation of Neutrophil Gelatinase–Associated Lipocalin by ErbB2 through Nuclear Factor-κB Activation SH Li, VS Hawthorne, CL Neal, S Sanghera, J Xu, J Yang, H Guo, ... Cancer research 69 (24), 9163-9168, 2009 | 43 | 2009 |
| AKT Degradation Selectively Inhibits the Growth of PI3K/PTEN Pathway–Mutant Cancers with Wild-Type KRAS and BRAF by Destabilizing Aurora Kinase B J Xu, X Yu, TC Martin, A Bansal, K Cheung, A Lubin, E Stratikopoulos, ... Cancer discovery 11 (12), 3064-3089, 2021 | 38 | 2021 |
| Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression CC Chang, C Zhang, Q Zhang, O Sahin, H Wang, J Xu, Y Xiao, J Zhang, ... Oncotarget 7 (23), 35270, 2016 | 37 | 2016 |
| Mir-20a-5p induced WTX deficiency promotes gastric cancer progressions through regulating PI3K/AKT signaling pathway J Li, D Ye, P Shen, X Liu, P Zhou, G Zhu, Y Xu, Y Fu, X Li, J Sun, J Xu, ... Journal of Experimental & Clinical Cancer Research 39, 1-17, 2020 | 36 | 2020 |
| Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders X Yu, J Xu, L Xie, L Wang, Y Shen, KM Cahuzac, X Chen, J Liu, ... Journal of medicinal chemistry 64 (24), 18054-18081, 2021 | 29 | 2021 |
| Isolation and RNA1 nucleotide sequence determination of a new insect nodavirus from Pieris rapae larvae in Wuhan city, China C Liu, J Zhang, F Yi, J Wang, X Wang, H Jiang, J Xu, Y Hu Virus research 120 (1-2), 28-35, 2006 | 25 | 2006 |
| Discovery of Potent, Selective, and In Vivo Efficacious AKT Kinase Protein Degraders via Structure–Activity Relationship Studies X Yu, J Xu, Y Shen, KM Cahuzac, K Park, B Dale, J Liu, RE Parsons, J Jin Journal of Medicinal Chemistry 65 (4), 3644-3666, 2022 | 24 | 2022 |
| Downregulation of GLUT4 contributes to effective intervention of estrogen receptor-negative/HER2-overexpressing early stage breast disease progression by lapatinib S Acharya, J Xu, X Wang, S Jain, H Wang, Q Zhang, CC Chang, J Bower, ... American Journal of Cancer Research 6 (5), 981, 2016 | 18 | 2016 |
| A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma RW Zhou, J Xu, TC Martin, AL Zachem, J He, S Ozturk, D Demircioglu, ... Nature Communications 13 (1), 1-17, 2022 | 13 | 2022 |
| Novel Allosteric Inhibitor-Derived AKT Proteolysis Targeting Chimeras (PROTACs) Enable Potent and Selective AKT Degradation in KRAS/BRAF Mutant Cells X Yu, J Xu, KM Cahuzac, L Xie, Y Shen, X Chen, J Liu, RE Parsons, J Jin Journal of Medicinal Chemistry 65 (20), 14237-14260, 2022 | 10 | 2022 |
| Comparison of Heliothis armigera NPV VHA~ 2~ 7~ 3 Wild Isolate with Its Clone F Jia, J Xu, Y Nie, Y XIAO, R ZHOU, X LI, Z YU Virologica Sinica 18 (3), 241-245, 2003 | 2 | 2003 |
| Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation K Mendelson, TC Martin, CB Nguyen, M Hsu, J Xu, C Lang, R Dummer, ... JCI insight 9 (6), 2024 | | 2024 |
